Immunohistochemistry of cholinergic receptors

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat

1989 • 1,049 citations

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin

1985 • 1,037 citations

Autoimmune Response to Acetylcholine Receptor

1973 • 1,019 citations

CHOLINERGIC AND NON‐CHOLINERGIC NERVE ENDINGS IN RAT BRAIN–I

1962 • 784 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

Immunochemistry on ultrathin frozen sections

1980 • 755 citations

Organization and morphological characteristics of cholonergic neurons: an immunocytochemical study with a monoclonal antibody to choline acetyltransferase

1983 • 745 citations

Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.

1989 • 627 citations

THE ACTION OF CERTAIN ESTERS AND ETHERS OF CHOLINE, AND THEIR RELATION TO MUSCARINE

1914 • 604 citations

On the reaction of cells and of nerve‐endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari

1905 • 581 citations

Use of a Snake Venom Toxin to Characterize the Cholinergic Receptor Protein

1970 • 575 citations

Cholinergic and noradrenergic modulation of thalamocortical processing

1989 • 488 citations

Nicotinic acetylcholine binding sites in Alzheimer's disease

1986 • 485 citations

Release of acetylcholine at voluntary motor nerve endings

1936 • 480 citations

Localization of a family of muscarinic receptor mRNAs in rat brain

1988 • 472 citations

Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits.

1980 • 452 citations

ISOLATION OF SYNAPTIC VESICLES AND STRUCTURAL ORGANIZATION OF THE ACETYLCHOLINE SYSTEM WITHIN BRAIN NERVE ENDINGS*

1963 • 435 citations

Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family.

1987 • 431 citations

Mapping of surface structures of electrophorus acetylcholine receptor using monoclonal antibodies.

1981 • 412 citations

Immunocytochemical localization of choline acetyltransferase in rat cerebral cortex: A study of cholinergic neurons and synapses

1985 • 390 citations

Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system

1987 • 350 citations

An anatomical study of cholinergic innervation in rat cerebral cortex

1988 • 345 citations

Direct autoradiographic determination of M1 and M2 muscarinic acetylcholine receptor distribution in the rat brain: Relation to cholinergic nuclei and projections

1986 • 326 citations

Functional Expression of a New Pharmacological Subtype of Brain Nicotinic Acetylcholine Receptor

1988 • 314 citations

A unique regulatory profile and regional distribution of [3H]pirenzepine binding in the rat provide evidence for distinct M1 and M2 muscarinic receptor subtypes

1983 • 298 citations

The chemical transmitter at synapses in a sympathetic ganglion

1934 • 279 citations

Über humorale Übertragbarkeit der Herznervenwirkung

1926 • 253 citations

An atlas of the regional and laminar distribution of choline acetyltransferase immunoreactivity in rat cerebral cortex

1989 • 237 citations

A new myasthenic syndrome with end‐plate acetylcholinesterase deficiency, small nerve terminals, and reduced acetylcholine release

1977 • 236 citations

Pirenzepine distinguishes between muscarinic receptor-mediated phosphoinositide breakdown and inhibition of adenylate cyclase.

1985 • 217 citations

Quantitative light microscopic autoradiographic localization of cholinergic muscarinic receptors in the human brain: Forebrain

1987 • 215 citations

alpha-Bungarotoxin binding and cholinergic receptor function on a rat sympathetic nerve line

1977 • 210 citations

Acetylcholine hyperpolarizes central neurones by acting on an M2 muscarinic receptor

1986 • 196 citations

The effects of nicotine on brain neurotransmitter systems

1982 • 191 citations

Reductions in [ ³ H]nicotinic acetylcholine binding in Alzheimer's disease and Parkinson's disease

1988 • 186 citations

Nicotinic Stimulation of [³H]Acetylcholine Release from Mouse Cerebral Cortical Synaptosomes

1984 • 183 citations

Diversity of structure, signaling and regulation within the family of muscarinic cholinergic receptors

1992 • 179 citations

Muscarinic cholinergic receptors: Autoradiographic localization of high and low affinity agonist binding sites

1980 • 172 citations

Choline ester formation in, and choline esterase activities of, tissues in vitro

1936 • 166 citations

An improved procedure for immunoelectron microscopy: ultrathin plastic embedding of immunolabeled ultrathin frozen sections.

1984 • 158 citations

Neurotransmitter Receptor Mapping by Autoradiography and Other Methods

1986 • 150 citations

Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease

1991 • 149 citations

Muscarinic antagonist binding site heterogeneity as evidenced by autoradiography after direct labeling with [3H]-QNB and [3H]-pirenzepine

1984 • 148 citations

Structurally different neuronal nicotinic acetylcholine receptor subtypes purified and characterized using monoclonal antibodies

1987 • 137 citations

Cholinergic mechanisms in the rat somatosensory cerebral cortex

1972 • 136 citations

Muscarinic and dopaminergic receptors in the aging human brain

1987 • 130 citations

Pharmacological properties of immuno-isolated neuronal nicotinic receptors

1986 • 127 citations

Über humorale übertragbarkeit der Herznervenwirkung

1924 • 122 citations

Actions of snake venom toxins on neuronal nicotinic receptors and other neuronal receptors

1985 • 117 citations

Organization of ligand binding sites at the acetylcholine receptor: a study with monoclonal antibodies

1983 • 116 citations

The separation of synaptic vesicles from disrupted nerve-ending particles

1963 • 115 citations

The cholinergic nature of the nerves to the electric organ of the Torpedo (Torpedo marmorata)

1942 • 113 citations

Evolution of neurotransmitter receptor systems

1988 • 108 citations

Surface and intracellular distribution of a putative neuronal nicotinic acetylcholine receptor.

1986 • 107 citations

Effects of Postmortem Delay and Temperature on Neurotransmitter Receptor Binding in a Rat Model of the Human Autopsy Process

1984 • 105 citations

Immunohistochemical localization of a neuronal nicotinic acetylcholine receptor in mammalian brain.

1987 • 99 citations

Influence of chronic neostigmine treatment on the number of acetylcholine receptors and the release of acetylcholine from the rat diaphragm

1973 • 97 citations

Functional acetylcholine receptor in PC12 cells reacts with a monoclonal antibody to brain nicotinic receptors

1987 • 93 citations

Human brain neurochemistry — Some postmortem problems

1983 • 93 citations

How many kinds of nicotinic acetylcholine receptor are there?

1989 • 92 citations

Immunohisto- and cytochemical localization of cortical nicotinic cholinoceptors in rat and man

1989 • 90 citations

Distribution of muscarinic cholinergic high and low affinity agonist binding sites: A light microscopic autoradiographic study

1984 • 89 citations

Monoclonal antibodies against the native or denatured forms of muscarinic acetylcholine receptors.

1984 • 87 citations

A monoclonal antibody interfering with binding and response of the acetylcholine receptor.

1986 • 84 citations

Neuronal acetylcholine receptors: fate of surface and internal pools in cell culture

1987 • 79 citations

Visualization of cholinoceptive neurons in the rat neocortex: colocalization of muscarinic and nicotinic acetylcholine receptors

1992 • 74 citations

Monoclonal antibodies to purified muscarinic receptor display agonist-like activity.

1984 • 70 citations

Demonstration of muscarinic acetylcholine receptor-like immunoreactivity in the rat forebrain and upper brainstem

1989 • 70 citations

Colocalization of muscarinic and nicotinic receptors in cholinoceptive neurons of the suprachiasmatic region in young and aged rats

1991 • 70 citations

Purification of muscarinic acetylcholine receptors by affinity chromatography.

1983 • 68 citations

Recent progress in identifying nicotinic cholinoceptors in mammalian brain

1987 • 66 citations

Site-directed mutagenesis and single-channel currents define the ionic channel of the nicotinic acetylcholine receptor

1989 • 65 citations

Recent advances in chemistry and pharmacology of snake toxins.

1979 • 60 citations

The Cholinergic Synapse

1988 • 59 citations

.alpha.-Bungarotoxin and the competing antibody WF6 interact with different amino acids within the same cholinergic subsite

1991 • 57 citations

Purification and characterization of an acetylcholine receptor from mammalian skeletal muscle

1977 • 54 citations

Staining of the magnocellular nuclei of the rat hypothalamus by a monoclonal antibody directed against the α-subunit of the nicotinic cholinergic receptor

1985 • 54 citations

Increased muscarinic receptor messenger RNA in Alzheimer's disease temporal cortex demonstrated by in situ hybridization histochemistry

1991 • 53 citations

Structure and Function of the Nicotinic Acetylcholine Receptor

1988 • 50 citations

Human cortical neurons contain both nicotinic and muscarinic acetylcholine receptors: An immunocytochemical double‐labeling study

1989 • 42 citations

Distribution of cholinergic receptors in the rat and human neocortex

1989 • 39 citations

Immunocytochemical visualization of muscarinic cholinoceptors in the human cerebral cortex

1990 • 39 citations

Quantitative receptor autoradiography in the human brain

1988 • 36 citations

Muscarinic cholinoceptive neurons in the frontal cortex in Alzheimer's disease

1991 • 36 citations

Anterograde vs. retrograde degeneration of the nucleus basalis medialis in Alzheimer's disease.

1987 • 34 citations

Immunochemical Studies of the Muscarinic Acetylcholine Receptor

1987 • 31 citations

The Cholinergic Receptor System in the Frontal Lobe of Alzheimer Patients

1988 • 30 citations

Monoclonal antibodies with defined specificities for Torpedo nicotinic acetylcholine receptor cross-react with Drosophila neural tissue

1987 • 29 citations

Nicotinic cholinoceptors in the rat pineal gland as analyzed by Western blot, light- and electron microscopy

1992 • 26 citations

Deficiency of acetylcholine receptors in a case of end‐plate acetylcholinesterase deficiency: A histochemical investigation

1992 • 26 citations

Cellular and subcellular localisation of muscarinic acetylcholine receptors during postnatal development of cat visual cortex using immunocytochemical procedures

1988 • 25 citations

Neurotransmitter receptors and cortical architecture.

1991 • 23 citations

Postmortem Changes in Rat Brain: Studies on Membrane‐Bound Enzymes and Receptors

1987 • 21 citations

Identification of cultured cells expressing ligand-gated cationic channels

1991 • 19 citations

Autoradiographic visualization of extrajunctional acetylcholine receptors in whole human biceps brachii muscle Changes in amyotrophic lateral sclerosis

2009 • 13 citations

Immunohistochemical localization of acetylcholine receptors at human endplates using a monoclonal antibody.

1987 • 12 citations

The nicotinic receptors in the nervous system

1988 • 10 citations

Regulation of synthesis of acetylcholine receptors

1984 • 9 citations

Central Cholinergic Transmission: The Physiological Evidence

1988 • 8 citations

Chapter 16 Synaptic adaptation in diseases of the neuromuscular junction

1990 • 4 citations

Model Cholinergic Systems: The Electromotor System of Torpedo

1988 • 3 citations

Nicotinic Acetylcholine Receptors in the Human Nervous System

1991 • 3 citations

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