In a rat model of parkinsonism, lesions of the subthalamic nucleus reverse increases of reaction time but induce a dramatic premature responding deficit

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The functional anatomy of basal ganglia disorders

1989 • 5,166 citations

Primate models of movement disorders of basal ganglia origin

1990 • 3,722 citations

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Reversal of Experimental Parkinsonism by Lesions of the Subthalamic Nucleus

1990 • 1,875 citations

The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism

1994 • 1,352 citations

The organization of the projection from the cerebral cortex to the striatum in the rat

1989 • 1,334 citations

Adipsia and Aphagia after 6‐Hydroxydopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,271 citations

Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism

1991 • 641 citations

Reversal of Rigidity and Improvement in Motor Performance by Subthalamic High‐frequency Stimulation in MPTP‐treated Monkeys

1993 • 609 citations

Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1989 • 455 citations

The primate subthalamic nucleus. III. Changes in motor behavior and neuronal activity in the internal pallidum induced by subthalamic inactivation in the MPTP model of parkinsonism

1994 • 414 citations

Neurons of the subthalamic nucleus in primates display glutamate but not GABA immunoreactivity

1988 • 326 citations

Analysis of choreoid hyperkinesia in the rhesus monkey. Surgical and pharmacological analysis of hyperkinesia resulting from lesions in the subthalamic nucleus ol luys

1950 • 292 citations

Sensorimotor impairments following localized kainic acid and 6-hydroxydopamine lesions of the neostriatum

1982 • 289 citations

NMDA antagonists potentiate antiparkinsonian actions of <scp>L</scp>‐dopa in monoamine‐depleted rats

1990 • 285 citations

Primate models of dyskinesia: The experimental approach to the study of basal ganglia-related involuntary movement disorders

1987 • 276 citations

Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate

1991 • 201 citations

Depletion of dopamine in the caudate nucleus but not in nucleus accumbens impairs reaction-time performance in rats

1987 • 195 citations

Dopaminergic innervation of the basal ganglia in the squirrel monkey as revealed by tyrosine hydroxylase immunohistochemistry

1989 • 189 citations

Excitotoxic acid lesions of the primate subthalamic nucleus result in transient dyskinesias of the contralateral limbs

1992 • 172 citations

Organization of efferent projections of the subthalamic nucleus in the squirrel monkey as revealed by retrograde labeling methods

1987 • 154 citations

Excitotoxic acid lesions of the primate subthalamic nucleus result in reduced pallidal neuronal activity during active holding

1992 • 128 citations

Injection of excitatory amino acid antagonists into the medial pallidal segment of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treated primate reverses motor symptoms of parkinsonism

1990 • 116 citations

Dopaminergic mechanisms in subthalamic nucleus of rat: analysis using horseradish peroxidase and microiontophoresis

1985 • 109 citations

Characterization of the impaired feeding behavior in rats given haloperidol or dopamine-depleting brain lesions

1990 • 105 citations

Complex Deficits on Reaction Time Performance following Bilateral Intrastriatal 6‐OHDA Infusion in the Rat

1995 • 95 citations

Pharmacological characterization of dopaminergic influence on expression of neuropeptide Y immunoreactivity by rat striatal neurons

1988 • 93 citations

A Direct Role of Dopamine in the Rat Subthalamic Nucleus and an Adjacent Intrapeduncular Area

1979 • 90 citations

Somatosensory inputs to the subthalamic nucleus: a combined retrograde and anterograde horseradish peroxidase study in the rat

1988 • 80 citations

Dyskinesia in the primate following injection of an excitatory amino acid antagonist into the medial segment of the globus pallidus

1989 • 75 citations

The Effects of Activation or Inhibition of the Subthalamic Nucleus on the Metabolic and Electrophysiological Activities Within the Pallidal Complex and Substantia Nigra in the Rat

1991 • 69 citations

Dopamine and complex sensorimotor integration: Further studies in a conditioned motor task in the rat

1995 • 56 citations

The Connections of the Medial Part of the Subthalamic Nucleus in the Rat: Evidence for a Parallel Organization

1991 • 50 citations

Differential effect of subthalamic nucleus ablation on dopamine D1 and D2 agonist-induced rotation in 6-hydroxydopamine-lesioned rats

1992 • 38 citations

The Subthalamic Nucleus: New Data, New Questions

1991 • 28 citations

The Subthalamic Nucleus: A More Complex Structure than Expected

1994 • 12 citations

[Unilateral abolition of parkinsonian rigidity after subthalamic nucleus hemorrhage].

1992 • 11 citations

Intra-nigra infusion of AMPA attenuates dopamine-dependent rotation in the rat.

1993 • 10 citations