Biosynthesis and function of selenocysteine-containing enzymes.

The selenoenzyme phospholipid hydroperoxide glutathione peroxidase

1985 • 961 citations

Type I iodothyronine deiodinase is a selenocysteine-containing enzyme

1991 • 884 citations

Glutathione : chemical, biochemical, and medical aspects

1989 • 746 citations

The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the ‘termination’ codon, TGA.

1986 • 666 citations

Structure of Ribonuclease H Phased at 2 Å Resolution by MAD Analysis of the Selenomethionyl Protein

1990 • 475 citations

Nucleotide sequence and expression of the selenocysteine-containing polypeptide of formate dehydrogenase (formate-hydrogen-lyase-linked) from Escherichia coli.

1986 • 475 citations

Thyroid hormone metabolism

1986 • 451 citations

Gene for a novel tRNA species that accepts L-serine and cotranslationally inserts selenocysteine

1988 • 434 citations

Purification and characterization of human plasma glutathione peroxidase: A selenoglycoprotein distinct from the known cellular enzyme

1987 • 415 citations

Identification of type I iodothyronine 5′-deiodinase as a selenoenzyme

1990 • 407 citations

SELENIUM BIOCHEMISTRY

1990 • 340 citations

Biosynthesis by Escherichia coli of active altered proteins containing selenium instead of sulfur

1957 • 288 citations

Identification of a selenocysteyl-tRNASer in mammalian cells that recognizes the nonsense codon, UGA

1989 • 281 citations

Identification of a novel translation factor necessary for the incorporation of selenocysteine into protein

1989 • 269 citations

Features of the formate dehydrogenase mRNA necessary for decoding of the UGA codon as selenocysteine.

1990 • 264 citations

Selenosubtilisin as a glutathione peroxidase mimic

1990 • 243 citations

The cDNA for rat selenoprotein P contains 10 TGA codons in the open reading frame

1991 • 238 citations

Cotranslational insertion of selenocysteine into formate dehydrogenase from Escherichia coli directed by a UGA codon.

1987 • 236 citations

Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex.

1982 • 235 citations

Characterization of the major hydroperoxide-reducing activity of human plasma. Purification and properties of a selenium-dependent glutathione peroxidase.

1987 • 233 citations

Selenium and amino acid composition of selenoprotein P, the major selenoprotein in rat serum.

1990 • 217 citations

Purification of protein components of the clostridial glycine reductase system and characterization of protein A as a selenoprotein

1973 • 216 citations

Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase

1991 • 200 citations

Selenocysteine synthase from Escherichia coli. Analysis of the reaction sequence.

1991 • 198 citations

FORMIC DEHYDROGENASE AND THE HYDROGENLYASE ENZYME COMPLEX IN COLI-AEROGENES BACTERIA

1957 • 187 citations

Escherichia coli formate-hydrogen lyase. Purification and properties of the selenium-dependent formate dehydrogenase component.

1990 • 187 citations

Conversion of a protease into an acyl transferase: selenolsubtilisin

1989 • 187 citations

Escherichia coli genes whose products are involved in selenium metabolism

1988 • 182 citations

In vitro synthesis of selenocysteinyl-tRNA(UCA) from seryl-tRNA(UCA): involvement and characterization of the selD gene product.

1990 • 181 citations

UGA is translated as cysteine in pheromone 3 of Euplotes octocarinatus.

1991 • 166 citations

The Amino-Acid Sequence of Bovine Glutathione Peroxidase

1984 • 162 citations

Structure and properties of a bovine liver UGA suppressor serine tRNA with a tryptophan anticodon

1981 • 146 citations

Serine incorporation into the selenocysteine moiety of glutathione peroxidase.

1987 • 146 citations

Selenocysteine synthase from Escherichia coli. Nucleotide sequence of the gene (selA) and purification of the protein.

1991 • 120 citations

Opal suppressor serine tRNAs from bovine liver form phosphoseryl-tRNA.

1982 • 115 citations

Purification and biochemical characterization of SELB, a translation factor involved in selenoprotein synthesis.

1990 • 82 citations

Properties of the selenium-containing moiety of nicotinic acid hydroxylase from Clostridium barkeri

1982 • 75 citations

Selenocysteine, a highly specific component of certain enzymes, is incorporated by a UGA-directed co-translational mechanism.

1988 • 70 citations

Clostridial glycine reductase complex. Purification and characterization of the selenoprotein component.

1977 • 69 citations

Kinetics for formate dehydrogenase of Escherichia coli formate-hydrogenlyase

1991 • 68 citations

Specific Selenium-Containing Macromolecules in the Marine Diatom Thalassiosira pseudonana

1988 • 67 citations

Suppression of termination codons in higher eukaryotes

1985 • 66 citations

Isolation and characterization of a selenium metabolism mutant of Salmonella typhimurium

1988 • 66 citations

STUDIES ON THE ENZYMIC REDUCTION OF AMINO ACIDS

1958 • 62 citations

Expression, purification, and crystallization of natural and selenomethionyl recombinant ribonuclease H from Escherichia coli.

1990 • 61 citations

Selenium-dependent clostridial glycine reductase. Purification and characterization of the two membrane-associated protein components.

1979 • 60 citations

Incorporation and distribution of selenium into thiolase from Clostridium kluyveri.

1985 • 50 citations

Biochemical and genetic analysis of Salmonella typhimurium and Escherichia coli mutants defective in specific incorporation of selenium into formate dehydrogenase and tRNAs.

1989 • 48 citations

A selenomethionine-containing azurin from an auxotroph of Pseudomonas aeruginosa.

1985 • 47 citations

Mechanism of action of clostridial glycine reductase: isolation and characterization of a covalent acetyl enzyme intermediate

1991 • 45 citations

Identification of acetylphosphate as the product of clostridial glycine reductase: evidence for an acyl enzyme intermediate

1989 • 41 citations

Isolation and characterization of a covalent selenocysteine intermediate in the glycine reductase system

1990 • 40 citations

Metalloselenonein, the selenium analogue of metallothionein: synthesis and characterization of its complex with copper ions.

1991 • 40 citations

Escherichia coli formate-to-nitrate respiratory chain: genetic analysis

1982 • 34 citations

A NEW ATP-FORMING REACTION: THE REDUCTIVE DEAMINATION OF GLYCINE

1956 • 30 citations

Selenoprotein A of the clostridial glycine reductase complex: purification and amino acid sequence of the selenocysteine-containing peptide.

1988 • 29 citations

Selenocysteyl‐tRNA occurs in the diatom Thalassiosira and in the ciliate Tetrahymena

1991 • 28 citations

Clostridial glycine reductase: protein C, the acetyl group acceptor, catalyzes the arsenate-dependent decomposition of acetyl phosphate.

1989 • 21 citations