Differential transactivation of the intercellular adhesion molecule 1 gene promoter by Tax1 and Tax2 of human T-cell leukemia viruses

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

1985 • 2,840 citations

Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera.

1981 • 2,281 citations

Adult T-cell leukemia: clinical and hematologic features of 16 cases

1977 • 2,119 citations

Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA.

1983 • 1,555 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

A New Subtype of Human T-Cell Leukemia Virus (HTLV-II) Associated with a T-Cell Variant of Hairy Cell Leukemia

1982 • 1,195 citations

Integration of murine leukemia virus DNA depends on mitosis.

1993 • 931 citations

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus

1994 • 798 citations

Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.

1988 • 741 citations

Chronic progressive myelopathy associated with elevated antibodies to human T‐lymphotropic virus type I and adult T‐cell leukemialike cells

1987 • 634 citations

Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1.

1986 • 519 citations

In vivo cellular tropism of human T-cell leukemia virus type 1

1990 • 425 citations

Regulation of the human interleukin-2 receptor α chain promoter: Activation of a nonfunctional promoter by the transactivator gene of HTLV-I

1987 • 423 citations

Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene.

1985 • 382 citations

Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction.

1989 • 289 citations

A Second Isolate of HTLV-II Associated with Atypical Hairy-Cell Leukemia

1986 • 282 citations

Chronic neurodegenerative disease associated with HTLV-II infection

1992 • 277 citations

The CD2-LFA-3 and LFA-1-ICAM pathways: relevance to T-cell recognition

1989 • 269 citations

Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat

1989 • 239 citations

Pathology of chronic myelopathy associated with HTLV-I infection (HAM/TSP)

1990 • 230 citations

Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia.

1990 • 229 citations

Molecular characterization of genome of a novel human T-cell leukaemia virus

1983 • 196 citations

Identification of factors that interact with the E1A-inducible adenovirus E3 promoter.

1987 • 189 citations

Cloning and characterization of the 5'-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene

1991 • 171 citations

Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB).

1993 • 161 citations

Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia.

1991 • 153 citations

C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells.

1993 • 152 citations

Human T Cell Leukemia Viruses Use a Receptor Determined by Human Chromosome 17

1988 • 144 citations

Isolation of HTLV‐II from a patient with chronic, progressive neurological disease clinically indistinguishable from HTLV‐I‐associated myelopathy/tropical spastic paraparesis

1993 • 133 citations

Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen in HTLV-1-positive T cells

1992 • 127 citations

Status of the transcription factors database (TFD)

1993 • 125 citations

Pleiotropic effect of the human T-cell leukemia virus Tax protein on the DNA binding activity of eukaryotic transcription factors.

1993 • 121 citations

C33 antigen recognized by monoclonal antibodies inhibitory to human T cell leukemia virus type 1-induced syncytium formation is a member of a new family of transmembrane proteins including CD9, CD37, CD53, and CD63.

1992 • 117 citations

In vivo cellular tropism of human T cell leukemia virus type II (HTLV-II).

1992 • 112 citations

The Immunoglobulin Octanucleotide: Independent Activity and Selective Interaction with Enhancers

1987 • 97 citations

Detection of human T lymphotrophic virus type I (HTLV-I) proviral DNA and analysis of T cell receptor V beta CDR3 sequences in spinal cord lesions of HTLV-I-associated myelopathy/tropical spastic paraparesis.

1994 • 93 citations

T-cell activation by autologous human T-cell leukemia virus type I-infected T-cell clones.

1992 • 91 citations

Identification of two distinct elements in the long terminal repeat of HTLV-I responsible for maximum gene expression.

1987 • 91 citations

Activation of the GM-CSF promoter by HTLV-I and -II tax proteins.

1989 • 91 citations

Human T cell leukemia/lymphoma virus, type II (HTLV-II): emergence of an important newly recognized pathogen

1994 • 86 citations

Strong induction of ICAM‐1 in human T cells transformed by human T‐cell‐leukemia virus type 1 and depression of ICAM‐1 or LFA‐1 in adult T‐cell‐leukemia‐derived cell lines

1992 • 76 citations

Induction of ICAM‐1 and LFA‐3 by Tax1 of human T‐cell leukemia virus type 1 and mechanism of down‐regulation of ICAM‐1 or LFA‐1 in adult‐T‐cell‐leukemia cell lines

1995 • 69 citations

Constitutive expression of various chemokine genes in human T-cell lines infected with human T-cell leukemia virus type 1: Role of the viral transactivator Tax

1996 • 66 citations

Infiltration of helper/inducer T lymphocytes heralds central nervous system damage in human T-cell leukemia virus infection.

1992 • 60 citations

E-selectin and vascular cell adhesion molecule-1 mediate adult T-cell leukemia cell adhesion to endothelial cells

1993 • 59 citations

Cell-type-specific transactivation of the parathyroid hormone-related protein gene promoter by the human T-cell leukemia virus type I (HTLV- I) tax and HTLV-II tax proteins

1993 • 53 citations

Efficient transformation of previously activated and dividing T lymphocytes by human T cell leukemia-lymphoma virus

1984 • 51 citations

Tax proteins of human T-cell leukemia virus type 1 and 2 induce expression of the gene encoding erythroid-potentiating activity (tissue inhibitor of metalloproteinases-1, TIMP-1).

1994 • 50 citations

Expression of the HTLV-1 genome and its association with a unique T-cell malignancy

1987 • 50 citations

Human Retroviruses: HTLV-I and HTLV-II

1993 • 49 citations

The human T-cell leukemia virus (HTLV) transactivator (tax) protein

1992 • 49 citations

HTLV-1 p27rex stabilizes human interleukin-2 receptor alpha chain mRNA.

1990 • 47 citations

The mitogenic activity of human T-cell leukemia virus type I is T-cell associated and requires the CD2/LFA-3 activation pathway

1993 • 43 citations

Molecular Interactions between HTLV-1 Tax Protein and the NF-κB/IκB Transcription Complex

1995 • 39 citations

Comparison of the trans-activation capabilities of the human T-cell leukemia virus type I and II chi proteins.

1986 • 36 citations

HTLV-I and HTLV-II tax trans-activate the human EGR-1 promoter through different cis-acting sequences.

1992 • 33 citations

Calcium-dependent homotypic adhesion through leukocyte function- associated antigen-1/intracellular adhesion molecule-1 induces interleukin-1 and parathyroid hormone-related protein production on adult T-cell leukemia cells in vitro

1995 • 30 citations

Transcriptional regulation in the human retrovirus HTLV-1

1993 • 23 citations

Enhanced expression of LFA‐3 on human T‐cell lines and leukemic cells carrying human T‐cell‐leukemia virus type 1

1993 • 23 citations

Regional Localization of the Putative Cell Surface Receptor for HTLV-I to Human Chromosome 17q23.2-17q25.3

1995 • 22 citations

Infection with human T-lymphotropic virus types I and II results in alterations of cellular receptors, including the up-modulation of T-cell counterreceptors CD40, CD54, and CD80 (B7-1)

1995 • 18 citations

Cell Line-dependent Response of the Enhancer element of Simian Virus 40 to Transactivator p40tax Encoded by Human T-cell Leukemia Virus type I

1989 • 14 citations

Human T-cell leukemia virus type I tax induces intracellular adhesion molecule-1 expression in T cells [letter]

1994 • 14 citations

Comparison of the trans-Activation Capabilities of the Human T-Cell Leukemia Virus Type I and II χ Proteins

1986 • 12 citations

Elevated levels of cICAM-1 in patients with human T-cell leukemia virus type I associated myelopathy and adult T-cell leukemia [letter]

1992 • 10 citations

Modulation of HTLV-II-Associated Spontaneous Lymphocyte Proliferation by β2 Integrin CD11a/CD18 Involves Interaction with Its Cognate Ligand, CD54

1994 • 8 citations