The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

1988 • 1,027 citations

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

1989 • 933 citations

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

1985 • 813 citations

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

1987 • 670 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1987 • 567 citations

Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor

1984 • 520 citations

Role of Phosphatidylinositol Kinase in PDGF Receptor Signal Transduction

1989 • 516 citations

Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1981 • 492 citations

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor)

1987 • 357 citations

Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Implications for cellular regulation

1987 • 307 citations

Methods for the purification, assay, characterization and target cell binding of a colony stimulating factor (CSF-1)

1981 • 274 citations

A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential

1988 • 242 citations

Isolation and characterization of a cloned growth factor dependent macrophage cell line, BAC1.2F5

1987 • 209 citations

The interaction of 125I-colony-stimulating factor-1 with bone marrow-derived macrophages.

1986 • 205 citations

Characterization and use of monoclonal antibodies for isolation of phosphotyrosyl proteins from retrovirus-transformed cells and growth factor-stimulated cells.

1983 • 200 citations

Phosphatidylinositol kinase activity associates with viral p60src protein.

1989 • 194 citations

The haemopoietic growth factors interleukin 3 and colony stimulating factor-1 stimulate proliferation but do not induce inositol lipid breakdown in murine bone-marrow-derived macrophages.

1986 • 90 citations

Discrimination of a colony stimulating factor subclass by a specific receptor on a macrophage cell line

1980 • 76 citations

Tyrosine phosphorylations in vivo associated with v-fms transformation.

1988 • 59 citations

Factors Affecting the Growth and Differentiation of Haemopoietic Cells in Culture

1984 • 49 citations

Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: separation of focus formation and soft-agar growth in transformation assays and correlations with kinase activities in vitro

1988 • 31 citations

Uptake and destruction of ¹²⁵I‐CSF‐1 by peritoneal exudate macrophages

1986 • 26 citations