Regulation of protein synthesis in eukaryotes. Mode of action of eRF, an eIF-2-recycling factor from rabbit reticulocytes involved in GDP/GTP exchange

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Processing of Adenovirus 2-Induced Proteins

1973 • 762 citations

Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

1977 • 750 citations

The mechanism of action of protein synthesis initiation factors from rabbit reticulocytes.

1978 • 436 citations

New initiation factor activity required for globin mRNA translation.

1983 • 416 citations

Structure and function of mammalian ribosomes

1970 • 380 citations

Initiation of protein synthesis II a convenient assay for the ribosome-dependent synthesis of N-formyl-C14-methionylpuromycin

1966 • 353 citations

Initiation of mammalian protein synthesis

1977 • 337 citations

The Regulation of Initiation of Mammalian Protein Synthesis

1981 • 266 citations

Control of globin synthesis: The role of heme

1972 • 257 citations

Regulation of protein synthesis initiation in eucaryotes

1983 • 227 citations

Regulation of protein synthesis in reticulocyte lysates: phosphorylation of methionyl-tRNAf binding factor by protein kinase activity of translational inhibitor isolated from hemedeficient lysates.

1976 • 221 citations

Purification of the eukaryotic initiation factor 2-eukaryotic initiation factor 2B complex and characterization of its guanine nucleotide exchange activity during protein synthesis initiation.

1983 • 203 citations

Specificity of the protein kinase activity associated with the hemin-controlled repressor of rabbit reticulocyte.

1976 • 200 citations

Stimulation of globin-chain initiation by hemin in the reticulocyte cell-free system.

1968 • 184 citations

A GDP/GTP exchange factor essential for eukaryotic initiation factor 2 cycling in Ehrlich ascites tumor cells and its regulation by eukaryotic initiation factor 2 phosphorylation.

1983 • 177 citations

Purification of a factor that restores translation of vesicular stomatitis virus mRNA in extracts from poliovirus-infected HeLa cells.

1980 • 164 citations

Phosphorylation inhibits guanine nucleotide exchange on eukaryotic initiation factor 2

1982 • 141 citations

Hemin control of globin synthesis: An assay for the inhibitor formed in the absence of hemin and some characteristics of its formation

1971 • 138 citations

Mechanism of polypeptide chain initiation in eukaryotes and its control by phosphorylation of the alpha subunit of initiation factor 2.

1982 • 134 citations

Additional evidence that the hemin-controlled translational repressor from rabbit reticulocytes is a protein kinase

1977 • 122 citations

Regulation of protein synthesis in rabbit reticulocyte lysates: purification and initial characterization of the cyclic 3':5'-AMP independent protein kinase of the heme-regulated translational inhibitor.

1976 • 121 citations

Effect of phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 on the function of reversing factor in the initiation of protein synthesis.

1983 • 120 citations

Studies on the role of factor Ts in polypeptide synthesis

1970 • 116 citations

Control of Globin Synthesis in Cell-Free Preparations of Reticulocytes by Formation of a Translational Repressor That is Inactivated by Hemin

1972 • 112 citations

Binding and release of eukaryotic initiation factor eIF-2 and GTP during protein synthesis initiation.

1978 • 107 citations

Purification and Characterization of a Protein Factor that Reverses the Inhibition of Protein Synthesis by the Heme‐Regulated Translational Inhibitor in Rabbit Reticulocyte Lysates

1979 • 107 citations

Binding and release of radiolabeled eukaryotic initiation factors 2 and 3 during 80 S initiation complex formation

1979 • 106 citations

Mechanism of translational control by partial phosphorylation of the alpha subunit of eukaryotic initiation factor 2.

1984 • 94 citations

[3] Protein synthesis initiation factors from rabbit raticulocytes: Purification, characterization, and radiochemical labeling

1979 • 92 citations

Regulation of protein synthesis in rabbit reticulocyte lysates by the heme-regulated protein kinase: Inhibition of interaction of Met-tRNA _f ^Met binding factor with another initiation factor in formation of Met-tRNA _f ^Met ·40S ribosomal subunit complexes

1978 • 80 citations

Characteristics of eukaryotic initiation factor 2 and its subunits.

1980 • 71 citations

Role of 3':5'-cyclic-AMP-dependent protein kinase in regulation of protein synthesis in reticulocyte lysates.

1977 • 70 citations

A Comparison of the Initiation Factors of Eukaryotic Protein Synthesis from Ribosomes and from the Postribosomal Supernatant

1979 • 68 citations

Mode of action of the heme-controlled translational inhibitor: relationship of eukaryotic initiation factor 2-stimulating protein to translation restoring factor.

1981 • 67 citations

The Mechanism of Action of Eukaryotic Initiation Factor 4C in Protein Synthesis

1980 • 66 citations

[44] Specific aminoacylation of the methionine-apecific tRNA's of eukaryotes

1974 • 64 citations

Initiation of eukaryotic protein synthesis

1981 • 60 citations

Control of protein synthesis by hemin. Isolation and characterization of a supernatant factor from rabbit reticulocyte lysate

1976 • 50 citations

Regulation of protein synthesis in rabbit reticulocyte lysates: characteristics of inhibition of protein synthesis by a translational inhibitor from heme-deficient lysates and its relationship to the initiation factor which binds Met-tRNAf.

1976 • 48 citations

Assembly and breakdown of mammalian protein synthesis initiation complexes: regulation by guanine nucleotides and by phosphorylation of initiation factor eIF-2

1983 • 47 citations

Regulation of Protein Synthesis in Rabbit Reticulocyte Lysates. Phosphorylation of eIF-2 Does Not Inhibit Its Capacity to Recycle

1980 • 41 citations

Indirect inactivation of eukaryotic initiation factor 2 in reticulocyte lysate by selenite.

1980 • 32 citations

Functional Relationships between a Reticulocyte Polypeptide‐Chain‐Initiation Factor (IF‐MP) and the Translational Inhibitor Involved in Regulation of Protein Synthesis by Haemin

1976 • 31 citations

Protein synthesis in rabbit reticulocytes: characteristics of a ribosomal factor that reverses inhibition of protein synthesis in heme-deficient lysates.

1978 • 29 citations

[10] Isolation and purification of initiation factors of protein synthesis from rabbit reticulocyte lysate

1979 • 29 citations

Mode of action of protein synthesis initiation factor eIF‐1 from rabbit reticulocytes

1980 • 29 citations

[43] Fractionation of rabbit liver methionyl-tRNA species

1974 • 27 citations

Purification and partial characterization of the catalytic subunit of cAMP-dependent protein kinases from reticulocytes

1979 • 23 citations

The Control of the Rate of Initiation of Eukaryotic Protein Synthesis

1983 • 18 citations