Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn.

The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

1991 • 1,963 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

A Comparative Study of the Peroxidase-antiperoxidase Method and an Avidin-Biotin Complex Method for Studying Polypeptide Hormones with Radioimmunoassay Antibodies

1981 • 1,664 citations

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

1994 • 1,342 citations

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

1992 • 1,088 citations

Cloning by functional expression of a member of the glutamate receptor family

1989 • 1,009 citations

Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation

1992 • 962 citations

Activity-dependent neuronal plasticity following tissue injury and inflammation

1992 • 933 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following c fibre stimulation.

1987 • 836 citations

Presynaptic enhancement shown by whole-cell recordings of long-term potentiation in hippocampal slices

1990 • 803 citations

Presynaptic mechanism for long-term potentiation in the hippocampus

1990 • 691 citations

Evidence for involvement ofN-methylaspartate receptors in ‘wind-up’ of class 2 neurones in the dorsal horn of the rat

1987 • 666 citations

Glutamate and substance P coexist in primary afferent terminals in the superficial laminae of spinal cord.

1988 • 580 citations

Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing

1992 • 521 citations

Long-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cord

1993 • 521 citations

The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray

1993 • 435 citations

Glutamate receptor channels in rat DRG neurons: Activation by kainate and quisqualate and blockade of desensitization by con A

1990 • 420 citations

Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain

1993 • 415 citations

Quantitative autoradiographic distribution of L-[3H]glutamate-binding sites in rat central nervous system

1984 • 353 citations

The sodium channel from rat brain. Purification and subunit composition.

1984 • 352 citations

Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C.

1993 • 347 citations

Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons

1990 • 341 citations

Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus.

1994 • 339 citations

N-methyl-D-aspartate receptor antagonists disrupt the formation of a mammalian neural map.

1992 • 331 citations

Intrathecal MK-801 and local nerve anesthesia synergistically reduce nociceptive behaviors in rats with experimental peripheral mononeuropathy

1992 • 286 citations

Methods for antagonizing glutamate neurotoxicity.

1990 • 277 citations

The primary afferent depolarizing action of kainate in the rat

1986 • 244 citations

Complete penetration of antibodies into vibratome sections after glutaraldehyde fixation and ethanol treatment: light and electron microscopy for neuropeptides.

1992 • 148 citations

Blockade of both NMDA and non-NMDA receptors is required for optimal protection against ischemic neuronal degeneration in the in vivo adult mammalian retina

1991 • 142 citations

Characterization of a Presynaptic Glutamate Receptor

1993 • 132 citations

Regulation of excitatory amino acid release by N-methyl-d-aspartate receptors in rat striatum: in vivo microdialysis studies

1992 • 108 citations

Expression of the mRNA for the rat NMDA receptor (NMDAR1) in the sensory and autonomic ganglion neurons

1992 • 105 citations

Relative involvement of substance P and CGRP mechanisms in antidromic vasodilation in the rat skin

1992 • 79 citations

Glutamate induces a depolarization of adult rat dorsal root ganglion neurons that is mediated predominantly by NMDA receptors

1988 • 74 citations

Characterization of the role of spinal n-methyl-d-aspartate receptors in thermal nociception in the rat

1993 • 67 citations

Synaptic architecture of glomeruli in superficial dorsal horn of rat spinal cord, as shown in serial reconstructions

1985 • 62 citations

Quantitative analysis of substance P and calcitonin gene-related peptide immunohistochemical staining in the dorsal horn of neuropathic MK-801-treated rats

1993 • 60 citations

Localisation of glutamate receptor binding sites and mRNAS to the dorsal horn of the rat spinal cord

1993 • 59 citations

Bidirectional transport of NMDA receptor and ionophore in the vagus nerve

1989 • 29 citations

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