Effect of prostacyclin (PGI2) on platelet adhesion to rabbit arterial subendothelium

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

1976 • 956 citations

Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis.

1976 • 933 citations

HUMAN ARTERIAL AND VENOUS TISSUES GENERATE PROSTACYCLIN (PROSTAGLANDIN X), A POTENT INHIBITOR OF PLATELET AGGREGATION

1977 • 886 citations

Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium

1977 • 683 citations

Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells.

1977 • 625 citations

The role of blood flow in platelet adhesion, fibrin deposition, and formation of mural thrombi

1973 • 587 citations

Localisation and stimulation of prostacyclin production in vascular cells

1978 • 356 citations

ADHESION OF PLATELETS TO SUBENDOTHELIUM

1972 • 244 citations

Ultrastructural changes of endothelium associated with thrombocytopenia

1975 • 147 citations

Platelet Function

1969 • 138 citations

Eine neue Methode zur Erzeugung von Thromben durch gezielte Überdehnung der Gefäßwand

1963 • 130 citations

The effect of prostacyclin (PGT2) on platelet behaviour. Thrombus formation in vivo and bleeding time.

1979 • 105 citations

Platelet interaction with collagen fibrils in flowing blood. II. Impaired adhesion-aggregation in bleeding disorders. A comparison with subendothelium.

1977 • 73 citations

Platelet Interaction with Collagen Fibrils in Flowing Blood

1977 • 56 citations

Modification of platelet adherence to protein-coated surfaces.

1973 • 38 citations

Ultrastructure and behaviour of platelet thrombi in injured arteries.

1971 • 27 citations

Disappearance of prostacyclin (PGI2) in the circulation of the dog [proceedings].

1978 • 26 citations

Adhesion and aggregation of human platelets to rabbit subendothelium. A new approach for investigation: Specific antibodies

1977 • 15 citations