Promoter activity and distance constraints of one versus two Sp1 binding sites.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1

1986 • 1,473 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

Promoter-specific activation of RNA polymerase II transcription by Sp1

1986 • 1,054 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

[36] Eukaryotic gene transcription with purified components

1983 • 992 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Activators and targets

1990 • 582 citations

Multiple specific contacts between a mammalian transcription factor and its cognate promoters

1984 • 565 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

Functional Domains and Upstream Activation Properties of Cloned Human TATA Binding Protein

1990 • 471 citations

ADENOVIRUS PROMOTERS AND E1A TRANSACTIVATION

1986 • 460 citations

A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives

1990 • 386 citations

Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter

1986 • 336 citations

Commitment and activation at pol II promoters: A tail of protein-protein interactions

1990 • 332 citations

The SV40 enhancer contains two distinct levels of organization

1988 • 286 citations

How different eukaryotic transcriptional activators can cooperate promiscuously

1990 • 261 citations

Functional relationships between transcriptional control signals of the thymidine kinase gene of herpes simplex virus

1982 • 253 citations

Complete transformation by adenovirus 2 requires both E1A proteins

1984 • 243 citations

Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes

1991 • 242 citations

A TATA box implicated in E1A transcriptional activation of a simple adenovirus 2 promoter

1987 • 227 citations

Promoter specificity and modulation of RNA polymerase II transcription

1989 • 221 citations

Nucleosomes: regulators of transcription

1990 • 186 citations

Cloning of a DNA fragment from the left-hand terminus of the adenovirus type 2 genome and its use in site-directed mutagenesis

1981 • 157 citations

Sp1 activates transcription without enhancing DNA-binding activity of the TATA box factor.

1989 • 123 citations

Periodic interactions of heat shock transcriptional elements

1988 • 81 citations

Constraints on spacing between transcription factor binding sites in a simple adenovirus promoter.

1988 • 62 citations

Organization of the transcriptional control region of the E1b gene of adenovirus type 5

1988 • 49 citations

Transcriptional activation by the pseudorabies virus immediate early protein requires the TATA box element in the adenovirus 2 E1B promoter

1988 • 32 citations