Immunocytochemical Localization of Ionotropic Glutamate Receptors (GluRs) in Neural Circuits

The structure of the nervous system of the nematodeCaenorhabditis elegans

1986 • 5,534 citations

Cloned Glutamate Receptors

1994 • 3,989 citations

The rat nervous system

1985 • 3,774 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

The Fine Structure of the Nervous System.

1970 • 1,971 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Glutamate-mediated astrocyte–neuron signalling

1994 • 1,688 citations

Ca2 ⁺ Permeability of KA-AMPA—Gated Glutamate Receptor Channels Depends on Subunit Composition

1991 • 1,458 citations

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

1994 • 1,342 citations

Excitatory amino acid receptors in the vertebrate central nervous system.

1989 • 1,316 citations

Cloning and characterization of chi-1: a developmentally regulated member of a novel class of the ionotropic glutamate receptor family

1995 • 1,252 citations

The Fine Structure of the Nervous System

1991 • 1,058 citations

Cloning by functional expression of a member of the glutamate receptor family

1989 • 1,009 citations

Protein Oligomerization in the Endoplasmic Reticulum

1989 • 993 citations

Light and electron immunocytochemical localization of AMPA‐selective glutamate receptors in the rat brain

1992 • 988 citations

Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.

1993 • 978 citations

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

1993 • 905 citations

The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels

1993 • 882 citations

From neuron to brain

1976 • 867 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons

1996 • 835 citations

D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release.

1995 • 823 citations

Comparison of Two Forms of Long-Term Potentiation in Single Hippocampal Neurons

1990 • 755 citations

Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

1993 • 736 citations

Metabotropic glutamate receptors: Synaptic transmission, modulation, and plasticity

1994 • 713 citations

Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

1995 • 669 citations

Differences in Ca2+ permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression

1994 • 661 citations

Protein degradation in the endoplasmic reticulum

1990 • 659 citations

A Molecular Determinant for Submillisecond Desensitization in Glutamate Receptors

1994 • 607 citations

The metabotropic glutamate receptors, MGLUR2 and MGLUR3, show unique postsynaptic, presynaptic and glial localizations

1996 • 584 citations

AMPA glutamate receptor subunits are differentially distributed in rat brain

1993 • 574 citations

Cellular localization of a metabotropic glutamate receptor in rat brain

1992 • 539 citations

Immunochemical characterization of the non-NMDA glutamate receptor using subunit-specific antibodies. Evidence for a hetero-oligomeric structure in rat brain.

1992 • 505 citations

The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1

1994 • 481 citations

Dynamic behavior of endoplasmic reticulum in living cells

1988 • 471 citations

A complex mosaic of high-affinity kainate receptors in rat brain

1993 • 464 citations

Differential expression of five N‐methyl‐D‐aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats

1994 • 463 citations

Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization

1994 • 420 citations

N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1

1994 • 419 citations

Organization of AMPA Receptor Subunits at a Glutamate Synapse: A Quantitative Immunogold Analysis of Hair Cell Synapses in the Rat Organ of Corti

1996 • 416 citations

Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain

1993 • 415 citations

Calcium-Permeable AMPA-Kainate Receptors in Fusiform Cerebellar Glial Cells

1992 • 413 citations

Developmental and regional expression pattern of a novel NMDA receptor- like subunit (NMDAR-L) in the rodent brain

1995 • 411 citations

Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone

1996 • 403 citations

Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin

1995 • 358 citations

Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn.

1994 • 356 citations

Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb

1993 • 355 citations

Subunit composition at the single-cell level explains functional properties of a glutamate-gated channel

1994 • 351 citations

Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system

1987 • 350 citations

The distribution of glutamate receptors in cultured rat hippocampal neurons: Postsynaptic clustering of AMPA selective subunits

1993 • 340 citations

Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus.

1994 • 339 citations

Calcium Entry Through Kainate Receptors and Resulting Potassium-Channel Blockade in Bergmann Glial Cells

1992 • 334 citations

A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb

1995 • 328 citations

Histological and ultrastructural localization of the kainate receptor subunits, KA2 and GluR6/7, in the rat nervous system using selective antipeptide antibodies

1994 • 325 citations

The differential expression patterns of messenger RNAs encoding non-N-methyl-d-aspartate glutamate receptor subunits (GluR1–4) in the rat brain

1993 • 304 citations

Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase

1993 • 294 citations

Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop

1995 • 293 citations

High-resolution immunogold localization of AMPA type glutamate receptor subunits at synaptic and non-synaptic sites in rat hippocampus

1995 • 292 citations

Selective Expression of the Glutamate Receptor Channel δ2 Subunit in Cerebellar Purkinje Cells

1993 • 287 citations

Differential Tyrosine Phosphorylation of N-Methyl-D-aspartate Receptor Subunits

1995 • 283 citations

Unraveling the modular design of glutamate-gated ion channels

1995 • 272 citations

Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices.

1992 • 272 citations

Cellular and subcellular localization of NMDA-R1 subunit immunoreactivity in the visual cortex of adult and neonatal rats

1994 • 250 citations

Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-trisphosphate receptor in rat brain

1993 • 249 citations

Biochemical Characterization and Localization of a Non‐N‐Methyl‐D‐Aspartate Glutamate Receptor in Rat Brain

1992 • 242 citations

Selective clustering of glutamate and gamma-aminobutyric acid receptors opposite terminals releasing the corresponding neurotransmitters.

1994 • 239 citations

Heterogeneity of synaptic glutamate receptors on CA3 stratum radiatum interneurones of rat hippocampus.

1993 • 226 citations

NMDA receptors and ligands in the vertebrate CNS

1988 • 226 citations

AMPA, KA and NMDA receptors are expressed in the rat DRG neurones

1993 • 214 citations

Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex

1994 • 210 citations

Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies

1996 • 208 citations

Pathway-specific variants of AMPA receptors and their contribution to neuronal signaling

1994 • 196 citations

Resolution and limitations of the immunoperoxidase procedure in the localization of extracellular matrix antigens.

1983 • 192 citations

Biochemical and immunocytochemical characterization of antipeptide antibodies to a cloned GluR1 glutamate receptor subunit: Cellular and subcellular distribution in the rat forebrain

1993 • 190 citations

The characterization and localization of the glutamate receptor subunit GluR1 in the rat brain

1991 • 189 citations

Region-specific expression of subunits of ionotropic glutamate receptors (AMPA-type, KA-type and NMDA receptors) in the rat spinal cord with special reference to nociception

1993 • 188 citations

An osmium-free method of epon embedment that preserves both ultrastructure and antigenicity for post-embedding immunocytochemistry.

1995 • 182 citations

AMPA receptors in the rat and primate hippocampus: a possible absence of GLUR2/3 subunits in most interneurons

1996 • 180 citations

Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation

1994 • 173 citations

Both NMDA and non-NMDA subtypes of glutamate receptors are concentrated at synapses on cerebral cortical neurons in culture

1991 • 172 citations

Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells.

1993 • 167 citations

Distribution and synaptic localization of immunocytochemically identified NMDA receptor subunit proteins in sensory-motor and visual cortices of monkey and human

1994 • 163 citations

Localization and developmental expression of the NMDA receptor subunit NR2A in the mammalian retina

1994 • 160 citations

Selective RNA editing and subunit assembly of native glutamate receptors

1994 • 158 citations

Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1.

1993 • 155 citations

Selective distribution of kainate receptor subunit immunoreactivity in monkey neocortex revealed by a monoclonal antibody that recognizes glutamate receptor subunits GluR5/6/7

1993 • 155 citations

Cellular and synaptic localization of NMDA and non-NMDA receptor subunits in neocortex: organizational features related to cortical circuitry, function and disease

1994 • 153 citations

Ionotropic and metabotropic glutamate receptors show unique postsynaptic, presynaptic, and glial localizations in the dorsal cochlear nucleus

1996 • 151 citations

Glutamate‐induced calcium signaling in astrocytes

1994 • 146 citations

Quantitative localization of AMPA/kainate and kainate glutamate receptor subunit immunoreactivity in neurochemically identified subpopulations of neurons in the prefrontal cortex of the macaque monkey

1993 • 146 citations

Neurotransmitter‐mediated signaling between axons and glial cells

1994 • 145 citations

Metabotropic Glutamate Receptors

2017 • 143 citations

Light and electron microscopic immunocytochemical localization of AMPA‐selective glutamate receptors in the rat spinal cord

1994 • 141 citations

Synaptic and nonsynaptic localization of the GluR1 subunit of the AMPA- type excitatory amino acid receptor in the rat cerebellum

1994 • 139 citations

Characterization of a Presynaptic Glutamate Receptor

1993 • 132 citations

Distribution of the excitatory amino acid receptor subunits GluR2(4) in monkey hippocampus and colocalization with subunits GluR5-7 and NMDAR1

1995 • 131 citations

Synaptic glutamate release by postnatal rat serotonergic neurons in microculture

1994 • 130 citations

Biochemical and assembly properties of GluR6 and KA2, two members of the kainate receptor family, determined with subunit-specific antibodies.

1994 • 122 citations

Subcellular localization of a putative kainate receptor in Bergmann glial cells using a monoclonal antibody in the chick and fish cerebellar cortex

1990 • 115 citations

Differential assembly of coexpressed glutamate receptor subunits in neurons of rat cerebral cortex

1994 • 108 citations

Tetanically induced LTP involves a similar increase in the AMPA and NMDA receptor components of the excitatory postsynaptic current: investigations of the involvement of mGlu receptors

1995 • 108 citations

Immunoprecipitation, immunoblotting, and immunocytochemistry studies suggest that glutamate receptor delta subunits form novel postsynaptic receptor complexes

1995 • 106 citations

Excitatory amino acid receptors in glial progenitor cells: Molecular and functional properties

1994 • 103 citations

Immunohistochemical visualization of a metabotropic glutamate receptor

1993 • 100 citations

Rapid Desensitization of the Metabotropic Glutamate Receptor that Facilitates Glutamate Release in Rat Cerebrocortical Nerve Terminals

1994 • 99 citations

Rectification Properties and Ca²⁺ Permeability of Glutamate Receptor Channels in Hippocampal Cells

1994 • 99 citations

Cellular localization and laminar distribution of AMPA glutamate receptor subunits mRNAs and proteins in the rat cerebral cortex

1994 • 98 citations

Cellular localizations of AMPA glutamate receptors within the basal forebrain magnocellular complex of rat and monkey

1993 • 96 citations

Properties of kainate receptor/channels on cultured Bergmann glia

1991 • 93 citations

N-Methyl-D-aspartate receptors are clustered and immobilized on dendrites of living cortical neurons.

1993 • 93 citations

Presynaptic depression of synaptic transmission mediated by activation of metabotropic glutamate receptors in rat neocortex

1994 • 91 citations

The striatal mosaic in primates: striosomes and matrix are differentially enriched in ionotropic glutamate receptor subunits

1993 • 83 citations

Localization of ampa-selective excitatory amino acid receptor subunits in identified populations of striatal neurons

1994 • 82 citations

Opioid receptors are involved in an NMDA receptor-independent mechanism of LTP induction at hippocampal mossy fiber-CA3 synapses

1991 • 81 citations

Presynaptic localization of a metabotropic glutamate receptor, mGluR4a, in the cerebellar cortex: a light and electron microscope study in the rat

1996 • 80 citations

Glutamate as a neuron-to-glial signal for mitogenesis: role of glialN-methyl-d-aspartate receptors

1993 • 78 citations

Localization of AMPA receptors in the hippocampus and cerebellum of the rat using an anti-receptor monoclonal antibody

1992 • 78 citations

Light- and electron-microscopic localization of the glutamate receptor channel 62 subunit in the mouse Purkinje cell

1995 • 77 citations

Localization of [3H]glutamate binding sites in rat adrenal medulla

1986 • 76 citations

Postsynaptic modifications in long-term facilitation in Aplysia: upregulation of excitatory amino acid receptors

1995 • 74 citations

Cyclothiazide unmasks AMPA‐evoked stimulation of [³H]‐L‐glutamate release from rat hippocampal synaptosomes

1994 • 72 citations

Glutamate receptor subunits at mossy fiber‐unipolar brush cell synapses: Light and electron microscopic immunocytochemical study in cerebellar cortex of rat and cat

1995 • 70 citations

Molecular Cloning and Differential Expression Patterns of Avian Glutamate Receptor mRNAs

1995 • 70 citations

Characterization of two alternatively spliced forms of a metabotropic glutamate receptor in the central nervous system of the rat

1994 • 69 citations

The segregation and expression of glutamate receptor subunits in cultured hippocampal neurons

1993 • 67 citations

A Possible Role of Glutathione as an Endogenous Agonist at the N‐Methyl‐<scp>d</scp>‐Aspartate Recognition Domain in Rat Brain

1995 • 67 citations

Immunological detection of glutamate receptor subtypes in human central nervous system

1992 • 66 citations

Regional and laminar differences in synaptic localization of NMDA receptor subunit NR1 splice variants in rat visual cortex and hippocampus

1996 • 64 citations

The Metabotropic Glutamate Receptors

1994 • 64 citations

Presynaptic localization of a metabotropic glutamate receptor, mGluR8, in the rhinencephalic areas: a light and electron microscope study in the rat

1996 • 63 citations

Complex pharmacological properties of recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subtypes.

1992 • 61 citations

GluR1-immunopositive interneurons in rat neocortex

1996 • 61 citations

Selected Methods for Antibody and Nucleic Acid Probes

1993 • 61 citations

Immunohistochemistry II

1994 • 60 citations

Immunocytochemical techniques: Principles and practice

1990 • 59 citations

Distribution of AMPA selective glutamate receptors in the thalamus of adult rats and during postnatal development. A light and ultrastructural immunocytochemical study

1994 • 59 citations

Immunocytochemical Techniques: Principles and Practice

1989 • 58 citations

Organization and quantitative analysis of kainate receptor subunit GluR5-7 immunoreactivity in monkey hippocampus

1993 • 51 citations

Membrane Topology of the GluR1 Glutamate Receptor Subunit: Epitope Mapping by Site‐Directed Antipeptide Antibodies

1994 • 50 citations

Kainate-binding proteins: phytogeny, structures and possible functions

1994 • 50 citations

Excitatory amino acids : their role in neuroendocrine function

1995 • 47 citations

DAB cytochemistry: artifact problems in its current uses.

1980 • 47 citations

Characteristic localization of non-NMDA type glutamate receptor subunits in the rat pituitary gland

1993 • 46 citations

The ampa glutamate receptor GluR3 is enriched in oxytocinergic magnocellular neurons and is localized at synapses

1995 • 45 citations

Glutamate metabotropic receptor activation in neonatal rat cerebral cortex by sulphur-containing excitatory amino acids

1993 • 44 citations

Moving off the beaten track

1992 • 42 citations

Distribution of AMPA-selective glutamate receptor subunits in the human hippocampus and cerebellum

1995 • 41 citations

Postnatal changes in NMDAR1 subunit expression in the rat trigeminal pathway to barrel field cortex

1996 • 37 citations

The Mammalian Cochlear Nuclei

1993 • 37 citations

Glutamate receptors in astrocytic end-feet

1994 • 36 citations

Excitatory Amino Acid Receptors in the Rat Cochlear Nucleus

1993 • 35 citations

Amino acid neurotransmission

1998 • 35 citations

Human peripheral monocytes express putative receptors for neuroexcitatory amino acids.

1986 • 34 citations

Comparative distribution of N‐Acetylaspartylglutamate and GAD₆₇ in the cerebellum and precerebellar nuclei of the rat utilizing enhanced carbodiimide fixation and immunohistochemistry

1994 • 32 citations

Distribution of a putative kainic acid receptor in the frog central nervous system determined with monoclonal and polyclonal antibodies: evidence for synaptic and extrasynaptic localization

1990 • 22 citations

Non‐NMDA glutamate receptors are present throughout the primate hypothalamus

1995 • 22 citations

Sympathetic and parasympathetic ganglia express non-NMDA type glutamate receptors: distinct receptor subunit composition in the principle and SIF cells

1993 • 17 citations

Identification and localization of a kainate binding protein in the frog inner ear by electron microscopy immunocytochemistry

1991 • 15 citations

Autoradiographic distribution of glutamatergic ligand binding sites inXenopus brain: evidence for intracellular [3H]AMPA binding sites

1993 • 6 citations

Amino Acid Neurotransmission

2004 • 3 citations