IL-4, IL-10, IL-13, and TGF-β from an Altered Peptide Ligand-Specific Th2 Cell Clone Down-Regulate Adoptive Transfer of Experimental Autoimmune Encephalomyelitis

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Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1994 • 888 citations

IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages

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1992 • 627 citations

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Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

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1991 • 385 citations

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1998 • 324 citations

IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

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Regulatory CD4+ T Cells Expressing Endogenous T Cell Receptor Chains Protect Myelin Basic Protein–specific Transgenic Mice from Spontaneous Autoimmune Encephalomyelitis

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1995 • 273 citations

Local Delivery of Interleukin 4 by Retrovirus-Transduced T Lymphocytes Ameliorates Experimental Autoimmune Encephalomyelitis

1997 • 264 citations

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1991 • 243 citations

The Primary Binding Subunit of the Human Interleukin-4 Receptor Is Also a Component of the Interleukin-13 Receptor

1995 • 236 citations

A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire.

1994 • 216 citations

Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice. Th2-mediated suppression of autoimmune disease.

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CD4+ suppressor cells inhibit the function of effector cells of experimental autoimmune encephalomyelitis through a mechanism involving transforming growth factor-beta.

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Studies on the mechanisms by which transforming growth factor-beta (TGF-beta) protects against allergic encephalomyelitis. Antagonism between TGF-beta and tumor necrosis factor.

1993 • 170 citations

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1996 • 169 citations

A Critical Role for IL-4 in Regulating Disease Severity in Experimental Allergic Encephalomyelitis as Demonstrated in IL-4-Deficient C57BL/6 Mice and BALB/c Mice

1998 • 161 citations

A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens

1997 • 158 citations

Interleukin‐6 functions in autoimmune encephalomyelitis: a study in gene‐targeted mice

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Acceleration of Experimental Autoimmune Encephalomyelitis in Interleukin-10-Deficient Mice: Roles of Interleukin-10 in Disease Progression and Recovery

1998 • 145 citations

Interleukin-6 functions in autoimmune encephalomyelitis: a study in gene-targeted mice

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A T Helper Cell 2 (Th2) Immune Response against Non-self Antigens Modifies the Cytokine Profile of Autoimmune T Cells and Protects against Experimental Allergic Encephalomyelitis

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Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats.

1994 • 135 citations

Evidence of endogenous regulatory function of transforming growth factor-β1 in experimental allergic encephalomyelitis

1992 • 134 citations

Cytokine-producing cells in experimental autoimmune encephalomyelitis and multiple sclerosis

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Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells.

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A synthetic peptide from myelin proteolipid protein induces experimental allergic encephalomyelitis.

1988 • 126 citations

The immunopathology of experimental allergic encephalomyelitis. I. Quantitative analysis of inflammatory cells in situ.

1984 • 111 citations

Experimental allergic encephalomyelitis: Neutralizing antibody to TGFβ1 enhances the clinical severity of the disease

1993 • 102 citations

Encephalitogenic Th1 cells are inhibited by Th2 cells with related peptide specificity: Relative roles of interleukin (IL)-4 and IL-10

1993 • 101 citations

IL-4 abrogates the inhibitory effect of IL-10 on the development of experimental allergic encephalomyelitis in SJL mice [published erratum appears in Int Immunol 1997 Nov;9(11):1773]

1997 • 76 citations

Dominantly inherited, early‐onset parkinsonism

1993 • 46 citations

Interleukin-13 effects on activated monocytes lead to novel cytokine secretion profiles intermediate between those induced by interleukin-10 and by interferon-gamma.

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Detailed analysis of early immunopathologic events during lesion formation in acute experimental autoimmune encephalomyelitis

1989 • 32 citations

Interleukin-3 and encephalitogenic activity of SJL/J myelin basic protein-specific T cell lines

1993 • 11 citations

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)

1995 • 4 citations