The histidine-binding protein undergoes conformational changes in the absence of ligand as analyzed with conformation-specific monoclonal antibodies.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

ANTIBODY-ANTIGEN COMPLEXES

1990 • 853 citations

BACTERIAL PERIPLASMIC TRANSPORT SYSTEMS: STRUCTURE, MECHANISM, AND EVOLUTION

1986 • 690 citations

Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis

1992 • 482 citations

The 2.3-A resolution structure of the maltose- or maltodextrin-binding protein, a primary receptor of bacterial active transport and chemotaxis.

1991 • 459 citations

The 2.3-A resolution structure of the maltose- or maltodextrin-binding protein, a primary receptor of bacterial active transport and chemotaxis.

1991 • 437 citations

Apolactoferrin structure demonstrates ligand-induced conformational change in transferrins

1990 • 359 citations

Sugar and Signal-Transducer Binding Sites of the Escherichia coli Galactose Chemoreceptor Protein

1988 • 344 citations

Three-dimensional structures of the periplasmic lysine/arginine/ornithine-binding protein with and without a ligand

1993 • 313 citations

Hinge-bending in L-arabinose-binding protein. The “Venus's-flytrap” model.

1982 • 263 citations

Rates of ligand binding to periplasmic proteins involved in bacterial transport and chemotaxis.

1983 • 251 citations

Structural and Functional Aspects of Domain Motions in Proteins

1984 • 246 citations

Periplasmic binding protein structure and function

1989 • 229 citations

Atomic structures of periplasmic binding proteins and the high-affinity active transport systems in bacteria

1990 • 213 citations

The 2 Å resolution structure of the sulfate-binding protein involved in active transport in Salmonella typhimurium

1988 • 200 citations

The Paper Chromatography of Imidazoles

1952 • 190 citations

A single amino acid substitution in a histidine-transport protein drastically alters its mobility in sodium dodecyl sulfate-polyacrylamide gel electrophoresis

1979 • 183 citations

Reconstitution of a bacterial periplasmic permease in proteoliposomes and demonstration of ATP hydrolysis concomitant with transport.

1989 • 164 citations

Two periplasmic transport proteins which interact with a common membrane receptor show extensive homology: complete nucleotide sequences.

1981 • 151 citations

1.7 Å X-ray structure of the periplasmic ribose receptor from Escherichia coli

1992 • 139 citations

The 1.9 A x-ray structure of a closed unliganded form of the periplasmic glucose/galactose receptor from Salmonella typhimurium.

1994 • 123 citations

The membrane-bound proteins of periplasmic permeases form a complex. Identification of the histidine permease HisQMP complex

1991 • 119 citations

Fluorine-19 NMR studies of the D-galactose chemosensory receptor. 1. Sugar binding yields a global structural change

1991 • 105 citations

Structure of the l-arabinose-binding protein from Escherichia coli at 2.4 Å resolution

1981 • 104 citations

The bacterial periplasmic histidine-binding protein. structure/function analysis of the ligand-binding site and comparison with related proteins.

1994 • 97 citations

Structure of the l-leucine-binding protein refined at 2.4 Å resolution and comparison with the Leu/Ile/Val-binding protein structure

1989 • 94 citations

Reconstitution of the Histidine Periplasmic Transport System in Membrane Vesicles

1989 • 91 citations

Crystal structure of the lysine-, arginine-, ornithine-binding protein (LAO) from Salmonella typhimurium at 2.7-A resolution.

1991 • 88 citations

Formaldehyde and photoactivatable cross-linking of the periplasmic binding protein to a membrane component of the histidine transport system of Salmonella typhimurium.

1988 • 86 citations

Purification and Properties of a Component of Histidine Transport in Salmonella typhimurium

1972 • 80 citations

The 1·7 Å Refined X-ray Structure of the Periplasmic Glucose/Galactose Receptor from Salmonella typhimurium

1993 • 80 citations

Investigating protein conformation dynamics and folding with monoclonal antibodies

1991 • 73 citations

Reconstitution of periplasmic transport in inside-out membrane vesicles

1989 • 72 citations

Quantitative assay of the binding of small molecules to protein: Comparison of dialysis and membrane filter assays

1972 • 59 citations

Purification and characterization of the periplasmic lysine-, arginine-, ornithine-binding protein (LAO) from Salmonella typhimurium.

1992 • 56 citations

The mechanism of ligand binding to the periplasmic C4-dicarboxylate binding protein (DctP) from Rhodobacter capsulatus.

1992 • 51 citations

Epitope mapping by mutagenesis distinguishes between the two tertiary structures of the histidine-containing protein HPr.

1991 • 39 citations

Perturbation of the equilibrium between open and closed conformations of the periplasmic C4-dicarboxylate binding protein from Rhodobacter capsulatus

1992 • 31 citations

Use of Monoclonal Antibodies in the Study of the Conformation and Conformational Alterations in Proteins

1988 • 15 citations

Immunochemical analysis of protein conformation

1997 • 7 citations