Grapefruit juice-felodipine interaction: reproducibility and characterization with the extended release drug formulation.

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

1994 • 2,716 citations

Interaction of citrus juices with felodipine and nifedipine

1991 • 595 citations

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes.

1992 • 536 citations

IMPROVEMENT OF MEDICATION COMPLIANCE IN UNCONTROLLED HYPERTENSION

1976 • 524 citations

Oxidation of dihydropyridine calcium channel blockers and analogs by human liver cytochrome P-450 IIIA4

1991 • 262 citations

Grapefruit juice–felodipine interaction: Mechanism, predictability, and effect of naringin

1993 • 230 citations

Characterization of human cytochrome P450 enzymes

1992 • 227 citations

Effect of grapefruit juice on blood cyclosporin concentration

1995 • 205 citations

Effect of grapefruit juice and naringin on nisoldipine pharmacokinetics

1993 • 191 citations

Grapefruit Juice and Drugs

1994 • 178 citations

Determination of felodipine in plasma by capillary gas chromatography with electron capture detection

1984 • 143 citations

Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans

1991 • 123 citations

Nifedipine-Associated Myocardial Ischemia or Infarction in the Treatment of Hypertensive Urgencies

1987 • 114 citations

Acute effects of drinking grapefruit juice on the pharmacokinetics and dynamics on felodipine ? and its potential clinical relevance

1992 • 110 citations

Trough concentrations of cyclosporine in blood following administration with grapefruit juice

1993 • 105 citations

Quercetin, an in vitro inhibitor of CYP3A, does not contribute to the interaction between nifedipine and grapefruit juice

1993 • 101 citations

A population study of the pharmacokinetics of felodipine.

1991 • 54 citations

Pharmacokinetics of felodipine in patients with liver disease

1989 • 53 citations

Influence of grapefruit juice on the pharmacokinetics of a slow release nifedipine formulation.

1994 • 25 citations

Contribution of the intestine to the first-pass metabolism of felodipine in the rat.

1989 • 19 citations