A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif

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1998 • 8,909 citations

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

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Apoptosis in the Pathogenesis and Treatment of Disease

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Molecular characterization of mitochondrial apoptosis-inducing factor

1999 • 4,031 citations

Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

2000 • 3,415 citations

Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3

1997 • 3,130 citations

IAP family proteins---suppressors of apoptosis

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Caspases: killer proteases

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Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins

2000 • 2,344 citations

The P-loop — a common motif in ATP- and GTP-binding proteins

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DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

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Transforming Growth Factor‐β

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Interdependent SMAD and JNK Signaling in Transforming Growth Factor-β-mediated Transcription

1999 • 534 citations

The domains of death: evolution of the apoptosis machinery

1999 • 406 citations

The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death

1992 • 387 citations

Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures.

1997 • 382 citations

The septin CDCrel-1 binds syntaxin and inhibits exocytosis

1999 • 371 citations

The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins

1994 • 346 citations

Septins: cytoskeletal polymers or signalling GTPases?

1999 • 272 citations

Cell proliferation and apoptosis

1999 • 235 citations

Human IAP-Like Protein Regulates Programmed Cell Death Downstream of Bcl-x_L and Cytochrome c

1998 • 216 citations

Suppression of transforming growth factor-β-induced apoptosis through a phosphatidylinositol 3-kinase/Akt-dependent pathway

1998 • 187 citations

CrmA-inhibitable Cleavage of the 70-kDa Protein Component of the U1 Small Nuclear Ribonucleoprotein during Fas- and Tumor Necrosis Factor-induced Apoptosis

1995 • 179 citations

Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-β in human normal lung epithelial cells

1998 • 164 citations

Induction of Apoptosis by DPC4, a Transcriptional Factor Regulated by Transforming Growth Factor-β through Stress-activated Protein Kinase/c-Jun N-terminal Kinase (SAPK/JNK) Signaling Pathway

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Smad7 mediates apoptosis induced by transforming growth factor β in prostatic carcinoma cells

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Effect of Truncated Forms of the Steroidogenic Acute Regulatory Protein on Intramitochondrial Cholesterol Transfer*

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Regulation of apoptosis induced by transforming growth factor-beta1 in nontumorigenic rat prostatic epithelial cell lines.

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Transforming Growth Factor-β Signaling in Epithelial Cells

1997 • 113 citations

Characterization of the mammalian septin H5: Distinct patterns of cytoskeletal and membrane association from other septin proteins

1999 • 94 citations

Facing death in the fly: genetic analysis of apoptosis in Drosophila

1997 • 82 citations

Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence.

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ICE-like protease (caspase) is involved in transforming growth factor ?1-mediated apoptosis in FaO rat hepatoma cell line

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Finding functions for small nuclear RNAs in yeast

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The Death Inhibitory Molecules CED-9 and CED-4L Use a Common Mechanism to Inhibit the CED-3 Death Protease

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A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11

1997 • 33 citations

Three distinct roles for TGF-beta during intercellular induction of apoptosis: a review.

1999 • 31 citations

Selective loss of the transforming growth factor-beta apoptotic signaling pathway in mutant NRP-154 rat prostatic epithelial cells.

2000 • 28 citations

The effect of furosemide on calcium ion concentration in myocardial cells

1995 • 17 citations