Growth hormone regulates the abundance of insulin-like growth factor I RNA in adult rat liver.

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action.

1984 • 1,171 citations

Actions of Insulin-Like Growth Factors

1985 • 1,141 citations

Insulin-like growth factor I stimulates growth in hypophysectomized rats

1982 • 605 citations

Radioimmunological determination of insulinlike growth factors I and II in normal subjects and in patients with growth disorders and extrapancreatic tumor hypoglycemia.

1981 • 595 citations

Synthesis and Secretion of Insulin-Like Growth Factor and Its Binding Protein by the Perfused Rat Liver: Dependence on Growth Hormone Status^*

1983 • 447 citations

Evidence that somatomedin is synthesized by multiple tissues in the fetus

1980 • 434 citations

Hormonal Proteins and Peptides

1979 • 428 citations

Sequence of cDNA encoding human insulin-like growth factor I precursor

1983 • 401 citations

Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides.

1986 • 371 citations

Increased levels of multiplication-stimulating activity, an insulin-like growth factor, in fetal rat serum.

1980 • 313 citations

6 Factors controlling blood concentration of somatomedin C

1984 • 299 citations

Developmental patterns of insulin-like growth factor-I and -II synthesis and regulation in rat fibroblasts

1983 • 269 citations

Human chromosomal mapping of genes for insulin-like growth factors I and II and epidermal growth factor

1984 • 267 citations

Two insulin-like growth factor I messenger RNAs are expressed in human liver.

1986 • 260 citations

PRODUCTION OF INSULIN-LIKE GROWTH FACTORS BY OVARIAN GRANULOSA CELLS

1985 • 213 citations

Isolation of the human insulin-like growth factor genes: insulin-like growth factor II and insulin genes are contiguous.

1985 • 212 citations

Localization of insulin-like growth factor genes to human chromosomes 11 and 12

1984 • 180 citations

A rapid, inexpensive, quantitative technique for the analysis of two-dimensional electrophoretograms

1982 • 158 citations

Developmental and tissue-specific expression of a family of transcripts related to rat insulin-like growth factor II mRNA

1985 • 155 citations

Production of Insulin-Like Growth Factor I and Its Binding Protein by Adult Rat Hepatocytes in Primary Culture*

1985 • 115 citations

Isolation of a cDNA clone encoding rat insulin-like growth factor-II precursor

1984 • 105 citations

Interactions of thyroid hormone, growth hormone, and high carbohydrate, fat-free diet in regulating several rat liver mRNA species

1983 • 102 citations

Characterization of a somatomedin (insulin-like growth factor) synthesized by fetal rat liver organ cultures.

1979 • 100 citations

5 Somatomedin levels in childhood, adolescence and adult life

1984 • 92 citations

Rat Hepatocyte Insulin-Like Growth Factor I and Binding Protein: Effect of Growth Hormonein Vitroandin Vivo*

1985 • 91 citations

Isolation and Partial Sequence Analysis of Rat Basic Somatomedin*

1982 • 87 citations

Coordinate developmental regulation of high and low molecular weight mRNAs for rat insulin-like growth factor II.

1986 • 77 citations

Neonatal Rat Islet Cell Cultures Synthesize Insulin-like Growth Factor I

1985 • 65 citations

Developmental and hormonal regulation of alpha 2u-globulin gene transcription.

1985 • 59 citations

Serum Levels of Immunoreactive Somatomedin A in the Rat: Some Developmental Aspects*

1980 • 53 citations

HUNAN GROWTH HORMONE INDUCES AND MAINTAINS C-MYC GENE EXPRESSION IN ND2 LYMPHOMA CELLS

1985 • 52 citations

Fetal Rat Myoblasts Release Both Rat Somatomedin-C (SM-C)/Insulin-Like Growth Factor I (IGF I) and Multiplication-Stimulating Activityin Vitro: Partial Characterization and Biological Activity of Myoblast-Derived SM-C/IGF I*

1985 • 47 citations

Cell-Free Translation of Messenger RNAs from Human Muscle Biopsies: a Miniaturized Tool for Investigation of Neuromuscular Diseases

1982 • 36 citations

Growth hormone acts at a pretranslational level in hepatocyte cultures

1983 • 15 citations