Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter.

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

1997 • 889 citations

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

1996 • 827 citations

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

1994 • 777 citations

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

1994 • 685 citations

cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats

1996 • 641 citations

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

1994 • 635 citations

Cellular accumulation of the anticancer agent cisplatin: A review

1993 • 557 citations

Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.

1993 • 517 citations

Prediction of Transmembrane Segments in Proteins Utilising Multiple Sequence Alignments

1994 • 466 citations

Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome

1996 • 372 citations

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database

1996 • 338 citations

Coordinated Induction of / Pump and γ-Glutamylcysteine Synthetase by Heavy Metals in Human Leukemia Cells

1996 • 264 citations

Transport of glutathione conjugates and glucuronides by the multidrug resistance proteins MRP1 and MRP2.

1997 • 260 citations

Membrane Topology of a Cysteine-less Mutant of Human P-glycoprotein

1995 • 252 citations

A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells.

1997 • 249 citations

Cadmium tolerance mediated by the yeast AP-1 protein requires the presence of an ATP-binding cassette transporter-encoding gene, YCF1.

1994 • 214 citations

Membrane Topology and Glycosylation of the Human Multidrug Resistance-associated Protein

1996 • 209 citations

Expression of multidrug resistance-associated protein in NIH/3T3 cells confers multidrug resistance associated with increased drug efflux and altered intracellular drug distribution.

1995 • 208 citations

Preliminary definition of a “critical region” of chromosome 13 in q32: Report of 14 cases with 13q deletions and review of the literature

1993 • 159 citations

Characterization of genomic alterations associated with glioma progression by comparative genomic hybridization.

1996 • 159 citations

Development of a highly efficient expression cDNA cloning system: application to oncogene isolation.

1991 • 145 citations

Expression complementary DNA library transfer establishes mrp as a multidrug resistance gene.

1994 • 124 citations

Cross-resistance to methotrexate and metals in human cisplatin-resistant cell lines results from a pleiotropic defect in accumulation of these compounds associated with reduced plasma membrane binding proteins.

1998 • 102 citations

Reduced drug accumulation and multidrug resistance in human breast cancer cells without associated P-glycoprotein or MRP overexpression

1997 • 102 citations

Expression Pattern of MRP in Human Tissues and Adult Solid Tumor Cell Lines

1995 • 93 citations

The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line

1996 • 64 citations

Cross-resistance between cisplatin, antimony potassium tartrate, and arsenite in human tumor cells.

1995 • 51 citations

Mutational analysis of the Saccharomyces cerevisiae ATP‐binding cassette transporter protein Ycf1p

1997 • 51 citations

Chromosomal localization of a gene, GFI1 encoding a novel zinc finger protein reveals a new syntenic region between man and rodents

1995 • 49 citations

Adenosine Triphosphate-Dependent Transport of Leukotriene C4 by Membrane Vesicles Prepared From Cisplatin-Resistant Human Epidermoid Carcinoma Tumor Cells

1994 • 44 citations

Cross-resistance between cisplatin and antimony in a human ovarian carcinoma cell line.

1994 • 32 citations