Rapid degradation of the heavy chain of class I major histocompatibility complex antigens in the endoplasmic reticulum of human cytomegalovirus-infected cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Protein Oligomerization in the Endoplasmic Reticulum

1989 • 993 citations

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

1981 • 736 citations

Cytotoxic T cells recognize fragments of the influenza nucleoprotein

1985 • 669 citations

Protein degradation in the endoplasmic reticulum

1990 • 659 citations

Cytotoxic T Cells in Cytomegalovirus Infection

1982 • 610 citations

Retardation of fading and enhancement of intensity of immunofluorescence by p-phenylenediamine.

1983 • 544 citations

Assembly of MHC class I molecules analyzed in vitro

1990 • 491 citations

Degradation from the endoplasmic reticulum: Disposing of newly synthesized proteins

1988 • 488 citations

Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens

1988 • 470 citations

CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity

1987 • 432 citations

Interstitial murine cytomegalovirus pneumonia after irradiation: characterization of cells that limit viral replication during established infection of the lungs

1985 • 417 citations

An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens

1985 • 405 citations

Use of endo- and exoglycosidases for structural studies of glycoconjugates

1979 • 398 citations

Primary structure of human transferrin receptor deduced from the mRNA sequence

1984 • 351 citations

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

1988 • 351 citations

[59] Inhibitors of lysosomal function

1983 • 331 citations

Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance

1985 • 322 citations

Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2m gene expression.

1991 • 304 citations

Assembly and maturation of HLA-A and HLA-B antigens in vivo

1979 • 278 citations

Structural features of the cell surface receptor for transferrin that is recognized by the monoclonal antibody OKT9.

1982 • 275 citations

Leupeptin, a Protease Inhibitor, Decreases Protein Degradation in Normal and Diseased Muscles

1978 • 267 citations

Subcellular compartmentalization of saccharide moieties in cultured normal and malignant cells.

1980 • 260 citations

Biosynthesis of HLA-A and HLA-B antigens in vivo.

1980 • 253 citations

Temperature-sensitive steps in the transport of secretory proteins through the Golgi complex in exocrine pancreatic cells.

1986 • 251 citations

A complex between the MHC class I homologue encoded by human cytomegalovirus and β2 microglobulin

1990 • 246 citations

Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly.

1989 • 228 citations

Inhibitors of oligosaccharide processing

1985 • 218 citations

Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins.

1986 • 212 citations

A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum

1987 • 202 citations

Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins.

1987 • 197 citations

pH-dependent function, purification, and intracellular location of a major collagen-binding glycoprotein.

1987 • 180 citations

Antigen Presentation Requires Transport of MHC Class I Molecules from the Endoplasmic Reticulum

1990 • 167 citations

Role of beta2-microglobulin in the intracellular transport and surface expression of murine class I histocompatibility molecules

1989 • 153 citations

Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment.

1988 • 139 citations

Modulation of MHC antigen expression by viruses and oncogenes

1991 • 128 citations

Processing of the gp55-116 envelope glycoprotein complex (gB) of human cytomegalovirus

1989 • 119 citations

Down-regulation of the class I HLA heterodimer and beta2-microglobulin on the surface of cells infected with cytomegalovirus

1992 • 111 citations

Effect of microtubular or translational inhibitors on general cell protein degradation. Evidence for a dual catabolic pathway

1977 • 110 citations

Role of .beta.2-microglobulin in the intracellular processing of HLA antigens

1981 • 109 citations

Inhibition of N-linked oligosaccharide trimming does not interfere with surface expression of certain integral membrane proteins.

1984 • 106 citations

HLA-restricted cytotoxic T lymphocyte and nonthymic cytotoxic lymphocyte responses to cytomegalovirus infection of bone marrow transplant recipients.

1981 • 103 citations

DIRECT INDUCTION OF MHC CLASS I, BUT NOT CLASS II, EXPRESSION ON ENDOTHELIAL CELLS BY CYTOMEGALOVIRUS INFECTION

1989 • 102 citations

Importance of cytotoxic lymphocytes during cytomegalovirus infection in renal transplant recipients

1984 • 84 citations

Construction and characterization of a human cytomegalovirus mutant with the UL18 (class I homolog) gene deleted

1992 • 81 citations

CYTOMEGALOVIRUS-INDUCED REGULATION OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I ANTIGEN EXPRESSION IN HUMAN AORTIC SMOOTH MUSCLE CELLS

1991 • 73 citations

Down-regulation of the Surface Expression of Class I MHC Antigens by Human Cytomegalovirus

1993 • 72 citations

Enhancement of class I HLA antigen expression by cytomegalovirus: Role in amplification of virus infection

1988 • 71 citations

Degradation of unassembled α- and β-spectrin by distinct intracellular pathways: Regulation of spectrin topogenesis by β-spectrin degradation

1985 • 70 citations

Association and dissociation of the murine T cell receptor associated protein (TRAP). Early events in the biosynthesis of a multisubunit receptor.

1988 • 49 citations

Isolation and expression of a cDNA clone encoding HLA-Cw6: unique characteristics of HLA-C encoded gene products

1989 • 41 citations

Enhanced capacity of DNA repair in human cytomegalovirus-infected cells

1981 • 12 citations

The ubiquitin-mediated proteolytic pathway: enzymology and mechanisms of recognition of the proteolytic substrates.

1990 • 10 citations