Activation of mammalian cyclic AMP phosphodiesterases by trypsin

A simplified method for the quantitative assay of small amounts of protein in biologic material

1973 • 1,802 citations

Multiple cyclic nucleotide phosphodiesterase activities from rat brain

1971 • 1,054 citations

The Subunit Structure of Rabbit‐Skeletal‐Muscle Phosphorylase Kinase, and the Molecular Basis of Its Activation Reactions

1973 • 727 citations

Membrane formation in Tetrahymena pyriformis. 4. Lipid composition and biochemical properties of Tetrahymena pyriformis membrane systems

1971 • 674 citations

Cyclic 3',5'-Nucleotide Phosphodiesterase

1971 • 531 citations

Purification and Properties of the Protein Activator of Bovine Heart Cyclic Adenosine 3′,5′-Monophosphate Phosphodiesterase

1973 • 343 citations

Purification and properties of the light-activated cyclic nucleotide phosphodiesterase of rod outer segments

1975 • 271 citations

Modulator binding protein. Bovine brain protein exhibiting the Ca2+-dependent association with the protein modulator of cyclic nucleotide phosphodiesterase.

1977 • 252 citations

Separate Phosphodiesterases for the Hydrolysis of Cyclic Adenosine 3′,5′-Monophosphate and Cyclic Guanosine 3′,5′-Monophosphate in Rat Liver

1973 • 230 citations

Cyclic 3′,5′-nucleotide phosphodiesterase. Distribution and developmental changes of the enzyme and its protein activator in mammalian tissues and cells

1974 • 198 citations

Calcium-dependent cyclic nucleotide phosphodiesterase from brain: Identification of phospholipids as calcium-independent activators

1976 • 141 citations

Proteases as mitogens

1974 • 119 citations

Selective Alteration of the Activity of the Multiple Forms of Adenosine 3', 5'-Monophosphate Phosphodiesterase of Rat Cerebrum

1974 • 116 citations

Rapid microassay of adenosine 3′,5′-monophosphate phosphodiesterase activity

1972 • 98 citations

Cyclic adenosine 3':5'-monophosphate phosphodiesterase. Distinct forms in human lymphocytes and monocytes.

1976 • 90 citations

A proenzyme of cyclic nucleotide-independent protein kinase and its activation by calcium-dependent neutral protease from rat liver

1977 • 83 citations

Cyclic AMP Phosphodiesterase in Cloned Astrocytoma Cells: Norepinephrine Induces a Specific Enzyme Form

1973 • 78 citations

Effect of insulin and growth hormone on rat liver cyclic nucleotide phosphodiesterase

1973 • 76 citations

Cyclic 3':5'-nucleotide phosphodiesterase. Stimulation of bovine brain cytoplasmic enzyme by lysophosphatidylcholine.

1977 • 73 citations

The effect of nucleotides and a nondialyzable factor on the hydrolysis of cyclic AMP by a cyclic nucleotide phosphodiesterase from beef heart

1971 • 65 citations

Cyclic Adenosine 3′:5′-Monophosphate and Cyclic Guanosine 3′:5′-Monophosphate Phosphodiesterase Activities Are under Separate Genetic Control

1974 • 63 citations

Cyclic nucleotide phosphodiesterase activities from isolated fat cells: Correlation of subcellular distribution with effects of nucleotides and insulin

1974 • 62 citations

Calcium-dependent cyclic nucleotide phosphodiesterase from brain: Comparison of adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate as substrates

1976 • 60 citations

Multiple forms of Drosophila embryo DNA polymerase: evidence for proteolytic conversion

1977 • 59 citations

Plasma Membrane Cyclic Adenosine 3′:5′-Monophosphate Phosphodiesterase of Cultured Cells and Its Modification after Trypsin Treatment of Intact Cells

1973 • 58 citations

Activation of adenylate cyclase in cultured fibroblasts by trypsin.

1978 • 49 citations

ONTOGENETIC DEVELOPMENT OF A PHOSPHODIESTERASE ACTIVATOR AND THE MULTIPLE FORMS OF CYCLIC AMP PHOSPHODIESTERASE OF RAT BRAIN

1974 • 47 citations

Characterization of trypsin-treated forms of the estrogen receptor from rat and lamb uterus

1977 • 43 citations

Regulation of cyclic nucleotide phosphodiesterases in cultured hepatoma cells by dexamethasone and N6,O2'-dibutyryl adenosine 3':k'-monophosphate.

1977 • 42 citations

Stimulation of cyclic nucleotide phosphodiesterases from rat brain by activator protein, proteolytic enzymes and a vitamin E derivative

1977 • 40 citations

Purification and properties of cyclic AMP phosphodiesterase from rat brain

1972 • 38 citations

Limited proteolysis of nitrate reductase purified from membranes of Escherichia coli.

1977 • 38 citations

Increased cyclic nucleotide phosphodiesterase activity associated with proliferation and cancer in human and murine lymphoid cells.

1977 • 32 citations

Characterization of cyclic nucleotide phosphodiesterases with multiple separation techniques

1976 • 30 citations

Assay of cyclic nucleotide phosphodiesterase by a continuous titrimetric technique.

1974 • 28 citations

Partial purification and characterization of adenosine- and guanosine-3',5'-monophosphate phosphodiesterases from human lung tissue

1976 • 28 citations

Isolation of an activator of multiple forms of cyclic nucleotide phosphodiesterase of rat cerebrum by isoelectric focusing

1975 • 27 citations

Effect of andrenalectomy on cyclic 3′,5′-guanosine monophosphate metabolism of rat liver and other tissues

1974 • 26 citations

Partial purification of adenosine 3′,5′-cyclic monophosphate phosphodiesterases from rat pancreas in the presence of excess protease inhibitors

1976 • 23 citations

[33] Purification and characterization of cyclic 3′,5′-nucleotide phosphodiesterase from bovine brain

1974 • 22 citations

Trypsin-Induced Increase in Intracellular Cyclic AMP of Lymphocytes

1976 • 20 citations

Apparent multiple forms of cyclic AMP phosphodiesterase from rat erythrocytes

1976 • 16 citations

Characterization of soluble uterine cyclic nucleotide phosphodiesterase

1978 • 12 citations