Expression, purification, and crystallization of natural and selenomethionyl recombinant ribonuclease H from Escherichia coli.

Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure.

1990 • 1,013 citations

Crystal structure of core streptavidin determined from multiwavelength anomalous diffraction of synchrotron radiation.

1989 • 579 citations

Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes.

1986 • 483 citations

Preparation and analysis of protein crystals

1982 • 366 citations

Enzyme from Calf Thymus Degrading the RNA Moiety of DNA-RNA Hybrids: Effect on DNA-Dependent RNA Polymerase

1969 • 249 citations

Isolation and Characterization of an Endonuclease from Escherichia coli Specific for Ribonucleic Acid in Ribonucleic Acid·Deoxyribonucleic Acid Hybrid Structures

1973 • 223 citations

Degradation of DNA RNA Hybrids by Ribonuclease H and DNA Polymerases of Cellular and Viral Origin

1972 • 216 citations

Proton-nitrogen-15 heteronuclear NMR studies of Escherichia coli thioredoxin in samples isotopically labeled by residue type

1985 • 212 citations

Transcription antitermination by bacteriophage lambda N gene product

1980 • 205 citations

DNA sequence of the gene coding for Escherichia coli ribonuclease H.

1983 • 167 citations

Structure of interleukin 1 .alpha. at 2.7-.ANG. resolution

1990 • 152 citations

Mechanism of Action of Ribonuclease H Isolated from Avian Myeloblastosis Virus and Escherichia coli

1973 • 136 citations

Multiple origin usage for DNA replication in sdrA(rnh) mutants of Escherichia coli K-12

1984 • 115 citations

Ribonuclease III Does Not Degrade Deoxyribonucleic Acid-Ribonucleic Acid Hybrids

1974 • 113 citations

Direct phase determination based on anomalous scattering

1985 • 112 citations

Mechanism of release of the avian retrovirus tRNATrp primer molecule from viral DNA by ribonuclease H during reverse transcription

1982 • 88 citations

Structure and expression of the dnaQ mutator and the RNase H genes of Escherichia coli: overlap of the promoter regions.

1983 • 79 citations

RNA-primed initiation of Moloney murine leukemia virus plus strands by reverse transcriptase in vitro

1984 • 79 citations

RNase H-defective mutants of Escherichia coli

1986 • 77 citations

Mechanism of RNA primer removal by the RNase H activity of avian myeloblastosis virus reverse transcriptase

1984 • 77 citations

Inhibition of RNase H activity and viral replication by single mutations in the 3' region of Moloney murine leukemia virus reverse transcriptase

1989 • 74 citations

RNase H-defective mutants of Escherichia coli: A possible discriminatory role of RNase H in initiation of DNA replication

1984 • 67 citations

Overproduction and preliminary crystallographic study of ribonuclease H from Escherichia coli

1989 • 61 citations

Isolation and mapping of a mutation in Escherichia coli with altered levels of ribonuclease H

1980 • 55 citations

Initiation of plus-strand DNA synthesis during reverse transcription of an avian retrovirus genome

1984 • 53 citations

Selective inhibition of RNase H by dextran.

1981 • 42 citations

The rnh gene is essential for growth of Escherichia coli.

1984 • 40 citations

Calf thymus ribonuclease specific for ribonucleic acid-deoxyribonucleic acid hybrids

1973 • 39 citations

Improvement of limit of diffraction and useful X-ray lifetime of crystals of glycogen debranching enzyme

1986 • 30 citations

Model RNA-directed DNA synthesis by avian myeloblastosis virus DNA polymerase and its associated RNase H

1979 • 24 citations

Overview of phasing by isomorphous replacement

1985 • 10 citations

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