Prostacyclin (prostaglandin I2, PGI2) inhibits platelet adhesion and thrombus formation on subendothelium

A Platelet-Dependent Serum Factor That Stimulates the Proliferation of Arterial Smooth Muscle Cells In Vitro

1974 • 1,838 citations

HUMAN ARTERIAL AND VENOUS TISSUES GENERATE PROSTACYCLIN (PROSTAGLANDIN X), A POTENT INHIBITOR OF PLATELET AGGREGATION

1977 • 886 citations

The chemical structure of prostaglandin X (prostacyclin)

1976 • 729 citations

Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium

1977 • 683 citations

Modulation of human platelet adenylate cyclase by prostacyclin (PGX)

1977 • 659 citations

Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells.

1977 • 625 citations

Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets

1977 • 601 citations

The effect of salicylates on the hemostatic properties of platelets in man

1968 • 544 citations

DIPYRIDAMOLE AND OTHER PHOSPHODIESTERASE INHIBITORS ACT AS ANTITHROMBOTIC AGENTS BY POTENTIATING ENDOGENOUS PROSTACYCLIN

1978 • 392 citations

Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate--dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome.

1978 • 368 citations

Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium

1974 • 265 citations

Platelet Adhesion, Release and Aggregation in Flowing Blood: Effects of Surface Properties and Platelet Function.

1976 • 264 citations

Cyclic AMP and Platelet Function

1972 • 213 citations

Cultured human skin fibroblasts and arterial cells produce a labile platelet-inhibitory prostaglandin

1977 • 209 citations

Synthesis of prostaglandin I2 (prostacyclin) by human and bovine endothelial cells

1977 • 164 citations

Effect of prostacyclin (PGI2) on platelet adhesion to rabbit arterial subendothelium

1978 • 157 citations

RBC velocity profiles in arterioles and venules of the rabbit omentum

1975 • 120 citations

Platelet interaction with collagen fibrils in flowing blood. II. Impaired adhesion-aggregation in bleeding disorders. A comparison with subendothelium.

1977 • 73 citations

Biochemistry of the Platelet Release Reaction

1975 • 61 citations

Simple efficient synthesis of prostacyclin (PGI2)1

1977 • 54 citations

Interaction of thrombasthenic platelets with subendothelium: Normal adhesion, absent aggregation

1975 • 38 citations

Platelet Adhesion and Platelet Thrombus Formation on Subendothelium of Human Arteries and Veins Exposed to Flowing Blood <i>in vitro</i>. A Comparison with Rabbit Aorta

1979 • 35 citations

Prostaglandin E2: Effects on aggregation, shape change and cyclic AMP of rat platelets

1972 • 34 citations

INTERACTION OF PLATELETS WITH SUBENDOTHELIUM: A NEW METHOD FOR IDENTIFYING AND CLASSIFYING ABNORMALITIES OF PLATELET FUNCTION*

1977 • 28 citations

Polymolecular layers of fibrinogen systems and the genesis of thrombosis

1976 • 24 citations