Chapter 11 Proteoglycans and other repulsive molecules in glial boundaries during development and regeneration of the nervous system

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Proteoglycans as modulators of growth factor activities

1991 • 1,338 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Selectins: Interpreters of Cell-Specific Carbohydrate Information During Inflammation

1992 • 1,255 citations

Proteoglycans: many forms and many functions

1992 • 1,183 citations

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

1991 • 1,171 citations

Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

1993 • 1,146 citations

Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes

1991 • 1,088 citations

The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

1993 • 930 citations

Selectins.

1993 • 869 citations

Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro

1990 • 775 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

Principles of neural development

1985 • 627 citations

Axonal guidance during development of the great cerebral commissures: Descriptive and experimental studies, in vivo, on the role of preformed glial pathways

1982 • 572 citations

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

1995 • 566 citations

Sernaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord

1995 • 492 citations

Injury-Induced Proteoglycans Inhibit the Potential for Laminin-Mediated Axon Growth on Astrocytic Scars

1995 • 487 citations

The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth.

1994 • 449 citations

Chondroitin Sulfate as a Regulator of Neuronal Patterning in the Retina

1992 • 415 citations

Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan

1994 • 415 citations

Astrocytes Block Axonal Regeneration in Mammals by Activating the Physiological Stop Pathway

1987 • 400 citations

Molecular and cellular characterization of the glial roof plate of the spinal cord and optic tectum: A possible role for a proteoglycan in the development of an axon barrier

1990 • 387 citations

Inhibition of neurite outgrowth on astroglial scars in vitro

1990 • 374 citations

Fasciclin IV: Sequence, expression, and function during growth cone guidance in the grasshopper embryo

1992 • 369 citations

Isolation of a neural chondroitin sulfate proteoglycan with neurite outgrowth promoting properties.

1994 • 361 citations

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension

1995 • 352 citations

The role of proteoglycans in cell adhesion, migration and proliferation

1992 • 350 citations

Interactions of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type protein tyrosine phosphatase, with neurons, glia, and neural cell adhesion molecules.

1994 • 322 citations

Neuronal cell–cell adhesion depends on interactions of N-CAM with heparin-like molecules

1986 • 270 citations

Nervous tissue proteoglycans

1993 • 269 citations

Functional characterization of chondroitin sulfate proteoglycans of brain: interactions with neurons and neural cell adhesion molecules.

1993 • 268 citations

Nerve fiber growth in culture on fibronectin, collagen, and glycosaminoglycan substrates

1983 • 266 citations

A chondroitin sulfate proteoglycan may influence the direction of retinal ganglion cell outgrowth

1991 • 264 citations

Peanut agglutinin and chondroitin-6-sulfate are molecular markers for tissues that act as barriers to axon advance in the avian embryo

1991 • 260 citations

Function of proteoglycans in the extracellular matrix

1993 • 257 citations

Embryonic development of axon pathways in the Drosophila CNS. I. A glial scaffold appears before the first growth cones

1989 • 256 citations

Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue.

1994 • 255 citations

Formation of an olfactory glomerulus: Morphological aspects of development and organization

1992 • 254 citations

Putative Inhibitory Extracellular Matrix Molecules at the Dorsal Root Entry Zone of the Spinal Cord during Development and after Root and Sciatic Nerve Lesions

1993 • 252 citations

Thalamocortical axons extend along a chondroitin sulfate proteoglycan- enriched pathway coincident with the neocortical subplate and distinct from the efferent path

1994 • 244 citations

Localized collapsing cues can steer growth cones without inducing their full collapse

1995 • 241 citations

GLIOSIS FOLLOWING CNS INJURY: THE ANATOMY OF ASTROCYTIC SCARS AND THEIR INFLUENCES ON AXONAL ELONGATION

1986 • 231 citations

A family of molecules related to collapsin in the embryonic chick nervous system

1995 • 225 citations

Neurite outgrowth on a step gradient of chondroitin sulfate proteoglycan (CS‐PG)

1992 • 219 citations

An inhibitor of neurite outgrowth produced by astrocytes

1994 • 200 citations

Degenerative and regenerative responses of injured neurons in the central nervous system of adult mammals

1991 • 200 citations

Immunocytochemical demonstration of early appearing astroglial structures that form boundaries and pathways along axon tracts in the fetal brain

1993 • 194 citations

Glial Boundaries in the Developing Nervous System

1993 • 188 citations

Intercellular space is affected by the polysialic acid content of NCAM.

1992 • 179 citations

Chondroitin Sulfate Proteoglycans Are Associated with the Lesions of Alzheimer's Disease

1993 • 175 citations

Inhibitory effects of brain chondroitin sulfate proteoglycans on neurite outgrowth from PC12D cells.

1991 • 171 citations

Proteoglycans of basement membranes

1993 • 166 citations

Boundaries and inhibitory molecules in developing neural tissues

1995 • 162 citations

On the importance of being inhibited, or saying no to growth cones

1988 • 158 citations

Inhibitory effects of brain chondroitin sulfate proteoglycans on neurite outgrowth from PC12D cells

1991 • 155 citations

Identification of a developmentally regulated keratan sulfate proteoglycan that inhibits cell adhesion and neurite outgrowth

1991 • 154 citations

Spatial and temporal changes in the distribution of proteoglycans during avian neural crest development

1991 • 148 citations

β-Amyloid of Alzheimer's Disease Induces Reactive Gliosis That Inhibits Axonal Outgrowth

1993 • 148 citations

Binding of two growth factor families to separate domains of the proteoglycan betaglycan.

1992 • 147 citations

In vitro control of neuronal polarity by glycosaminoglycans

1992 • 144 citations

Glial patterns during early development of antennal lobes of Manduca sexta: A comparison between normal lobes and lobes deprived of antennal axons

1987 • 138 citations

Purification, characterization and developmental expression of a brain-specific chondroitin sulfate proteoglycan, 6B4 proteoglycan/phosphacan

1995 • 134 citations

Amphibian neural crest cell migration on purified extracellular matrix components: a chondroitin sulfate proteoglycan inhibits locomotion on fibronectin substrates.

1987 • 132 citations

Boundaries during normal and abnormal brain development: In vivo and in vitro studies of glia and glycoconjugates

1990 • 131 citations

The coordinated regulation of heparan sulfate, syndecans and cell behavior

1993 • 129 citations

Inhibition of neural crest cell migration by aggregating chondroitin sulfate proteoglycans is mediated by their hyaluronan-binding region

1990 • 124 citations

Glycoconjugates mark a transient barrier to neural crest migration in the chicken embryo

1994 • 123 citations

Characterization of a Neurite Outgrowth Inhibitor Expressed After CNS Injury

1993 • 118 citations

Tenascin knockout mice: barrels, boundary molecules, and glial scars

1995 • 118 citations

Lectins demarcate the barrel subfield in the somatosensory cortex of the early postnatal mouse

1986 • 117 citations

A POTENT INHIBITOR OF NEURITE OUTGROWTH THAT PREDOMINATES IN THE EXTRACELLULAR MATRIX OF REACTIVE ASTROCYTES

1996 • 115 citations

Proteoglycans in the nervous system

1993 • 114 citations

Morphogenesis of sclerotome and neural crest in avian embryos

1986 • 110 citations

Involvement of a chondroitin sulfate proteoglycan in the avoidance of chick epidermis by dorsal root ganglia fibers: A study using β-d-xyloside

1991 • 102 citations

Guidance of cerebellofugal axons in the rat embryo: Directed growth toward the floor plate and subsequent elongation along the longitudinal axis

1995 • 100 citations

Isolation and characterization of the glycosaminoglycan component of rabbit thrombomodulin proteoglycan.

1990 • 99 citations

Multiple Factors Govern Intraretinal Axon Guidance: A Time-Lapse Study

1995 • 98 citations

Chemorepulsion of developing motor axons by the floor plate

1995 • 98 citations

Unique Changes of Ganglion Cell Growth Cone Behavior Following Cell Adhesion Molecule Perturbations: A Time-Lapse Study of the Living Retina

1995 • 97 citations

Astrocyte topography and tenascin/cytotactin expression: correlation with the ability to support neuritic outgrowth

1990 • 97 citations

Cell adhesion and proteoglycans: I. the effect of exogenous proteoglycans on the attachment of chick embryo fibroblasts to tissue culture plastic and collagen

1979 • 97 citations

Axon guidance: A compelling case for repelling growth cones

1995 • 95 citations

Monoclonal antibody to glial fibrillary acidic protein reveals a parcellation of individual barrels in the early postnatal mouse somatosensory cortex

1986 • 93 citations

Structural requirements for neural cell adhesion molecule-heparin interaction.

1990 • 93 citations

Axon guidance by diffusible repellants and attractants

1994 • 87 citations

Influence of glycosaminoglycans on neurite morphology and outgrowth patterns in vitro

1989 • 87 citations

Axon pathway boundaries in the developing brain. I. Cellular and molecular determinants that separate the optic and olfactory projections

1987 • 86 citations

Expression of glial fibrillary acidic protein and its relation to tract formation in embryonic zebrafish (Danio rerio)

1995 • 81 citations

Regionally specific properties of midbrain glia: I. Interactions with midbrain neurons

1995 • 78 citations

Sulfated glycosaminoglycans modify growth factor‐induced neurite outgrowth in PC12 cells

1988 • 76 citations

Regrowth of lesioned dorsal root nerve fibers into the spinal cord of neonatal rats

1987 • 75 citations

Tenascin-C expression by neurons and glial cells in the rat spinal cord: Changes during postnatal development and after dorsal root or sciatic nerve injury

1995 • 73 citations

Role of Astroglial Extracellular Matrix in the Formation of Rat Olfactory Bulb Glomeruli

1993 • 73 citations

Glycoconjugate boundaries during early postnatal development of the neostriatal mosaic

1988 • 72 citations

Floor plate chemoattracts crossed axons and chemorepels uncrossed axons in the vertebrate brain

1995 • 71 citations

Differential effects of glycosaminoglycans on neurite outgrowth from hippocampal and thalamic neurones

1994 • 68 citations

Glial cells form boundaries for developing insect olfactory glomeruli

1990 • 68 citations

Exogenous glycosaminoglycans induce complete inversion of retinal ganglion cell bodies and their axons within the retinal neuroepithelium.

1994 • 67 citations

A central nervous system keratan sulfate proteoglycan: localization to boundaries in the neonatal rat brain

1993 • 66 citations

Gliosis and axonal sprouting in the hippocampus of epileptic rats are associated with an increase of tenascin-C immunoreactivity

1995 • 63 citations

Functional interactions of neuronal heparan sulphate proteoglycans with laminin

1990 • 63 citations

Axon-glia interactions regulate ECM patterning in the postnatal rat olfactory bulb

1994 • 62 citations

Regional Differences in Reactive Gliosis Induced by Substrate-Bound β-Amyloid

1994 • 61 citations

Neuronal and Nonneuronal Influences on Retinal Ganglion Cell Survival, Axonal Regrowth, and Connectivity after Axotomy^a

1991 • 59 citations

Heterogeneity among astrocytes in reactive gliosis.

1994 • 55 citations

Characterization of a heparan sulfate proteoglycan that copurifies with the neural cell adhesion molecule

1989 • 55 citations

Reinnervation of the mammalian spinal cord after neonatal dorsal root crush

1988 • 54 citations

Structural Domains in Chondroitin Sulfate Identified by Anti-Chondroitin Sulfate Monoclonal Antibodies. Immunosequencing of Chondroitin Sulfates

1993 • 54 citations

Neurite outgrowth inhibitors associated with glial cells and glial cell lines

1993 • 54 citations

Claustrin, an antiadhesive neural keratan sulfate proteoglycan, is structurally related to MAP1B

1994 • 48 citations

Glia-neuron interactions at the midline of the developing mammalian brain and spinal cord.

1993 • 48 citations

Molecular Correlates of Spinal Cord Repair in the Embryonic Chick: Heparan Sulfate and Chondroitin Sulfate Proteoglycans

1994 • 45 citations

Expression of the barrier-associated proteins EAP-300 and claustrin in the developing central nervous system

1992 • 42 citations

Domains of neuronal heparan sulphate proteoglycans involved in neurite growth on laminin

1991 • 42 citations

Association of laminin with heparan and chondroitin sulfate-bearing proteoglycans in neurite-promoting factor complexes from rat schwannoma cells

1987 • 40 citations

A carbohydrate polymer that effectively prevents epidural fibrosis at laminectomy sites in the rat

1991 • 39 citations

Midline glia of the tectum: a barrier for developing retinal axons.

1993 • 34 citations

Glial environment in the developing superior colliculus of hamsters in relation to the timing of retinal axon ingrowth

1995 • 26 citations

Regenerative neunte growth modulation associated with astrocyte proteoglycans

1993 • 21 citations

Expression of a keratan sulfate proteoglycan during development of the dorsal lateral geniculate nucleus in the ferret

1994 • 21 citations

Novel neurite growth-inhibitory properties of an astrocyte proteoglycan

1993 • 14 citations

Proteoglycans and the modulation of cell adhesion by steric exclusion

1993 • 14 citations

Astrocyte proteoglycans in a model of reactive gliosis.

1994 • 1 citations