Mechanism of the Nucleotide Exchange Reaction in Eukaryotic Polypeptide Chain Initiation

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

EUKARYOTIC PROTEIN SYNTHESIS

1985 • 538 citations

Initiation of protein synthesis in mammalian cells

1986 • 359 citations

The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2.

1988 • 325 citations

The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins.

1987 • 190 citations

A GDP/GTP exchange factor essential for eukaryotic initiation factor 2 cycling in Ehrlich ascites tumor cells and its regulation by eukaryotic initiation factor 2 phosphorylation.

1983 • 177 citations

Nucleotide regulation of a eukaryotic protein synthesis initiation complex

1975 • 143 citations

Phosphorylation inhibits guanine nucleotide exchange on eukaryotic initiation factor 2

1982 • 141 citations

Mechanism of polypeptide chain initiation in eukaryotes and its control by phosphorylation of the alpha subunit of initiation factor 2.

1982 • 134 citations

Binding and release of eukaryotic initiation factor eIF-2 and GTP during protein synthesis initiation.

1978 • 107 citations

Phosphorylation of the guanine nucleotide exchange factor from rabbit reticulocytes regulates its activity in polypeptide chain initiation.

1988 • 98 citations

Interactions between the elongation factors: The displacement of GDP from the Tu-GDP complex by factor Ts

1970 • 91 citations

The association of NADPH with the guanine nucleotide exchange factor from rabbit reticulocytes: a role of pyridine dinucleotides in eukaryotic polypeptide chain initiation.

1986 • 72 citations

Regulation of protein synthesis in eukaryotes. Mode of action of eRF, an eIF-2-recycling factor from rabbit reticulocytes involved in GDP/GTP exchange

1984 • 64 citations

Kinetics of Chemical and Enzyme-Catalyzed Reactions

1977 • 62 citations

Studies on the role of eukaryotic nucleotide exchange factor in polypeptide chain initiation.

1984 • 57 citations

Intrinsic fluorescence of elongation factor Tu in its complexes with GDP and elongation factor Ts

1987 • 40 citations

Evidence for simultaneous derepression of messenger RNA and the guanine nucleotide exchange factor in fertilized sea urchin eggs

1987 • 37 citations

Protein synthesis in brine shrimp embryos and rabbit reticulocytes. The effect of Mg2+ on binary (eukaryotic initiation factor 2 X GDP) and ternary (eukaryotic initiation factor 2 X GTP X met-tRNAf) complex formation.

1983 • 37 citations

Molecular Aspects of Development in the Brine Shrimp Artemia

1984 • 28 citations

Structural studies on the eukaryotic chain initiation factor 2 from rabbit reticulocytes and brine shrimp Artemia embryos. Phosphorylation by the heme-controlled repressor and casein kinase II.

1986 • 26 citations

The isolation and characterization from rabbit reticulocytes of two forms of eukaryotic initiation factor 2 having different beta-polypeptides.

1987 • 21 citations

Interaction of a fluorescent analog of GDP with elongation factor Tu: steady-state and time-resolved fluorescence studies

1987 • 18 citations

Evaluation and significance of kinetic parameters governing function of protein synthesis initiation factors eIF‐2 and eIF‐2B

1985 • 14 citations

Interaction of Subunits of Polypeptide Chain Elongation Factor 1 from Pig Liver

1978 • 13 citations

Polish university compromise

1982 • 7 citations