Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and oral cavity cancer

The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I

1995 • 3,492 citations

Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism

1994 • 1,319 citations

Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility.

1997 • 761 citations

Genetic Polymorphisms in the 5′-Flanking Region Change Transcriptional Regulation of the Human Cytochrome P450IIE1 Gene1

1991 • 671 citations

Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy.

1988 • 465 citations

Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population

1994 • 440 citations

Cytochrome P450IIe1: Roles in Nitrosamine Metabolism and Mechanisms of Regulation

1990 • 361 citations

Alcohol, smoking, social and occupational factors in the aetiology of cancer of the oral cavity, pharynx and larynx

1984 • 314 citations

Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma

1996 • 256 citations

The CYP1A1 gene and cancer susceptibility

1993 • 210 citations

Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer.

1997 • 188 citations

CYP1A1 and GSTM1 polymorphisms and oral cancer risk.

1997 • 159 citations

Interindividual variability of chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms*

1995 • 154 citations

Characterization of purified human recombinant cytochrome P4501A1-Ile462 and -Val462: assessment of a role for the rare allele in carcinogenesis.

1996 • 146 citations

New Strategy for Detection of Aldh2 Mutant

1993 • 145 citations

Glutathione S-transferase genotypes as risk factors for head and neck cancer

1995 • 126 citations

Genetic Polymorphisms of Tobacco- and Alcohol-Related Metabolizing Enzymes and Human Esophageal Squamous Cell Carcinoma Susceptibility

1997 • 118 citations

Pstl and Rsal RFLPs in complete linkage disequilibrium at the CYP2E gene

1990 • 97 citations

Cytochrome P4501A1 gene polymorphism and homozygous deletion of the glutathione S-transferase M1 gene in urothelial cancer patients

1995 • 79 citations

GSTM1 gene polymorphism as a possible marker for susceptibility to head and neck cancers among Japanese smokers

1997 • 62 citations