Brain proline-directed protein kinase is a neurofilament kinase which displays high sequence homology to p34cdc2.

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

1987 • 1,153 citations

Intermediate Filaments: A Chemically Heterogeneous, Developmentally Regulated Class of Proteins

1982 • 1,021 citations

A family of human cdc2-related protein kinases.

1992 • 928 citations

Cyclin is a component of maturation-promoting factor from Xenopus

1990 • 674 citations

Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

1991 • 493 citations

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

1991 • 475 citations

Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites.

1991 • 439 citations

Identification of the major multiphosphorylation site in mammalian neurofilaments.

1988 • 394 citations

The fission yeast cdc2/cdc13/suc1 protein kinase: Regulation of catalytic activity and nuclear localization

1989 • 392 citations

The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.

1990 • 377 citations

The structure, biochemical properties, and immunogenicity of neurofilament peripheral regions are determined by phosphorylation state.

1985 • 325 citations

The distribution of phosphorylation sites among identified proteolytic fragments of mammalian neurofilaments.

1983 • 291 citations

A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1.

1991 • 265 citations

Purification and characterization of a novel proline-directed protein kinase from bovine brain.

1992 • 238 citations

CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle.

1992 • 230 citations

Cloning by differential screening of a Xenopus cDNA coding for a protein highly homologous to cdc2.

1991 • 225 citations

Phosphorylation of neurofilament H subunit at the tail domain by CDC2 kinase dissociates the association to microtubules.

1991 • 140 citations

Phosphate content of mammalian neurofilaments.

1982 • 135 citations

Posttranslational modification of a neurofilament protein during axoplasmic transport: implications for regional specialization of CNS axons

1982 • 117 citations

Dephosphorylation-induced interactions of neurofilaments with microtubules.

1990 • 88 citations

Proline-directed protein phosphorylation and cell cycle regulation

1991 • 72 citations

Phosphorylation of caldesmon by cdc2 kinase.

1991 • 63 citations

Mutations at sites involved in Suc1 binding inactivate Cdc2.

1991 • 63 citations

Synthesis of p34, the mammalian homolog of the yeast cdc2+/CDC28 protein kinase, is stimulated during adenovirus-induced proliferation of primary baby rat kidney cells.

1988 • 54 citations

Identification of six phosphorylation sites in the COOH-terminal tail region of the rat neurofilament protein M.

1992 • 44 citations

Platelet-activating factor- and thrombin-induced stimulation of p34cdc2-cyclin histone H1 kinase activity in platelets

1991 • 24 citations

cdc2 Protein Kinase: Interactions with Cyclins and sucl

1991 • 7 citations