Resolution, reconstitution and kinetics of the primary action of a hormone receptor

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 811 citations

Membrane Receptors

1974 • 636 citations

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

1976 • 623 citations

Membrane Receptors and Hormone Action

1976 • 484 citations

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

1978 • 480 citations

GTP-binding proteins in membranes and the control of adenylate cyclase activity.

1977 • 456 citations

Structural and Functional Properties of the Acetylcholine Receptor Protein in its Purified and Membrane-Bound States

1978 • 399 citations

Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.

1978 • 372 citations

Mode of coupling between the β-adrenergic receptor and adenylate cyclase in turkey erythrocytes

1978 • 347 citations

Molecular Basis of Insulin Action

1985 • 309 citations

Selection of a Variant Lymphoma Cell Deficient in Adenylate Cyclase

1975 • 276 citations

Fundamental difference between the molecular interactions of agonists and antagonists with the β-adrenergic receptor

1979 • 259 citations

Coupling of catecholamine receptor from one cell with adenylate cyclase from another cell by cell fusion.

1976 • 240 citations

Binding of (125I)iodohydroxybenzylpindolol to putative beta-adrenergic receptors of rat glioma cells and other cell clones.

1976 • 238 citations

Agonist-promoted coupling of the beta-adrenergic receptor with the guanine nucleotide regulatory protein of the adenylate cyclase system.

1980 • 229 citations

A persistent active state of the adenylate cyclase system produced by the combined actions of isoproterenol and guanylyl imidodiphosphate in frog erythrocyte membranes.

1975 • 221 citations

Mode of coupling between hormone receptors and adenylate cyclase elucidated by modulation of membrane fluidity

1978 • 202 citations

Fatty acids as modulators of membrane functions: catecholamine-activated adenylate cyclase of the turkey erythrocyte.

1975 • 187 citations

Reconstitution of catecholamine-sensitive adenylate cyclase. Reconstitution of the uncoupled variant of the S40 lymphoma cell.

1979 • 171 citations

A high affinity agonist . beta-adrenergic receptor complex is an intermediate for catecholamine stimulation of adenylate cyclase in turkey and frog erythrocyte membranes.

1980 • 152 citations

The role of the guanine nucleotide exchange reaction in the regulation of the beta-adrenergic receptor and in the actions of catecholamines and cholera toxin on adenylate cyclase in turkey erythrocyte membranes.

1980 • 126 citations

Isolation of adenylate cyclase-free, beta-adrenergic receptor from turkey erythrocyte membranes by affinity chromatography.

1977 • 104 citations

Transfer of glucagon receptor from liver membranes to a foreign adenylate cyclase by a membrane fusion procedure

1979 • 89 citations

The Binding of Reduced Nicotinamide Adenine Dinucleotide-Cytochrome b 5 Reductase to Hepatic Microsomes

1974 • 78 citations

Stimulus-Response Coupling at α-Adrenergic Receptors

1978 • 78 citations

Functional implantation of a solubilized β-adrenergic receptor in the membrane of a cell

1980 • 46 citations