The involvement of (NMDA) and non-NMDA receptors in the responsiveness of rat spinal neurons with input from the chronically inflamed ankle

Ethical guidelines for investigations of experimental pain in conscious animals

1983 • 7,639 citations

Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence

1993 • 2,006 citations

The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

1991 • 1,963 citations

Nociception from skeletal muscle in relation to clinical muscle pain

1993 • 833 citations

Afferent and spinal mechanisms of joint pain

1993 • 608 citations

The contribution of excitatory amino acids to central sensitization and persistent nociception after formalin-induced tissue injury

1992 • 564 citations

Evidence for spinal N-methyl-d-aspartate receptor involvement in prolonged chemical nociception in the rat

2016 • 516 citations

Evidence for spinalN-methyl-d-aspartate receptor involvement in prolonged chemical nociception in the rat

1990 • 458 citations

The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation

1992 • 422 citations

Expansion of receptive fields of spinal lamina I projection neurons in rats with unilateral adjuvant-induced inflammation: the contribution of dorsal horn mechanisms

1989 • 395 citations

The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli

1992 • 370 citations

Intrathecal MK-801 and local nerve anesthesia synergistically reduce nociceptive behaviors in rats with experimental peripheral mononeuropathy

1992 • 286 citations

MK-801 blocks the development of thermal hyperalgesia in a rat model of experimental painful neuropathy

1991 • 276 citations

Modulation of neuropathic pain behavior in rats by spinal disinhibition and NMDA receptor blockade of injury discharge

1991 • 236 citations

Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy

1992 • 236 citations

Evidence for a central component in the sensitization of spinal neurons with joint input during development of acute arthritis in cat's knee

1990 • 213 citations

N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint

1993 • 194 citations

Enhancement of the responses of ascending tract cells in the cat spinal cord by acute inflammation of the knee joint

1987 • 192 citations

Neural changes in acute arthritis in monkeys. I. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids

1992 • 161 citations

Electrophysiological characteristics of dorsal horn cells in rats with cutaneous inflammation resulting from chronic arthritis

1982 • 156 citations

Central neural mediators of secondary hyperalgesia following heat injury in rats: Neuropeptides and excitatory amino acids

1991 • 151 citations

Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model

1991 • 145 citations

The Effects of NMDA Antagonists on Neuronal Activity in Cat Spinal Cord Evoked by Acute Inflammation in the Knee Joint

1991 • 117 citations

Centrally administered non-NMDA but not NMDA receptor antagonists block peripheral knee joint inflammation

1993 • 113 citations

Dynamic changes in the receptive field properties of spinal cord neurons with ankle input in rats with chronic unilateral inflammation in the ankle region

1993 • 103 citations

An experimental arthritis model in rats: The effects of NMDA and non-NMDA antagonists on aspartate and glutamate release in the dorsal horn

1993 • 82 citations

Dorsal horn (convergent) neurones in the intact anaesthetized arthritic rat. I. Segmental excitatory influences

1987 • 73 citations

N-methyl-d-aspartate receptors mediate responses of rat dorsal horn neurones to hindlimb ischemia

1990 • 58 citations

Peripheral and spinal components of the sensitization of spinal neurons during an acute experimental arthritis

1988 • 55 citations

Differential effects of (NMDA) and non-NMDA receptor antagonists on the responses of rat spinal neurons with joint input

1993 • 47 citations