Fibroblast growth factor

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Anti-Angiogenesis

1972 • 1,167 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

1984 • 937 citations

Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells

1985 • 911 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

The Role of Extracellular Matrix in Development

1985 • 867 citations

Human Endothelial Cells: Use of Heparin in Cloning and Long-Term Serial Cultivation

1983 • 801 citations

Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth

1974 • 786 citations

The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour

1968 • 764 citations

Tumor Growth and Neovascularization: An Experimental Model Using the Rabbit Cornea 2

1974 • 762 citations

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.

1984 • 715 citations

Cultured endothelial cells produce heparinlike inhibitor of smooth muscle cell growth

1981 • 685 citations

The Influence of the Nerve in Regeneration of the Amphibian Extremity

1952 • 620 citations

Purification of a fibroblast growth factor from bovine pituitary.

1975 • 595 citations

Functional role for c-myc in mitogenic response to platelet-derived growth factor

1984 • 578 citations

Trans-filter induction of tubules in mouse metanephrogenic mesenchyme

1956 • 521 citations

Purification of the fibroblast growth factor activity from bovine brain.

1978 • 498 citations

Effect of Oxygen on Developing Retinal Vessels with Particular Reference to the Problem of Retrolental Fibroplasia

1954 • 486 citations

Extracellular matrix.

1981 • 471 citations

Vasculae Reactions of Normal and Malignant Tissues in Vivo. I. Vascular Reactions of Mice to Wounds and to Normal and Neoplastic Transplants

1945 • 466 citations

Development of the Vertebrate Cornea

1980 • 387 citations

Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor

1985 • 372 citations

Factors involved in the modulation of cell proliferation in vivo and in vitro: The role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells

1978 • 360 citations

The identification and partial characterization of the fibroblast growth factor receptor of baby hamster kidney cells.

1985 • 352 citations

Basic and acidic fibroblast growth factors interact with the same cell surface receptors.

1986 • 340 citations

Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies

1985 • 335 citations

An antiproliferative heparan sulfate species produced by postconfluent smooth muscle cells.

1985 • 315 citations

Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin

1978 • 312 citations

Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes

1984 • 303 citations

Purification of two distinct growth factors from bovine neural tissue by heparin affinity chromatography

1984 • 298 citations

Effect of fibroblast growth factor and lipoproteins on the proliferation of endothelial cells derived from bovine adrenal cortex, brain cortex, and corpus luteum capillaries

1986 • 273 citations

The effect of fibroblast growth factor on PC12 cells

1985 • 270 citations

Retina- and eye-derived endothelial cell growth factors: partial molecular characterization and identity with acidic and basic fibroblast growth factors

1985 • 268 citations

Purification and characterization of heparin-binding endothelial cell growth factors.

1986 • 263 citations

The angiogenic activity of the fibroblast and epidermal growth factor

1979 • 261 citations

Corpus Luteum Angiogenic Factor Is Related to Fibroblast Growth Factor*

1985 • 260 citations

The regulation of cell proliferation by calcium and cyclic AMP

1979 • 259 citations

Neurotrophic Relations

1976 • 250 citations

Identification and purification of glial growth factor

1984 • 243 citations

Changes in the distribution of type IV collagen, laminin, proteoglycan, and fibronectin during mouse tooth development

1981 • 243 citations

Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts.

1986 • 241 citations

Epidermal growth factor and thyrotropin-releasing hormone act similarly on a clonal pituitary cell strain. Modulation of hormone production and inhibition of cell proliferation

1980 • 226 citations

Differentiation and vascularization of the metanephric kidney grafted on the chorioallantoic membrane

1983 • 226 citations

Platelet-derived growth factor

1985 • 226 citations

NEUROTROPHIC CONTROL OF LIMB REGENERATION IN THE NEWT*

1974 • 222 citations

Accelerated wound repair, cell proliferation, and collagen accumulation are produced by a cartilage-derived growth factor.

1985 • 221 citations

Effect of heparin on vascular smooth muscle cells. I. Cell metabolism

1985 • 214 citations

Primary structure of bovine brain acidic fibroblast growth factor (FGF)

1985 • 213 citations

The changes in the vascular pattern of the ovary of the albino rat during the estrous cycle

1943 • 212 citations

Degradation of heparan sulfate in the subendothelial extracellular matrix by a readily released heparanase from human neutrophils. Possible role in invasion through basement membranes.

1985 • 210 citations

The growth and morphogenesis of the regenerating forelimb of adult Triturus following denervation at various stages of development

1948 • 210 citations

Heparan sulfates of cultured cells. II. Acid-soluble and -precipitable species of different cell lines

1971 • 208 citations

Control of Bovine Adrenal Cortical Cell Proliferation by Fibroblast Growth Factor. Lack of Effect of Epidermal Growth Factor

1977 • 201 citations

Effect of fibroblast growth factor on the division and fusion of bovine myoblasts.

1976 • 189 citations

Induction of angiogenesis by bovine brain derived class 1 heparin-binding growth factor

1985 • 180 citations

Sulfated proteoglycan synthesis by confluent cultures of rabbit costal chondrocytes grown in the presence of fibroblast growth factor.

1985 • 179 citations

Acidic fibroblast growth factor (FGF) from bovine brain: amino-terminal sequence and comparison with basic FGF.

1985 • 178 citations

A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation.

1985 • 171 citations

Mediators in cell growth and differentiation.

1984 • 166 citations

Mitogenic Growth Factors and Nerve Dependence of Limb Regeneration

1984 • 154 citations

Isolation of Fibroblast Growth Factor from Bovine Adrenal Gland: Physicochemical and Biological Characterization*

1986 • 145 citations

Induction of regeneration of the forelimb of the postmetamorphic frog by augmentation of the nerve supply

1954 • 145 citations

Growth Factors and the Extracellular Matrix

1980 • 142 citations

Epidermal growth factor induces redistribution of actin and α-actinin in human epidermal carcinoma cells

1981 • 139 citations

Bovine retina contains three growth factor activities with different affinity to heparin: eye derived growth factor I, II, III

1985 • 139 citations

Shift in collagen type as an early response to induction of the metanephric mesenchyme.

1981 • 133 citations

Interaction of T lymphocytes and macrophages with cultured vascular endothelial cells: Attachment, invasion, and subsequent degradation of the subendothelial extracellular matrix

1984 • 133 citations

The role of fibroblast growth factor and epidermal growth factor in the proliferative response of the corneal and lens epithelium

1977 • 132 citations

Mitogenic effect of fibroblast growth factor on early passage cultures of human and murine fibroblasts.

1975 • 129 citations

The extracellular matrix and the control of proliferation of vascular endothelial and vascular smooth muscle cells

1980 • 129 citations

Isolation of pituitary fibroblast growth factor by fast protein liquid chromatography (FPLC): Partial chemical and biological characterization

1985 • 128 citations

The mechanism and role of hormone-induced clustering of membrane receptors

1980 • 118 citations

Is There a Ubiquitous Growth Factor in the Eye?

1981 • 111 citations

Effect of a platelet endoglycosidase on cell surface associated heparan sulphate of human cultured endothelial and glial cells

1977 • 108 citations

Vascular endothelial cells maintained in the absence of fibroblast growth factor undergo structural and functional alterations that are incompatible with their in vivo differentiated properties.

1979 • 108 citations

Adult tissues contain chemo-attractants for vascular endothelial cells

1980 • 108 citations

Fibroblast growth factor in the human placenta

1985 • 107 citations

Are factors originating from serum, plasma, or cultured cells involved in the growth‐promoting effect of the extracellular matrix produced by cultured bovine corneal endothelial cells?

1983 • 105 citations

Selective stimulation by mitogens of incorporation of 35S-methionine into a family of proteins released into the medium by 3T3 cells

1980 • 98 citations

Expression of differentiated functions in cancer cells

1982 • 95 citations

Growth factor‐induced proliferation of human fibroblasts in serum‐free culture depends on cell density and extracellular calcium concentration

1984 • 95 citations

A comparison of the responses of cultured myoblasts and chondrocytes to fibroblast and epidermal growth factors

1977 • 95 citations

Presence in brain of a mitogenic agent promoting proliferation of myoblasts in low density culture

1975 • 93 citations

Isolation and partial characterization of an endothelial cell growth factor from the bovine kidney: homology with basic fibroblast growth factor

1985 • 93 citations

Comparison of the ability of basement membranes produced by corneal endothelial and mouse-derived Endodermal PF-HR-9 cells to support the proliferation and differentiation of bovine kidney tubule epithelial cells in vitro.

1984 • 90 citations

Denervation effects on newt limb regeneration: DNA, RNA, and protein synthesis

1969 • 86 citations

Growth and adipose differentiation of sheep preadipocyte fibroblasts in serum‐free medium

1983 • 83 citations

Growth requirements of low‐density rabbit costal chondrocyte cultures maintained in serum‐free medium

1984 • 83 citations

Characterization of Cultured Bovine Adrenocortical Cells and Derived Clonal Lines: Regulation of Steroidogenesis and Culture Life Span*

1979 • 80 citations

Degradation of sulfated proteoglycans in the subendothelial extracellular matrix by human platelet heparitinase.

1984 • 78 citations

The Effects of the Epidermal and Fibroblast Growth Factors on the Replicative Lifespan of Cultured Bovine Granulosa Cells*

1978 • 74 citations

Immunoreactive fibroblast growth factor (FGF) in rat tissues: Molecular weight forms and the effects of hypophysectomy

1985 • 71 citations

The role of fibroblast growth factor and the extracellular matrix in the control of proliferation and differentiation of corneal endothelial cells

1981 • 70 citations

Stimulation of wound healing, using brain extract with fibroblast growth factor (FGF) activity

1982 • 66 citations

An in vitro model to study adipose differentiation in serum-free medium

1982 • 65 citations

Mitogenic effect of a growth factor derived from myelin on denervated regenerates of newt forelimbs

1979 • 63 citations

General endocrinology

1949 • 62 citations

Purification in high yield of brain fibroblast growth factor by preparative isoelectric focusing at pH 9.6.

1982 • 60 citations

Stimulation of wound healing, using brain extract with fibroblast growth factor (PGF) activity

1982 • 60 citations

Direct evidence for transformation of differentiated iris epithelial cells into lens cells

1974 • 60 citations

Synergistic stimulation of S6 ribosomal protein phosphorylation and DNA synthesis by epidermal growth factor and insulin in quiescent 3T3 cells

1982 • 60 citations

Conditioned medium from endothelial cell cultures can restore the normal phenotypic expression of vascular endothelium maintained in vitro in the absence of fibroblast growth factor

1980 • 59 citations

Stimulation of the release of two glycoproteins from mouse 3T3 cells by growth factors and by agents that increase intralysosomal pH

1981 • 57 citations

Structural and functional alterations in the surface of vascular endothelial cells associated with the formation of a confluent cell monolayer and with the withdrawal of fibroblast growth factor

1979 • 56 citations

Superinduction by cycloheximide of mitogen‐induced secreted proteins produced by Balb/c 3T3 cells

1985 • 55 citations

Effect of substrata and fibroblast growth factor on the proliferation in vitro of bovine aortic endothelial cells

1981 • 55 citations

Influence of the pituitary on Wolffian lens regeneration

1973 • 54 citations

Inactivation of a basement membrane component responsible for cell proliferation but not for cell attachment

1982 • 51 citations

Fibroblast Growth Factor Modulates Synthesis of Collagen in Cultured Vascular Endothelial Cells

1982 • 50 citations

Brain-derived fibroblast growth factor: A study of its inactivation

1983 • 50 citations

A human prostatic growth factor (hPGF): Partial purification and characterization

1985 • 49 citations

Stimulation of mitosis in cultured limb blastemata of the newt, Notophthalmus viridescens

1979 • 47 citations

Fibroblast and epidermal growth factors: their uses in vivo and in vitro in studies on cell functions and cell transplantation

1979 • 43 citations

Newt forelimb regeneration blastemas in vitro: Cellular response to explantation and effects of various growth‐promoting substances

1981 • 43 citations

Analysis of histogenesis and regenerative ability of denervated forelimb regenerates of Triturus viridescens

1969 • 37 citations

Stimulation of wound healing, using brain extract with fibroblast growth factor (FGF) activity

1984 • 30 citations

Bovine pituitary Fibroblast Growth Factor has neurotrophic activity on newt limb regenerates and skeletal muscles in vitro

1981 • 26 citations

Utilization of the chick chorioallantoic membrane for in vitro growth of the embryonic murine kidney

1980 • 24 citations