Lack of effect of grapefruit juice on the pharmacokinetics and pharmacodynamics of amlodipine

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P‐glycoprotein: Implications for drug delivery and activity in cancer chemotherapy

1995 • 856 citations

Grapefruit juice–drug interactions

1998 • 740 citations

Drug Interactions with Grapefruit Juice

1997 • 343 citations

Oxidation of dihydropyridine calcium channel blockers and analogs by human liver cytochrome P-450 IIIA4

1991 • 262 citations

Clinical Pharmacokinetics of Amlodipine

1992 • 229 citations

The pharmacokinetics of amlodipine in healthy volunteers after single intravenous and oral doses and after 14 repeated oral doses given once daily.

1986 • 222 citations

6 ́,7 ́-Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein

1999 • 220 citations

The influence of verapamil on serum digoxin concentration.

1982 • 207 citations

Digoxin-verapamil interaction

1981 • 177 citations

The Metabolism and Pharmacokinetics of Amlodipine in Humans and Animals

1988 • 159 citations

The pharmacokinetic profile of amlodipine

1989 • 148 citations

Relationship between time of intake of grapefruit juice and its effect on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects

1995 • 138 citations

Relationship between time after intake of grapefruit juice and the effect on pharmacokinetics and pharmacodynamics of nisoldipine in healthy subjects

2000 • 129 citations

Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans

1991 • 123 citations

Grapefruit juice-felodipine interaction: reproducibility and characterization with the extended release drug formulation.

1995 • 105 citations

Effect of grapefruit juice on the pharmacokinetics of amlodipine in healthy volunteers

1996 • 98 citations

Analysis of amlodipine in human plasma by gas chromatography

1987 • 87 citations

Repeated consumption of grapefruit juice considerably increases plasma concentrations of cisapride

1999 • 75 citations

Stereoselective pharmacokinetics of dihydropyridine calcium antagonists

1995 • 56 citations

The effect of grapefruit juice on the time-dependent decline of artemether plasma levels in healthy subjects*1

1999 • 56 citations

Determination of (+)- and (−)-Nilvadipine in Human Plasma Using Chiral Stationary-Phase Liquid Chromatography and Gas Chromatography-Mass Spectrometry, and a Preliminary Pharmacokinetic Study in Humans

1987 • 45 citations

Radioligand-binding assay employing P-glycoprotein-overexpressing cells: testing drug affinities to the secretory intestinal multidrug transporter.

1998 • 44 citations

Effects of Amlodipine on Steady-State Digoxin Concentrations and Renal Digoxin Clearance

1988 • 34 citations

Importance of metabolic stability and hepatic distribution to the pharmacokinetic profile of amlodipine

1994 • 21 citations

Neurotransmitters in the Brain

1989 • 20 citations

EFFECT OF GRAPEFRUIT JUICE AND OTHER JUICES ON P-GLYCOPROTEIN FUNCTION OF DRUG ABSORPTION IN THE INTESTINE

1998 • 1 citations

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