Cyclic Nucleotide Phosphodiesterases

On the nature of allosteric transitions: A plausible model

1965 • 8,699 citations

Adenosine 3‘,5‘-Phosphate in Biological Materials

1962 • 2,102 citations

FRACTIONATION AND CHARACTERIZATION OF A CYCLIC ADENINE RIBONUCLEOTIDE FORMED BY TISSUE PARTICLES

1958 • 1,055 citations

Multiple cyclic nucleotide phosphodiesterase activities from rat brain

1971 • 1,054 citations

Cyclic 3′,5′-nucleotide phosphodiesterase

1970 • 824 citations

Microtechnical Demonstration of Phosphatase in Tissue Sections.

1939 • 750 citations

Membrane formation in Tetrahymena pyriformis. 4. Lipid composition and biochemical properties of Tetrahymena pyriformis membrane systems

1971 • 674 citations

Calcium dependent phosphodiesterase activity and its activating factor (PAF) from brain

1970 • 491 citations

Conformational transition accompanying the binding of calcium(2+) ion to the protein activator of 3',5'-cyclic adenosine monophosphate phosphodiesterase

1977 • 472 citations

Purification of cyclic 3',5'-nucleotide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to sepharose

1978 • 463 citations

Mechanism of Activation of a Cyclic Adenosine 3′:5′-Monophosphate Phosphodiesterase from Bovine Heart by Calcium Ions

1973 • 444 citations

Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster

1981 • 444 citations

Cyclic 3′ : 5′-Nucleotide Phosphodiesterase

1974 • 381 citations

Selective binding of antipsychotics and other psychoactive agents to the calcium-dependent activator of cyclic nucleotide phosphodiesterase.

1979 • 378 citations

Generation by Insulin of a Chemical Mediator That Controls Protein Phosphorylation and Dephosphorylation

1979 • 373 citations

Assay of adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate in biological materials by enzymic radioisotopic displacement

1968 • 369 citations

Effect of Insulin on Adenosine 3‘,5‘-Monophosphate in the Rat Epididymal Fat Pad

1966 • 340 citations

Subcellular Distribution of Adenyl Cyclase and Cyclic Phosphodiesterase in Rat Brain Cortex

1967 • 337 citations

Role of Adenosine 3′,5′-Monophosphate in the Effects of Insulin and Anti-insulin Serum on Liver Metabolism

1968 • 328 citations

Hydrolysis of Cyclic Guanosine and Adenosine 3',5'-Monophosphates by Rat and Bovine Tissues

1970 • 303 citations

Cyclic Nucleotides in the Nervous System

1977 • 297 citations

Characterization of Cyclic Nucleotide Phosphodiesterases of Rat Tissues

1971 • 297 citations

Properties of Cyclic 3',5'-Nucleotide Phosphodiesterase from Rat Brain^*

1967 • 297 citations

Stimulation of Adenosine 3',5'-Monophosphate Hydrolysis by Guanosine 3',5'-Monophosphate

1971 • 275 citations

An Effect of Insulin on Cyclic Adenosine 3′:5′-Monophosphate Phosphodiesterase Activity in Fat Cells

1973 • 245 citations

Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme.

1979 • 244 citations

Separate Phosphodiesterases for the Hydrolysis of Cyclic Adenosine 3′,5′-Monophosphate and Cyclic Guanosine 3′,5′-Monophosphate in Rat Liver

1973 • 230 citations

Pyruvate Dehydrogenase Activation in Adipocyte Mitochondria by an Insulin-Generated Mediator from Muscle

1979 • 222 citations

4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone (ZK 62711): a potent inhibitor of adenosine cyclic 3',5'-monophosphate phosphodiesterases in homogenates and tissue slices from rat brain.

1976 • 222 citations

Presence of calmodulin in postsynaptic densities isolated from canine cerebral cortex.

1979 • 208 citations

Stimulation of a low Km phosphodiesterase from liver by insulin and glucagon.

1978 • 208 citations

Specificity of the binding of trifluoperazine to the calcium-dependent activator of phosphodiesterase and to a series of other calcium-binding proteins

1978 • 207 citations

Cyclic Adenosine Monophosphate Phosphodiesterase in Brain: Effect on Anxiety

1972 • 207 citations

Enzymatic Hydrolysis of Adenosine 3',5'-Phosphoric Acid

1961 • 206 citations

Cyclic Nucleotide Phosphodiesterases: Properties, Activators, Inhibitors, Structure–Activity Relationships, and Possible Role in Drug Development

1975 • 206 citations

Insulin-sensitive phosphodiesterase. Its localization, hormonal stimulation, and oxidative stabilization.

1975 • 203 citations

Cyclic 3′,5′-nucleotide phosphodiesterase. Distribution and developmental changes of the enzyme and its protein activator in mammalian tissues and cells

1974 • 198 citations

[30] Assay of cyclic nucleotide phosphodiesterases with radioactive substrates

1974 • 184 citations

Actions of insulin in fat cells. Effects of low temperature, uncouplers of oxidative phosphorylation, and respiratory inhibitors.

1977 • 175 citations

A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes

1980 • 174 citations

Prostaglandin E ₁ Effects on Adenosine 3′:5′-Cyclic Monophosphate Concentration and Phosphodiesterase Activity in Fibroblasts

1972 • 167 citations

Effect of Insulin and Lipolytic Agents on Rat Adipocyte Low K Cyclic Adenosine 3′ : 5′-Monophosphate Phosphodiesterase

1974 • 165 citations

Cyclic AMP-Dependent Protein Kinase: Pivotal Role in Regulation of Enzyme Induction and Growth

1975 • 164 citations

Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from diabetic rats☆

1974 • 163 citations

Regional and subcellular distribution of adenyl cyclase and 3',5'-cyclic nucleotide phosphodiesterase in brain and pineal gland

1968 • 161 citations

Cyclic 3′,5′-Nucleotide Phosphodiesterase: Cytochemical Localization in Cerebral Cortex

1971 • 159 citations

Purification and properties of bovine brain calmodulin-dependent cyclic nucleotide phosphodiesterase.

1980 • 157 citations

Separation of multiple molecular forms of cyclic adenosine-3′,5′-monophosphate phosphodiesterase in rat cerebellum by polyacrylamide gel electrophoresis

1972 • 156 citations

Purification and Properties of 3',5'-Cyclic Nucleotide Phosphodiesterase from Dog Heart^*

1966 • 154 citations

Lac Operator Analogues: Bromodeoxyuridine Substitution in the lac Operator Affects the Rate of Dissociation of the lac Repressor

1972 • 153 citations

Insulin triggers cyclic AMP-dependent activation and phosphorylation of a plasma membrane cyclic AMP phosphodiesterase

1980 • 149 citations

Human blood platelet 3′:5′-cyclic nucleotide phosphodiesterase

1976 • 146 citations

Regulation of Nucleoside Cyclic 3′:5′-Monophosphate Phosphodiesterase Activity from Rat Brain by a Modulator and Ca ²⁺

1973 • 142 citations

Regulation of Adenosine 3′:5′-Cyclic Monophosphate Phosphodiesterase Activity in Fibroblasts by Intracellular Concentrations of Cyclic Adenosine Monophosphate

1972 • 141 citations

Effects of retinal ablation on uptake of glutamate, glycine, GABA, proline and choline in pigeon tectum.

1976 • 134 citations

Calcium-binding phosphoprotein from pig brain: Identification as a calcium-dependent regulator of brain cyclic nucleotide phosphodiesterase

1974 • 125 citations

Selective Alteration of the Activity of the Multiple Forms of Adenosine 3', 5'-Monophosphate Phosphodiesterase of Rat Cerebrum

1974 • 116 citations

Isolation of a Plasma‐Membrane Subfraction from Rat Liver Containing an Insulin‐Sensitive Cyclic‐AMP Phosphodiesterase

1972 • 113 citations

Affinity chromatography purification of a cyclic nucleotide phosphodiesterase using immobilized modulator protein, a troponin C-like protein from brain

1976 • 112 citations

Cyclic nucleotide phosphodiesterases and thyroid hormones.

1975 • 110 citations

Insulin action on the adenyl cyclase system: Antagonism to activation by lipolytic hormones

1972 • 109 citations

Enzymatic regulation of the concentration of cyclic GMP in mouse brain

1978 • 106 citations

The specific interaction of Cibacron and related dyes with cyclic nucleotide phosphodiesterase and lactate dehydrogenase

1978 • 106 citations

Effects of Thyroid Hormone Deficiency on Cyclic Adenosine 3′ : 5′-Monophosphate and Control of Lipolysis in Fat Cells

1974 • 103 citations

Purification of a cyclic nucleotide phosphodiesterase from bovine brain using blue dextran-Sepharose chromatography.

1979 • 101 citations

Purification and properties of the insulin-stimulated cyclic AMP phosphodiesterase from rat liver plasma membranes

1981 • 100 citations

Cyclic Nucleotide Phosphodiesterases

2008 • 98 citations

Regulation of Phosphodiesterase Synthesis: Requirement for Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1973 • 93 citations

Cyclic 3′,5′-Nucleotide Phosphodiesterase: Localization and Latent Activity in Rat Brain

1967 • 91 citations

Phosphodiesterases from porcine coronary arteries: inhibition of separated forms by xanthines, papaverine, and cyclic nucleotides.

1975 • 91 citations

Inhibition of cyclic 3′,5′-nucleotide phosphodiesterase by phenothiazine and reserpine derivatives

1968 • 90 citations

Cyclid 3':5'-nucleotide phosphodiesterase. Interconvertible multiple forms and their effects on enzyme activity and kinetics.

1976 • 86 citations

Cyclic GMP stimulation and inhibition of cyclic AMP phosphodiesterase from thymic lymphocytes

1971 • 85 citations

Flavonoids are selective cyclic GMP phosphodiesterase inhibitors

1979 • 83 citations

ONTOGENETIC DEVELOPMENT OF ADENYL CYCLASE AND PHOSPHODIESTERASE IN RAT BRAIN

1971 • 82 citations

Purification and characterization of high-affinity cyclic adenosine monophosphate phosphodiesterase from dog kidney

1979 • 81 citations

Properties of a phosphodiesterase with high affinity for adenosine 3',5'-cyclic phosphate

1971 • 79 citations

Interaction of 125I-labeled Ca2+-dependent regulator protein with cyclic nucleotide phosphodiesterase and its inhibitory protein.

1978 • 79 citations

Cyclic nucleotide phosphodiesterases in neoplastic and nonneoplastic human mammary tissues.

1976 • 79 citations

Cyclic AMP Phosphodiesterase in Cloned Astrocytoma Cells: Norepinephrine Induces a Specific Enzyme Form

1973 • 78 citations

Effect of insulin and growth hormone on rat liver cyclic nucleotide phosphodiesterase

1973 • 76 citations

INFLUENCE OF DIVALENT CATIONS ON REGULATION OF CYCLIC GMP AND CYCLIC AMP LEVELS IN BRAIN TISSUE

1976 • 76 citations

CYCLIC 3',5'-NUCLEOTIDE PHOSPHODIESTERASE IN BRAIN

1969 • 74 citations

Inhibitory and activators of cyclic nucleotide phosphodiesterase.

1976 • 73 citations

Effect of Insulin and Lipolytic Hormones on Cyclic AMP Phosphodiesterase Activity in Normal and Diabetic Rat Adipose Tissue

1975 • 71 citations

The role of cyclic GMP in the regulation of cyclic AMP hydrolysis

1975 • 69 citations

Effects of glucocorticoids and insulin on 3?,5?-AMP phosphodiesterase activity in adrenalectomized rats

1968 • 66 citations

3′:5′-Cyclic Adenosine Monophosphate Phosphodiesterase: Negative Cooperativity

1972 • 66 citations

Cyclic Nucleotides in Disease

1976 • 65 citations

Histochemical method for localization of cyclic 3?, 5?-nucleotide phosphodiesterase

1966 • 64 citations

Guanylate cyclase and cyclic guanosine 3':5'-monophosphate phosphodiesterase activities and cyclic guanosine 3':5'-monophosphate levels in normal and transformed fibroblasts in culture.

1976 • 64 citations

Cyclic Adenosine 3′:5′-Monophosphate and Cyclic Guanosine 3′:5′-Monophosphate Phosphodiesterase Activities Are under Separate Genetic Control

1974 • 63 citations

Cyclic nucleotide phosphodiesterase activities from isolated fat cells: Correlation of subcellular distribution with effects of nucleotides and insulin

1974 • 62 citations

Structure-activity relationships for inhibitors of phosphodiesterase from erythrocytes and other tissues.

1972 • 61 citations

Regulation of transsynaptically elicited increase of 3':5'-cyclic AMP by endogenous phosphodiesterase activator.

1976 • 60 citations

Proteolytic solubilization and modification of hormone-sensitive cyclic nucleotide phosphodiesterase.

1980 • 59 citations

Plasma Membrane Cyclic Adenosine 3′:5′-Monophosphate Phosphodiesterase of Cultured Cells and Its Modification after Trypsin Treatment of Intact Cells

1973 • 58 citations

Molecular Mechanisms of Cyclic AMP Action: A Genetic Approach

1976 • 57 citations

Substrate and effector specificity of a guanosine 3':5'-monophosphate phosphodiesterase from rat liver.

1977 • 56 citations

REGIONAL, CELLULAR AND SUBCELLULAR DISTRIBUTION OF CALCIUM‐ACTIVATED CYCLIC NUCLEOTIDE PHOSPHODIESTERASE AND CALCIUM‐DEPENDENT REGULATOR IN PORCINE BRAIN¹

1977 • 54 citations

Cytidine 3‘:5‘-monophosphate phosphodiesterase in mammalian tissues. Occurrence and biological involvement.

1978 • 53 citations

Cytidylate cyclase: The product isolated by the method of Cech and Ignarro is not cytidine 3′,5′-monophosphate

1979 • 52 citations

Separation of multiple forms of cyclic nucleotide phosphodiesterases from rat brain by isoelectrofocusing

1974 • 51 citations

Regulation of cyclic nucleotide phosphodiesterase.

1975 • 50 citations

Two forms of Ca2+-dependent cyclic 3′:5′-nucleotide phosphodiesterase from human aorta and effect of free fatty acids

1978 • 48 citations

ONTOGENETIC DEVELOPMENT OF A PHOSPHODIESTERASE ACTIVATOR AND THE MULTIPLE FORMS OF CYCLIC AMP PHOSPHODIESTERASE OF RAT BRAIN

1974 • 47 citations

Isolation and Regulation of the Protein Kinase Inhibitor and the Calcium-Dependent Cyclic Nucleotide Phosphodiesterase Regulator in the Sertoli Cell-Enriched Testis¹

1977 • 45 citations

Release of enzymes from a rat liver lysosome fraction: inhibition by catecholamines and cyclic3', 5'-adenosine monophosphate, stimulation by cholinergic agents and cyclic 3', 5'-guanosine monophosphate.

1973 • 44 citations

In vitro inhibition of cyclic AMP phosphodiesterase by cortisol

1976 • 43 citations

Regulation of cyclic nucleotide phosphodiesterases in cultured hepatoma cells by dexamethasone and N6,O2'-dibutyryl adenosine 3':k'-monophosphate.

1977 • 42 citations

Influence of cyclic guanosine-3?,5?-monophosphate on the enzymatic hydrolysis of adenosine-3?,5?-monophosphate

1972 • 42 citations

Quantitative estimation of 3′5′ cyclic AMP phosphodiesterase using anion exchange resin in a batch process

1976 • 41 citations

Stimulation of cyclic nucleotide phosphodiesterases from rat brain by activator protein, proteolytic enzymes and a vitamin E derivative

1977 • 40 citations

The organization of paramembranous densities during postnatal maturation of synaptic junctions in the cerebral cortex

1972 • 40 citations

Neonatal development of rat kidney adenyl cyclase and phosphodiesterase

1972 • 39 citations

Cytochemical localization of cyclic nucleotide phosphodiesterase activity at developing synapses

1974 • 39 citations

Multiple forms of cyclic nucleotide phosphodiesterase in pig epidermis

1976 • 39 citations

Ontogenetic changes in levels of phosphodiesterase for adenosine 3′:5′-monophosphate and guanosine 3′:5′-monophosphate in the lung, liver, brain and heart from guinea pigs

1976 • 38 citations

Effect of cyclic nucleotides on activity of cyclic 3′,5′-adenosine monophosphate phosphodiesterase

1973 • 38 citations

Demonstration, in leukemia L-1210 cells, of a phosphodiesterase acting on 3':5'-cyclic CMP but not on 3':5'-cyclic AMP or 3':5'-cyclic GMP.

1978 • 38 citations

Purification and properties of cyclic AMP phosphodiesterase from rat brain

1972 • 38 citations

Changes of the activities of adenyl cyclase and cAMP-phosphodiesterase and of the level of 3′5′ cyclic adenosine monophosphate in rat mammary gland during pregnancy and lactation

1973 • 37 citations

Increased cyclic nucleotide phosphodiesterase activity in leukaemic lymphocytes

1976 • 36 citations

An effect of glucagon on 3′,5′-cyclic AMP phosphodiesterase activity in isolated rat hepatocytes

1975 • 35 citations

A CYTOGENETIC ANALYSIS OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ACTIVITIES IN DROSOPHILA

1977 • 35 citations

Cyclic 3′,5′-nucleotide phosphodiesterase in nerve endings of developing rat brain

1971 • 34 citations

Mode of Action of N6-O2′-Dibutyryl Cyclic 3′, 5′ AMP on Fat Cell Metabolism

1974 • 33 citations

Activation of mammalian cyclic AMP phosphodiesterases by trypsin

1978 • 33 citations

Activation of cyclic nucleotide phosphodiesterase from isolated human peripheral blood lymphocytes by mitogenic agents.

1980 • 33 citations

Increased cyclic nucleotide phosphodiesterase activity associated with proliferation and cancer in human and murine lymphoid cells.

1977 • 32 citations

Biochemical characterization of postsynaptically localized cyclic nucleotide phosphodiesterase

1979 • 31 citations

Calcium-dependent 3‘:5‘-cyclic nucleotide phosphodiesterase. Inhibition of basal activity at physiological levels of potassium ions.

1978 • 31 citations

Differential activation and inhibition of the multiple forms of cyclic nucleotide phosphodiesterase.

1975 • 31 citations

Regional Cyclic Nucleotide Phosphodiesterase Activity in Cat Central Nervous System: Effects of Benzodiazepines

1974 • 30 citations

Characterization of cyclic nucleotide phosphodiesterases with multiple separation techniques

1976 • 30 citations

Characteristics of the cyclic nucleotide phosphodiesterases of normal and leukemic lymphocytes

1977 • 29 citations

Inhibition of metabolic effects of growth hormone by various inhibitors of cyclic nucleotide phosphodiesterase

1973 • 29 citations

Increased activity of cyclic AMP phosphodiesterase from frozen-thawed rat liver. A role of lysosomal protease in enzyme activation

1978 • 28 citations

Rat mast cell high affinity cyclic nucleotide phosphodiesterases: separation and inhibitory effects of two antiallergic agents.

1978 • 28 citations

Multiple forms of cyclic adenosine 3′,5′-monophosphate phosphodiesterase from human blood platelets. I. Kinetic and electrophoretic characterization of two molecular species

1973 • 27 citations

Characterization of an adenosine 3′:5′-cyclic monophosphate phosphodiesterase from baker's yeast. Its binding to subcellular particles, catalytic properties and gel-filtration behaviour

1977 • 27 citations

Cyclic Nucleotide Phosphodiesterase Activity in Human Peripheral Blood Lymphocytes and Monocytes

1979 • 27 citations

A kinetic analysis of the cyclic nucleotide phosphodiesterase regulation by the endogenous protein activator A study of rat brain and frog sympathetic chain

1976 • 27 citations

Inhibition of Glucagon-Mediated Increases in Hepatic Cyclic Adenosine 3',5'-Monophosphate by Prostaglandin E₁and E₂

1974 • 25 citations

Purification of calcium-dependent phosphodiesterases from rat cerebrum by affinity chromatography on activator protein-sepharose

1977 • 24 citations

Cyclic 3',5'-nucleotide phosphodiesterases of Novikoff rat hepatoma, mouse L, and HeLa cells growing in suspension culture.

1972 • 23 citations

REGULATION OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASES OF CEREBRAL CORTEX BY Ca²⁺AND CYCLIC GMP

1978 • 23 citations

Partial purification and characterization of cyclic nucleotide phosphodiesterases from human bronchial tissue

1978 • 23 citations

Responsiveness to glucagon by isolated rat hepatocytes controlled by the redox state of the cytosolic nicotinamide—adenine dinucleotide couple acting on adenosine 3′:5′-cyclic monophosphate phosphodiesterase

1978 • 23 citations

THE CONSEQUENCES OF NULLOSOMY FOR A CHROMOSOMAL REGION AFFECTING CYCLIC AMP PHOSPHODIESTERASE ACTIVITY IN DROSOPHILA

1977 • 23 citations

Cyclic guanosine 3′,5′-monophosphate and phosphodiesterase activity in mitogen-stimulated human lymphocytes

1979 • 22 citations

Cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in malignant and cyclic adenosine 3':5'-monophosphate-induced "differentiated" neuroblastoma cells.

1975 • 22 citations

Subcellular localization of cyclic nucleotide phosphodiesterase in the caudate nucleus

1977 • 22 citations

Cyclic 3',5'-nucleotide monophosphate phosphodiesterase activity in hepatomas of different growth rates.

1972 • 21 citations

Effect of Diabetes and Insulin on the Rat Heart Adenyl Cyclase, Cyclic AMP Phosphodiesterase and Cyclic AMP

1973 • 20 citations

Phosphodiesterase activator from rat kidney cortex.

1978 • 20 citations

The role of cyclic AMP in slime mold development

1974 • 20 citations

Effects of CuCl2 on the hydrolysis of cyclic GMP and cyclic AMP by the activator-dependent cyclic nucleotide phosphodiesterase from bovine heart

1978 • 20 citations

Cytidine 3′,5′-Monophosphate Phosphodiesterase: Decreased Activity in the Regenerating and Developing Liver

1978 • 20 citations

Ca-2+/Mg-2+-dependent cyclic nucleotide phosphodiesterase and its activator protein.

1975 • 20 citations

Histochemical evidence of cyclic nucleotide phosphodiesterase in photoreceptor outer segments.

1974 • 19 citations

Cyclic nucleotide phosphodiesterase activity in the plasma and erythrocytes of normal and diabetic rats

1973 • 19 citations

Depression of cytidine 3':5'-cyclic monophosphate phosphodiesterase activity in developing tissues of guinea pigs.

1978 • 19 citations

Effects of Nicotinic Acid and Some of its Homologues on Lipolysis, Adenyl Cyclase, Phosphodiesterase and Cyclic AMP Accumulation in Isolated Fat Cells

1971 • 19 citations

Cyclic Nucleotide Phosphodiesterases from Rat Anterior Pituitary. Characterization of Multiple Forms and Regulation by Protein Activator and Ca2+

1977 • 19 citations

Genetic manipulation of cyclic AMP levels in Drosophila,melanogaster

1978 • 19 citations

Solubilization and characterization of hormone-responsive phosphodiesterase activity of rat fat cells

1977 • 19 citations

Effects of FSH on Cyclic Nucleotide Accumulation in Testes of Rats of Various Ages

1977 • 18 citations

Alpha-Amanitin Administration Results in a Temporary Inhibition of Hepatic Enzyme Induction by Triiodothyronine: Further Evidence Favoring a Long-Lived Mediator of Thyroid Hormone Action

1977 • 18 citations

Kinetic and electrophoretic abnormality of cyclic AMP phosphodiesterase in genetically obese mouse adipocytes

1973 • 18 citations

Insulin-sensitive adenosine 3′,5′-cyclic monophosphate phosphodiesterase of hepatocyte plasma membrane

1977 • 18 citations

Inhibition of 3′,5′-nucleotide phosphodiesterase in guinea pig cerebral cortical slices

1974 • 18 citations

Cyclic nucleotide phosphodiesterase and protein activator in fetal rabbit tissues

1978 • 17 citations

Separation of three cyclic-nucleotide-phosphodiesterases from bovine aorta

1978 • 17 citations

Distribution and regulation of the phosphodiesterases of muscle tissues.

1978 • 17 citations

Hormonal Regulation of Cyclic Nucleotide Phosphodiesterases

1978 • 17 citations

Cyclic 3',5'-nucleotide phosphodiesterase; cytochemical localization in rat renomedullary interstitial cells.

1978 • 16 citations

Adenylate cyclase and cyclic nucleotide phosphodiesterases in the developing rat liver

1977 • 16 citations

Cytochemical localization of cyclic 3′,5′-nucleotide phosphodiesterase activity in the neuromuscular junction and skeletal muscle of the newt

1976 • 16 citations

Cyclic Nucleotide Phosphodiesterase: Insulin Activation Detected in Adipose Tissue by Gel Electrophoresis

1977 • 15 citations

Calcium and papaverine interaction with soluble cardiac phosphodiesterase

1975 • 15 citations

Cyclic nucleotide phosphodiesterase in silkworm

1975 • 14 citations

Effects of glucocorticoids on adenyl cyclase and phosphodiesterase activity in fat cell homogenates and the accumulation of cyclic AMP in intact fat cells

1972 • 14 citations

Cyclic 3′:5′-nucleotide phosphodiesterase of rabbit sinoatrial node

1978 • 13 citations

Stimulation by insulin of cyclic AMP phosphodiesterase. role of glutathione-insulin transhydrogenase

1977 • 13 citations

Cannabinoid effects on adenylate cyclase and phosphodiesterase activities of mouse brain

1977 • 13 citations

Eukaryotic cell function and growth : regulation by intracellular cyclic nucleotides

1976 • 13 citations

Lymphocyte Membrane Enzymes. II. Cyclic 3',5'-Adenosine Monophosphatase Located on Unstimulated Human Small Lymphocyte Nuclear Membranes

1971 • 13 citations

Characterization of soluble uterine cyclic nucleotide phosphodiesterase

1978 • 12 citations

Cyclic AMP phosphodiesterase in human lymphocytes and lymphoblasts.

1978 • 12 citations

Cyclic nucleotide phosphodiesterase in silkworm. Developmental change of cyclic AMP and cyclic GMP phosphodiesterases

1975 • 11 citations

Calcium-dependent cyclic nucleotide phosphodiesterase inhibition of basal activity by heat-stable factors from rat cerebrum

1979 • 11 citations

Cyclic nucleotide phosphodiesterases in uterine development

1975 • 11 citations

Cell cycle traverse and macromolecular synthesis in BHK fibroblasts as affected by insulin

1979 • 11 citations

Cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in normal and chronic lymphocytic leukemia lymphocytes.

1976 • 11 citations

Localization of 3?, 5?-cyclic nucleotide phosphodiesterase activity in isolated thyroid cells and intact thyroid tissue

1974 • 10 citations

Regulation of cyclic nucleotide phosphodiesterase forms by serum and insulin in cultured fibroblasts

1979 • 10 citations

Reciprocal changes in Ca2+protein activator-dependent and-independent cyclic AMP phosphodiesterase during the development of chick embryos

1976 • 10 citations

The effect of slow freezing and hypertonic NaCl on the hydrolytic activity of rat erythrocyte cyclic AMP phosphodiesterase and its sensitivity to the inhibitor, d,l-4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone

1974 • 10 citations

Multiple cyclic nucleotide phosphodiesterases in rat kidney

1975 • 9 citations

Regulation of cyclic nucleotide phosphodiesterase activity in human lung fibroblasts

1978 • 9 citations

Characteristics of the cyclic nucleotide phosphodiesterases in a transplantable pheochromocytoma and adrenal medulla of the rat.

1978 • 9 citations

Inhibitory effect of 8-substituted adenosine derivatives on Ca++ and modulator protein-dependent phosphodiesterase activity

1978 • 9 citations

Analyses of cyclic nucleotide phosphodiesterases in lymphocytes from normal and aged leukemic mice.

1978 • 8 citations

CYCLIC NUCLEOTIDE PHOSPHODIESTERASE IN RAT NEOSTRIATUM: PROPERTIES OF THE ENZYME IN CRUDE HOMOGENATES

1976 • 8 citations

The effects of nonsuppressible insulin-like protein (NSILP) on cyclic nucleotide metabolism in rat liver

1978 • 7 citations

Modified distribution of some cyclic AMP phosphodiesterase activities following growth of L cell fibroblasts in presence of prostaglandin E1

1972 • 7 citations

Thyrotropin Effect on Cyclic 3’, 5’ – Nucleotide Phosphodiesterase Intracellular Distribution

1974 • 6 citations

EFFECTS OF ATP ON THE ACTIVITY OF NUCLEOSIDE 3′,5′‐CYCLIC MONOPHOSPHATE PHOSPHODIESTERASE FROM BRAIN

1974 • 6 citations

Decreased adenosine cyclic 3',5'-monophosphate phosphodiesterase activity in rat straitum following chronic haloperidol treatment.

1977 • 6 citations

Effect of 5-bromodeoxyuridine on the induction of adenosine 3′:5′-monophosphate phosphodiesterase in 3T3-L fibroblasts

1978 • 5 citations

The effect of Ca++ on cyclic nucleotide phosphodiesterases of superior cervical ganglion.

1975 • 4 citations

THE DISTRIBUTION OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE IN THE HYPOTHALAMUS

1978 • 4 citations