Cytochrome P450 2E1 genetic polymorphism and gastric cancer in Changle, Fujian Province

Genetic Polymorphisms in the 5′-Flanking Region Change Transcriptional Regulation of the Human Cytochrome P450IIE1 Gene1

1991 • 671 citations

Drug Interactions with Tobacco Smoking

1999 • 653 citations

Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers.

2000 • 583 citations

A systematic review of genetic polymorphisms and breast cancer risk.

1999 • 543 citations

Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens.

1998 • 263 citations

The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer.

1999 • 228 citations

In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus

2000 • 220 citations

Dietary habits and stomach cancer in Shanghai, China

1998 • 168 citations

Impact of genetic polymorphisms in cytochrome P450 2E1 and glutathione S-transferases M1, T1, and P1 on susceptibility to esophageal cancer among high-risk individuals in China.

2000 • 160 citations

Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the Japanese population

2001 • 152 citations

GSTT1 and GSTM1 null genotypes and the risk of gastric cancer: a case-control study in a Chinese population.

2000 • 152 citations

Susceptibility to esophageal cancer and genetic polymorphisms in glutathione S-transferases T1, P1, and M1 and cytochrome P450 2E1.

1998 • 146 citations

Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and oral cavity cancer

1999 • 138 citations

Dietary Factors and the Risk of Gastric Cancer in Mexico City

1999 • 136 citations

Role of alcohol dehydrogenase 3 and cytochrome P-4502E1 genotypes in susceptibility to cancers of the upper aerodigestive tract

2000 • 134 citations

Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1.

1999 • 128 citations

Tobacco, alcohol and the risk of gastric cancer by sub-site and histologic type

1999 • 126 citations

Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1a1, and CYP2e1

2000 • 110 citations

Genetic polymorphism of xenobiotic metabolizing enzymes among Chinese lung cancer patients

1999 • 102 citations

Characterization of cytochrome P450 expression in human oesophageal mucosa

1999 • 98 citations

Chinese Alcoholic Patients With Esophageal Cancer Are Genetically Different From Alcoholics With Acute Pancreatitis and Liver Cirrhosis

2000 • 93 citations

Genetic polymorphism of CYP2A6 in relation to cancer

1999 • 89 citations

Colorectal cancer risk in relation to genetic polymorphism of cytochrome P450 1A1, 2E1, and glutathione-S-transferase M1 enzymes.

2000 • 89 citations

Glutathione S-transferases M1, T1 genotypes and the risk of gastric cancer: A case-control study

2001 • 77 citations

Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer

2001 • 69 citations

Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice

2001 • 63 citations

Helicobacter pyloriinfection and risk of gastric cancer in Changle County, Fujian Province, China

2000 • 62 citations

[Analyses of variation trend and short-term detection of Chinese malignant tumor mortality during twenty years].

1997 • 60 citations

Role of human cytochrome P450 3A4 in metabolism of medroxyprogesterone acetate.

2000 • 58 citations

Cytochrome P450 2E1 polymorphism in gastric cancer in Brazil: case-control studies of Japanese Brazilians and non-Japanese Brazilians.

2000 • 56 citations

Polymorphic CYP genes and disease predisposition — what have the studies shown so far?

1998 • 49 citations

Update: genetic polymorphism of drug metabolizing enzymes in humans

1999 • 48 citations

Diet and gastric cancer: a case-control study in Fujian Province, China

1998 • 47 citations

Expression, deleton and mutation ofp16gene in human gastric cancer

2001 • 45 citations

Association between GSTM1*0 and squamous dysplasia of the esophagus in the high risk region of Linxian, China

2000 • 44 citations

Fish sauce and gastric cancer: an ecological study in Fujian Province, China

2000 • 36 citations

[Susceptibility to lung cancer in Chinese is associated with genetic polymorphism in cytochrome P4502E1].

2000 • 25 citations

METABOLISM OF N-NITROSOBENZYLMETHYLAMINE BY HUMAN CYTOCHROME P-450 ENZYMES

1999 • 23 citations

Associations between family history of cancer and genes coding for metabolizing enzymes (United States).

2000 • 20 citations

Nutritional and metabolic aspects of gastrointestinal cancer

1998 • 16 citations

Relationship between different sources of drinking water, water quality improvement and gastric cancer mortality in Changle County-A retrospective-cohort study in high incidence area

1998 • 15 citations

Expression, deleton and mutation of p16 gene in human gastric cancer

2001 • 13 citations

Confirmation of N-(nitrosomethyl) urea as a nitrosourea derived by nitrosation of fish sauce.

1999 • 11 citations

[Evaluation of ten-year results of cancer prevention and treatment in Changle City with high incidence of gastric cancer].

2000 • 9 citations

[Genetic polymorphisms of cytochrome P450 2E1 and glutathione S-transferase P1 and susceptibility to esophageal cancer].

1998 • 9 citations

[Application of the interaction models between the polymorphism(s) of metabolic gene(s) and environmental exposure].

2001 • 6 citations

[Cytochrome P450IA1 and the genetic susceptibility to esophageal carcinoma].

2000 • 6 citations

Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys

1999 • 5 citations