The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer.

A Heteroskedasticity-Consistent Covariance Matrix Estimator and a Direct Test for Heteroskedasticity

1980 • 25,774 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

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Promoter-specific activation of RNA polymerase II transcription by Sp1

1986 • 1,054 citations

Increased cell division as a cause of human cancer.

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Endogenous Hormones and Breast Cancer Risk

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Plasma Sex Steroid Hormone Levels and Risk of Breast Cancer in Postmenopausal Women

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The role of oestrogens and progestagens in the epidemiology and prevention of breast cancer

1988 • 647 citations

Alcohol, Height, and Adiposity in Relation to Estrogen and Prolactin Levels in Postmenopausal Women

1995 • 556 citations

Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17

1994 • 467 citations

Cloning and Sequence of the Human Gene for P450cl7 (Steroid 17α-Hydroxylase/17,20 Lyase): Similarity with the Gene for P450c21

1987 • 415 citations

Age at menarche, age at menopause, height and obesity as risk factors for breast cancer: Associations and interactions in an international case‐control study

1990 • 412 citations

Relationship Between Estrogen Levels, Use of Hormone Replacement Therapy, and Breast Cancer

1998 • 397 citations

Expression of Bovine 17α-Hydroxylase Cytochrome P-450 cDNA in Nonsteroidogenic (COS 1) Cells

1986 • 389 citations

Breast Cancer Epidemiology: Summary and Future Directions

1993 • 351 citations

Reproducibility of plasma hormone levels in postmenopausal women over a 2-3-year period.

1995 • 347 citations

Estrogen Receptor Expression in Benign Breast Epithelium and Breast Cancer Risk

1998 • 253 citations

A polymorphism in the CYP17 gene increases the risk of breast cancer.

1997 • 250 citations

Cytochrome P450c17alpha gene (CYP17) polymorphism is associated with serum estrogen and progesterone concentrations.

1998 • 243 citations

Dysregulation of cytochrome P450c17α as the cause of polycystic ovarian syndrome

1991 • 224 citations

The interconversion and aromatization of androgens by human adipose tissue

1979 • 144 citations

No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer

1998 • 118 citations

17α-Hydroxylase/17,20-lyase defects

1995 • 103 citations

CYP17 genotype and breast cancer risk.

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Hypersecretion of androgens by polycystic ovaries: The role of genetic factors in the regulation of cytochrome P450c17α

1996 • 36 citations

Aromatase activity and CYP19 gene expression in breast cancers

1996 • 24 citations