Cells injected with guanosine 5'-[alpha, beta-methylene]triphosphate, an alpha, beta-nonhydrolyzable analog of GTP, show anomalous patterns of tubulin polymerization affecting cell translocation, intracellular movement, and the organization of Golgi elements.

Microtubule Formation in vitro in Solutions Containing Low Calcium Concentrations

1972 • 1,201 citations

Colchicine-binding protein of mammalian brain and its relation to microtubules

1968 • 1,140 citations

Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line.

1982 • 923 citations

A theory of linear and helical aggregations of macromolecules

1962 • 746 citations

Opposite end assembly and disassembly of microtubules at steady state in vitro

1978 • 567 citations

Cytoplasmic microtubules in normal and transformed cells in culture: analysis by tubulin antibody immunofluorescence.

1975 • 307 citations

Implications of treadmilling for the stability and polarity of actin and tubulin polymers in vivo.

1980 • 232 citations

Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth

1977 • 194 citations

The visualization of fluorescent proteins in living cells by video intensification microscopy (VIM)

1978 • 169 citations

Tubulin: Nucleotide binding and enzymic activity

1974 • 152 citations

Immunohistochemical localization of galactosyltransferase in human fibroblasts and HeLa cells.

1981 • 79 citations

Role of nucleotides in tubulin polymerization: effect of guanylyl 5'-methylenediphosphonate.

1977 • 51 citations

Guanasone 5'-(alpha,beta-methylene)triphosphate enhances specifically microtubule nucleation and stops the treadmill of tubulin protomers.

1980 • 44 citations

Effects of Colchicine on the Golgi Complex and Gerl of Cultured Rat Peritoneal Macrophages and Epiphyseal Chondrocytes

1980 • 38 citations

Polymerization of tubulin in the presence of colchicine or podophyllotoxin

1979 • 33 citations