Chapter 35 Serotonin brain circuits involved in major depression and suicide

The human nervous system

2004 • 1,494 citations

The Return of Phineas Gage: Clues About the Brain from the Skull of a Famous Patient

1994 • 1,449 citations

Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter

1994 • 904 citations

Pet imaging of serotonin 1A receptor binding in depression

1999 • 665 citations

A Serotonin Transporter Gene Promoter Polymorphism (5-HTTLPR) and Prefrontal Cortical Binding in Major Depression and Suicide

2000 • 603 citations

Anatomy of the Serotonergic System^a

1990 • 541 citations

Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl)tropane and single photon emission computed tomography

1998 • 507 citations

The domain of supervisory processes and the temporal organization of behaviour

1998 • 492 citations

The neurobiology of suicide

1998 • 475 citations

Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims

1995 • 461 citations

Increase in Serotonin-1A Autoreceptors in the Midbrain of Suicide Victims with Major Depression—Postmortem Evidence for Decreased Serotonin Activity

1998 • 429 citations

Serotonin 1A Receptors, Serotonin Transporter Binding and Serotonin Transporter mRNA Expression in the Brainstem of Depressed Suicide Victims

2001 • 358 citations

Validity of DSM‐III‐R diagnosis by psychological autopsy: a comparison with clinician ante‐mortem diagnosis

1996 • 276 citations

Relationship Between Central and Peripheral Serotonin Indexes in Depressed and Suicidal Psychiatric Inpatients

1992 • 275 citations

Differential projections of the nucleus raphe dorsalis and nucleus raphe centralis as revealed by autoradiography

1975 • 266 citations

Decreased Imipramine Binding in the Brains of Patients with Depressive Illness

1983 • 253 citations

Selective Abnormalities of Prefrontal Serotonergic Receptors in Schizophrenia

1993 • 234 citations

Demonstration in vivo of reduced serotonin responsivity in the brain of untreated depressed patients [published erratum appears in Am J Psychiatry 1996 Apr;153(4):588]

1996 • 184 citations

Evidence for the 5-HT Hypothesis of Suicide A Review of Post-mortem Studies

1989 • 180 citations

[123I]-β-CIT SPECT imaging shows reduced brain serotonin transporter availability in drug-free depressed patients with seasonal affective disorder

2000 • 179 citations

Cytoarchitecture of the human dorsal raphe nucleus

1990 • 166 citations

Morphometry of the dorsal raphe nucleus serotonergic neurons in suicide victims

1999 • 161 citations

The organization of serotonergic projections to cerebral cortex in primates: Regional distribution of axon terminals

1991 • 148 citations

The organization of serotonergic projections to cerebral cortex in primates: Retrograde transport studies

1991 • 127 citations

Raphe Nuclei and the Serotonergic System

1990 • 102 citations

Review of suicidology

1997 • 98 citations

Effects of adrenalectomy and type I or type II glucocorticoid receptor activation on 5-HT1A and 5-HT2 receptor binding and 5-HT transporter mRNA expression in rat brain

1994 • 91 citations

Serotonin transporter binding sites and mRNA levels in depressed persons committing suicide

1997 • 64 citations

The neurobiology of suicide: From the bench to the clinic.

2004 • 60 citations

Recovery from Major Depression Is Not Associated with Normalization of Serotonergic Function

1998 • 59 citations

Lower3H-paroxetine binding in cerebral cortex of suicide victims is partly due to fewer high affinity, non-transporter sites

1996 • 52 citations

Relevance of serotonergic postmortem studies to suicidal behavior

1992 • 35 citations