Characterization of Cytosolic Calcium Oscillations Induced by Phenylephrine and Vasopressin in Single Fura-2-loaded Hepatocytes

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Calcium messenger system: an integrated view.

1984 • 916 citations

Micro-injection of inositol 1,3,4,5-tetrakisphosphate activates sea urchin eggs by a mechanism dependent on external Ca2+

1986 • 775 citations

Cytosolic calcium oscillators

1988 • 690 citations

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1987 • 676 citations

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

1984 • 567 citations

The second messenger linking receptor activation to internal Ca release in liver

1984 • 557 citations

Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones

1983 • 547 citations

Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca2+-dependent K+ channels

1987 • 529 citations

Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver

1985 • 419 citations

Molecular model for receptor-stimulated calcium spiking.

1988 • 416 citations

Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells

1988 • 412 citations

Changes in free cytosolic Ca2+ in hepatocytes following alpha 1-adrenergic stimulation. Studies on Quin-2-loaded hepatocytes.

1983 • 375 citations

Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes.

1984 • 358 citations

Oscillations of cytosolic Ca2+ in pituitary cells due to action potentials

1987 • 331 citations

Vasopressin-, angiotensin II-, and alpha 1-adrenergic-induced inhibition of Ca2+ transport by rat liver plasma membrane vesicles.

1984 • 279 citations

Spatial and temporal aspects of cell signalling

1988 • 278 citations

Agonist-induced oscillations in cytoplasmic free calcium concentration in single rat hepatocytes

1987 • 271 citations

Mechanisms of action of calcium‐mobilizing agonists: some variations on a young theme

1988 • 236 citations

Quantitation and early kinetics of inositol lipid changes induced by vasopressin in isolated and cultured hepatocytes.

1983 • 232 citations

Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate.

1985 • 218 citations

Stimulation of inositol trisphosphate formation in hepatocytes by vasopressin, adrenaline and angiotensin II and its relationship to changes in cytosolic free Ca2+

1985 • 212 citations

Role of anion translocation across the mitochondrial membrane in the regulation of urea synthesis from ammonia by isolated rat hepatocytes.

1975 • 189 citations

Inositol trisphosphate-induced membrane potential oscillations in Xenopus oocytes.

1988 • 160 citations

Cell-specific patterns of oscillating free Ca2+ in carbamylcholine-stimulated insulinoma cells.

1988 • 158 citations

Characterization of oscillations of intracellular calcium concentration in ferret ventricular muscle.

1984 • 134 citations

The role of extracellular Ca2+ in the response of the hepatocyte to Ca2+-dependent hormones.

1985 • 117 citations

Guanine-nucleotide and hormone regulation of polyphosphoinositide phospholipase C activity of rat liver plasma membranes. Bivalent-cation and phospholipid requirements

1987 • 112 citations

Calcium-mobilizing receptors

1987 • 110 citations

The relationships between receptor binding capacity for norepinephrine, angiotensin II, and vasopressin and release of inositol trisphosphate, Ca2+ mobilization, and phosphorylase activation in rat liver.

1985 • 109 citations

Phorbol-ester-induced alterations of free calcium ion transients in single rat hepatocytes

1987 • 108 citations

Spontaneous and chemoattractant-induced oscillations of cytosolic free calcium in single adherent human neutrophils.

1988 • 106 citations

Agonist-stimulated oscillations and cycling of intracellular free calcium in individual cultured muscle cells.

1988 • 105 citations

Novel kinetics of single cell Ca2+ transients in stimulated hepatocytes and A10 cells measured using fura-2 and fluorescent videomicroscopy.

1988 • 93 citations

Imaging asynchronous changes in intracellular Ca2+ in individual stimulated tumor mast cells.

1988 • 92 citations

Gonadotropin-releasing hormone-induced Ca2+ transients in single identified gonadotropes require both intracellular Ca2+ mobilization and Ca2+ influx.

1988 • 90 citations

Regulation of Ca²⁺-Mg²⁺-ATPase Activity in Hepatocyte Plasma Membranes by Vasopressin and Phenylephrine*

1983 • 84 citations

Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillation of intracellular ionized calcium.

1987 • 82 citations

The Croonian Lecture, 1988 - Inositol lipids and calcium signalling

1988 • 81 citations

Calcium oscillations in single adrenal glomerulosa cells stimulated by angiotensin II.

1988 • 73 citations

Spatially resolved cytosolic calcium response to angiotensin II and potassium in rat glomerulosa cells measured by digital imaging techniques.

1987 • 71 citations

How far does phospholipase C activity depend on the cell calcium concentration? A study in intact cells

1987 • 69 citations

Alpha- and beta-adrenergic stimulation of parenchymal cell Ca2+ influx. Influence of extracellular pH.

1984 • 67 citations

Alpha‐adrenergic stimulation of potassium efflux in guinea‐pig hepatocytes may involve calcium influx and calcium release.

1984 • 48 citations

Interactions between insulin and alpha 1-adrenergic agents in the regulation of glycogen metabolism in isolated hepatocytes.

1985 • 46 citations

Sustained oscillations in extracellular calcium concentrations upon hormonal stimulation of perfused rat liver

1987 • 40 citations

Synchronous oscillation of the cytoplasmic Ca2+ concentration and membrane potential in cultured epithelial cells (Intestine 407)

1986 • 36 citations

Evidence that guanosine 5′-[γ-thio]triphosphate stimulates plasma membrane Ca2+ inflow when introduced into hepatocytes

1989 • 12 citations