Borg proteins control septin organization and are negatively regulated by Cdc42

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

The Interaction between N-WASP and the Arp2/3 Complex Links Cdc42-Dependent Signals to Actin Assembly

1999 • 1,332 citations

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

2000 • 913 citations

Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein

2000 • 739 citations

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

1998 • 656 citations

A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases

1995 • 625 citations

Mechanism of N-Wasp Activation by Cdc42 and Phosphatidylinositol 4,5-Bisphosphate

2000 • 615 citations

Integration of Multiple Signals Through Cooperative Regulation of the N-WASP-Arp2/3 Complex

2000 • 512 citations

Plasma Membrane Compartmentalization in Yeast by Messenger RNA Transport and a Septin Diffusion Barrier

2000 • 441 citations

Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures.

1997 • 382 citations

Subunit Composition, Protein Interactions, and Structures of the Mammalian Brain sec6/8 Complex and Septin Filaments

1998 • 356 citations

The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins

1994 • 346 citations

Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells

1999 • 340 citations

A purified Drosophila septin complex forms filaments and exhibits GTPase activity.

1996 • 327 citations

A Conserved Negative Regulatory Region in αPAK: Inhibition of PAK Kinases Reveals Their Morphological Roles Downstream of Cdc42 and Rac1

1998 • 325 citations

Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’ protein

1999 • 319 citations

Compartmentalization of the Cell Cortex by Septins Is Required for Maintenance of Cell Polarity in Yeast

2000 • 309 citations

Polymerization of Purified Yeast Septins: Evidence That Organized Filament Arrays May Not Be Required for Septin Function

1998 • 276 citations

Septins: cytoskeletal polymers or signalling GTPases?

1999 • 272 citations

Role of the Yeast Gin4p Protein Kinase in Septin Assembly and the Relationship between Septin Assembly and Septin Function

1998 • 217 citations

Novel roles for mammalian septins: from vesicle trafficking to oncogenesis

2001 • 208 citations

MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)

1999 • 175 citations

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

1999 • 162 citations

t(11;22)(q23;q11.2) in acute myeloid leukemia of infant twins fuses MLL with hCDC rel , a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes

1998 • 160 citations

The Borgs, a New Family of Cdc42 and TC10 GTPase-Interacting Proteins

1999 • 145 citations

Differential localization of septins in the mouse brain

2000 • 112 citations

A New Family of Cdc42 Effector Proteins, CEPs, Function in Fibroblast and Epithelial Cell Shape Changes

2001 • 110 citations

Septins: A Highly Conserved Family of Membrane-Associated GTPases with Functions in Cell Division and Beyond

1999 • 110 citations

Genomic and Expression Analyses of Alternatively Spliced Transcripts of the MLL Septin-like Fusion Gene (MSF) That Map to a 17q25 Region of Loss in Breast and Ovarian Tumors

2000 • 94 citations

The Cdc42p GTPase Is Involved in a G2/M Morphogenetic Checkpoint Regulating the Apical-Isotropic Switch and Nuclear Division in Yeast

1999 • 92 citations

Control of mitotic events by the Cdc42 GTPase, the Clb2 cyclin and a member of the PAK kinase family

1998 • 86 citations

Rapid Identification of Protein Phosphatase 1-binding Proteins by Mixed Peptide Sequencing and Data Base Searching

1998 • 74 citations

Role of the Rab3A-Binding Domain in Targeting of Rabphilin-3A to Vesicle Membranes of PC12 Cells

1996 • 52 citations

A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11

1997 • 33 citations

Identification of a novel alternatively spliced septin

1999 • 22 citations