Two types of phosphatidylinositol 3-kinase from bovine thymus. Monomer and heterodimer form

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

1988 • 1,027 citations

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

1989 • 933 citations

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

1987 • 670 citations

Activation of phosphatidylinositol 3-kinase by insulin.

1990 • 531 citations

Role of Phosphatidylinositol Kinase in PDGF Receptor Signal Transduction

1989 • 516 citations

An 81 kd protein complexed with middle T antigen and pp60c-src: A possible phosphatidylinositol kinase

1987 • 346 citations

The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase

1989 • 342 citations

Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Implications for cellular regulation

1987 • 307 citations

Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor tyrosine kinase.

1990 • 266 citations

Polyphosphoinositides Produced by Phosphatidylinositol 3-Kinase Are Poor Substrates for Phospholipases C from Rat Liver and Bovine Brain

1989 • 238 citations

Phosphatidylinositol kinase activity associates with viral p60src protein.

1989 • 194 citations

Phosphorylation of middle T by pp60c-src: A switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesis

1989 • 178 citations

Phosphoinositide metabolism and the control of cell proliferation

1989 • 165 citations

Phosphatidylinositol 3-Phosphate Is Present in Normal and Transformed Fibroblasts and Is Resistant to Hydrolysis by Bovine Brain Phospholipase C II

1989 • 137 citations

Altered signal transduction in erbB-transformed cells. Implication of enhanced inositol phospholipid metabolism in erbB-induced transformation.

1987 • 62 citations

Mechanisms of transformation by polyoma virus middle T antigen

1989 • 58 citations

Purification and characterization of membrane-bound phosphatidylinositol kinase from rat brain.

1988 • 49 citations

The identification of a novel inositol lipid, phosphatidylinostiol trisphosphate (PIP3), in rat cerebrum using in vivo techniques

1989 • 42 citations