The matrix metalloproteinase pump-1 catalyzes formation of low molecular weight (pro)urokinase in cultures of normal human kidney cells.

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

A novel coumarin‐labelled peptide for sensitive continuous assays of the matrix metalloproteinases

1992 • 692 citations

Proteolytic degradation of extracellular matrix in tumor invasion

1987 • 484 citations

The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases.

1987 • 479 citations

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)

1991 • 454 citations

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes.

1985 • 450 citations

The collagenase gene family in humans consists of at least four members

1988 • 364 citations

Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis

1988 • 354 citations

Directed Plasminogen Activation at the Surface of Normal and Malignant Cells

1991 • 291 citations

Expression and localization of the matrix metalloproteinase pump‐1 (MMP‐7) in human gastric and colon carcinomas

1991 • 288 citations

Expression of metalloproteinase genes in human prostate cancer

1991 • 222 citations

Purification and properties of a small latent matrix metalloproteinase of the rat uterus.

1988 • 220 citations

Pump-1 cDNA codes for a protein with characteristics similar to those of classical collagenase family members

1989 • 212 citations

Expression of collagenase‐related metalloproteinase genes in human lung or head and neck tumours

1991 • 210 citations

Ras oncogene mediated induction of a 92kDa metalloproteinase; strong correlation with the malignant phenotype

1988 • 209 citations

cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases.

1990 • 202 citations

Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line.

1990 • 194 citations

Matrix metalloproteinases. A review.

1990 • 187 citations

An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells

1990 • 177 citations

Purification and characterization of a novel low molecular weight form of single-chain urokinase-type plasminogen activator.

1986 • 114 citations

Stromelysin/transin and tumor progression.

1990 • 104 citations

Urokinase-dependent cell surface proteolysis and cancer.

1990 • 85 citations

The Role of the Matrix Metalloproteinase Stromelysin in the Progression of Squamous Cell Carcinomas

1991 • 72 citations

High level expression of human proteins in murine hybridoma cells: induction by methotrexate in the absence of gene amplification

1991 • 29 citations

Characterization of a metalloprotease which cleaves with high site-specificity the Glu(143)-Leu(144) bond of urokinase

1992 • 18 citations

A-chain isozymes of recombinant and natural urokinases: Preparation, characterization, and their biochemical and fibrinolytic properties

1992 • 8 citations

Reduction of disulfides in urokinase and insertion of a synthetic peptide

1990 • 7 citations