Nicotinic acetylcholine binding sites in Alzheimer's disease

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects

1968 • 4,041 citations

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

1981 • 1,701 citations

Human Memory and the Cholinergic System

1974 • 1,378 citations

NEUROTRANSMITTER-RELATED ENZYMES AND INDICES OF HYPOXIA IN SENILE DEMENTIA AND OTHER ABIOTROPHIES

1976 • 1,272 citations

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin

1985 • 1,037 citations

Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's disease

1983 • 811 citations

The Cholinergic Synapse and the Site of Memory

1972 • 741 citations

Neurotransmitter enzyme abnormalities in senile dementia

1977 • 710 citations

Loss of M2 Muscarine Receptors in the Cerebral Cortex in Alzheimer's Disease and Experimental Cholinergic Denervation

1985 • 697 citations

Alzheimer's disease

1982 • 538 citations

Nicotinic Cholinergic Receptor Binding Sites in the Brain: Regulation in Vivo

1983 • 478 citations

Effects of chronic nicotine infusion on tolerance development and nicotinic receptors.

1983 • 455 citations

Aging, Alzheimer's disease, and the cholinergic system of the basal forebrain

1984 • 454 citations

Pre- and postsynaptic neurochemical alterations in Alzheimer's disease

1978 • 343 citations

Alterations in L-Glutamate Binding in Alzheimer's and Huntington's Diseases

1985 • 334 citations

ACCELERATED AGEING OR SELECTIVE NEURONAL LOSS AS AN IMPORTANT CAUSE OF DEMENTIA?

1979 • 326 citations

Regional distribution of muscarinic acetylcholine receptor in normal and Alzheimer's-type dementia brains

1977 • 313 citations

Characterization of nicotine binding in mouse brain and comparison with the binding of alpha-bungarotoxin and quinuclidinyl benzilate.

1982 • 305 citations

Oral physostigmine and lecithin improve memory in Alzheimer disease

1983 • 282 citations

Enhancement of memory processes in Alzheimer's disease with multiple- dose intravenous physostigmine

1982 • 266 citations

Nicotinic cholinergic receptors labeled by [3H]acetylcholine in rat brain.

1982 • 259 citations

Presynaptic Nicotinic Cholinergic Receptors Labeled by [³H]Acetylcholine on Catecholamine and Serotonin Axons in Brain

1984 • 235 citations

Alzheimer's disease: Choline acetyltransferase activity in brain tissue from clinical and pathological subgroups

1983 • 223 citations

Alpha-bungarotoxin binding and central nervous system nicotinic acetylcholine receptors

1981 • 219 citations

Physostigmine and Recent Memory: Effects in Young and Aged Nonhuman Primates

1979 • 205 citations

Exposure to nicotine enhances the behavioral stimulant effect of nicotine and increases binding of [3H]acetylcholine to nicotinic receptors

1985 • 205 citations

Effects of physostigmine and lecithin on memory in Alzheimer disease

1979 • 195 citations

The nucleus basalis of Meynert in neurological disease: A quantitative morphological study

1985 • 191 citations

The effects of nicotine on brain neurotransmitter systems

1982 • 191 citations

Nicotinic Stimulation of [³H]Acetylcholine Release from Mouse Cerebral Cortical Synaptosomes

1984 • 183 citations

Cholinergic receptor interactions and their effects on long-term memory processing

1981 • 170 citations

STANDARDIZATION OF A RADIOCHEMICAL ASSAY OF CHOLINE ACETYLTRANSFERASE AND A STUDY OF THE ACTIVATION OF THE ENZYME IN RABBIT BRAIN

1971 • 149 citations

Cholinergic receptor binding and autoradiography in brains of non-neurological and senile dementia of Alzheimer-type patients

1983 • 124 citations

α-Bungarotoxin binding sites in the CNS

1979 • 116 citations

Effects of Postmortem Delay and Temperature on Neurotransmitter Receptor Binding in a Rat Model of the Human Autopsy Process

1984 • 105 citations

Postmortem stability of α-bungarotoxin binding sites in mouse and human brain

1981 • 101 citations

Effect of magnocellular forebrain nuclei lesions on acetylcholine output from the cerebral cortex, electrocorticogram and behaviour.

1982 • 98 citations

Biochemical Characterization of the Nicotinic Cholinergic Receptors in Human Brain: Binding of (—)‐[³H]Nicotine

1985 • 88 citations

Muscarinic receptor compensation in hippocampus of Alzheimer patients

1983 • 85 citations

Effect of Physostigmine on Constructional and Memory Tasks in Alzheimer's Disease

1979 • 77 citations

Oral physostigmine and lecithin improve memory in Alzheimer's disease.

1983 • 76 citations

Alzheimer's disease and related dementias: selective involvement of specific neuronal systems.

1985 • 76 citations

Cholinergic receptors in aging and Alzheimer's disease

1986 • 71 citations

Cellular pathology in Alzheimer's and Parkinson's diseases

1986 • 71 citations

Autoradiographic localization of muscarinic cholinergic receptors in the hippocampus of patients with senile dementia

1982 • 61 citations

Studies on Neurotransmitter Binding in Senile Dementia

1984 • 43 citations

Cholinergic drugs and 4-aminopyridine alter hypoxic-induced behavioral deficits

1983 • 38 citations

Strategies for the Development of Animal Models of Human Memory Impairments^a

1985 • 33 citations

Studies of muscarinic and nicotinic binding sites in brain.

1980 • 27 citations

Neurologists' knowledge of medication costs

1984 • 26 citations

Neurotransmitter Receptor Alterations in Alzheimer’s Disease

1985 • 25 citations

Circadian variations in cholinergic enzymes and muscarinic receptor binding in human cerebral cortex

1977 • 24 citations