Chapter 46: Cholinergic receptor subtypes and REM sleep in animals and normal controls

Brain stem reticular formation and activation of the EEG

1949 • 4,188 citations

Central cholinergic pathways in the rat: An overview based on an alternative nomenclature (Ch1–Ch6)

1983 • 2,305 citations

Brainstem Control of Wakefulness and Sleep

1990 • 1,188 citations

Smoking, Smoking Cessation, and Major Depression

1990 • 1,174 citations

Nucleus basalis and thalamic control of neocortical activity in the freely moving rat

1988 • 1,035 citations

The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat

1981 • 966 citations

Distribution of cholinergic neurons in rat brain: Demonstrated by the immunocytochemical localization of choline acetyltransferase

1983 • 964 citations

Depression and the Dynamics of Smoking

1990 • 896 citations

Nicotine Dependence, Major Depression, and Anxiety in Young Adults

1991 • 637 citations

Network modulation of a slow intrinsic oscillation of cat thalamocortical neurons implicated in sleep delta waves: cortically induced synchronization and brainstem cholinergic suppression

1991 • 479 citations

The sleep-waking cycle

1972 • 476 citations

Paradoxical sleep and its chemical/structural substrates in the brain

1991 • 402 citations

A cholinergic mechanism in the brainstem reticular formation: Induction of paradoxical sleep

1964 • 394 citations

Medullary regions mediating atonia

1988 • 362 citations

Neurotoxic lesions of the dorsolateral pontomesencephalic tegmentum-cholinergic cell area in the cat. II. Effects upon sleep-waking states

1988 • 346 citations

Direct autoradiographic determination of M1 and M2 muscarinic acetylcholine receptor distribution in the rat brain: Relation to cholinergic nuclei and projections

1986 • 326 citations

Limbic cholinergic pathways involved in sleep and emotional behavior

1963 • 307 citations

Cholinergic projections from the midbrain and pons to the thalamus in the rat, identified by combined retrograde tracing and choline acetyltransferase immunohistochemistry

1985 • 293 citations

Distribution of acetylcholine and catecholamine neurons in the cat brainstem: A choline acetyltransferase and tyrosine hydroxylase immunohistochemical study

1987 • 284 citations

Cholinergic projections from the laterodorsal and pedunculopontine tegmental nuclei to the pontine gigantocellular tegmental field in the cat

1988 • 245 citations

Pontine regulation of REM sleep components in cats: integrity of the pedunculopontine tegmentum (PPT) is important for phasic events but unnecessary for atonia during REM sleep

1992 • 241 citations

Sleep cycle control and cholinergic mechanisms: Differential effects of carbachol injections at pontine brain stem sites

1975 • 186 citations

Enhancement of acetylcholine release during paradoxical sleep in the dorsal tegmental field of the cat brain stem

1990 • 175 citations

Microinjection of neostigmine into the pontine reticular formation of cats enhances desynchronized sleep signs.

1984 • 160 citations

Cigarette Smoking Associated with Sleep Difficulty

1980 • 159 citations

Induction of both emotional behavior and a novel form of REm sleep by chemical stimulation applied to cat mesencephalon

1969 • 146 citations

Effect of specific M1, M2 muscarinic receptor agonists on REM sleep generation

1989 • 145 citations

Functional role of 5-HT2 receptors in the regulation of sleep and wakefulness in the rat

1989 • 139 citations

Pontine neuronal response to local cholinergic infusion: Relation to REM sleep

1986 • 116 citations

Continuous pontine cholinergic microinfusion via mini-pump induces sustained alterations in rapid eye movement (REM) sleep

1986 • 111 citations

Acetylcholine and the Regulation of REM Sleep: Basic Mechanisms and Clinical Implications for Affective Illness and Narcolepsy

1987 • 110 citations

Cholinergic neurons from the dorsolateral pons project to the medial pons: A WGA-HRP and choline acetyltransferase immunohistochemical study

1988 • 109 citations

Antinociception after nicotine administration into the mesopontine tegmentum of rats: evidence for muscarinic actions.

1989 • 100 citations

Role of Cholinergic Mechanisms in States of Wakefulness and Sleep

1968 • 98 citations

The Cholinergic Rapid Eye Movement Induction Test With Arecoline in Depression

1991 • 97 citations

Cholinergic activation of medial pontine reticular formation neurons in vitro

1989 • 97 citations

Enhancement of desynchronized sleep signs after pontine microinjection of the muscarinic agonist bethanechol

1983 • 97 citations

Development and use of pharmacological probes of the CNS in man: evidence of cholinergic abnormality in primary affective illness.

1980 • 87 citations

Increasing PGO spike density by auditory stimulation increases the duration and decreases the latency of rapid eye movement (REM) sleep

1983 • 84 citations

Affinity and selectivity of biperiden enantiomers for muscarinic receptor subtypes

1988 • 81 citations

A photographic perspective on the origins, form, course and relations of the acetylcholinesterase-containing fibres of the dorsal tegmental pathway in the rat brain

1985 • 81 citations

Muscarinic receptor subclassification and G-proteins: Significance for lithium action in affective disorders and for the treatment of the extrapyramidal side effects of neuroleptics

1989 • 80 citations

Rapid-eye-movement sleep deprivation decreases the density of 3H-dihydroalprenolol and 3H-imipramine binding sites in the rat cerebral cortex

1980 • 77 citations

The effects of scopolamine on sleep and mood in depressed patients with a history of alcoholism and a normal comparison group

1991 • 73 citations

Effects of RS 86, an orally active cholinergic agonist, on sleep in man

1984 • 65 citations

Evidence for the Role of Serotonin in the Regulation of Slow Wave Sleep in Schizophrenia

1991 • 60 citations

Cholinergic antagonists and REM sleep generation

1991 • 59 citations

Does REM sleep deprivation induce subsensitivity of presynaptic dopamine or postsynaptic acetylcholine receptors in the rat brain?

1987 • 57 citations

Descending projections from the dorsolateral pontine tegmentum to the paramedian reticular nucleus of the caudal medulla in the cat

1990 • 56 citations

Sleep and other behavioural effects induced by acetylcholinic stimulation of basal temporal cortex and striate structures

1967 • 54 citations

Method of administration determines the effect of naloxone on pain

1986 • 54 citations

The blockage of ponto-geniculo-occipital waves in the cat lateral geniculate nucleus by nicotinic antagonists

1988 • 52 citations

REM sleep deprivation decreases apomorphine-induced stimulation of locomotor activity but not stereotyped behavior in mice

1992 • 51 citations

Long-term enhancement of REM sleep following cholinergic stimulation

1991 • 48 citations

Pilocarpine, an orally active muscarinic cholinergic agonist, induces REM sleep and reduces delta sleep in normal volunteers

1990 • 43 citations

Microinjections of nicotine in the medial pontine reticular formation elicits REM sleep

1990 • 34 citations

The effects of REM sleep deprivation on striatal dopamine receptor sites

1986 • 34 citations

Rapid-eye movement sleep and muscarinic receptor binding in rats are augmented during withdrawal from chronic scopolamine treatment

1986 • 33 citations

Effect of REM sleep deprivation on rat brain acetylcholinesterase

1991 • 33 citations

Dose dependent inhibition of REM sleep in normal volunteers by biperiden, a muscarinic antagonist

1991 • 32 citations

Cholinergic reduction of REM sleep duration is reverted by auditory stimulation

1986 • 29 citations

The relative effects of selective M1 muscarinic antagonists on rapid eye movement sleep

1993 • 28 citations

Pontine cholinergic neurons simultaneously innervate two thalamic targets

1990 • 24 citations

The cholinergic REM sleep induction test with pilocarpine in mildly depressed patients and normal controls

1993 • 23 citations

REM sleep deprivation induces a decrease in norepinephrine-stimulated 3H-cyclic AMP accumulation in slices from rat brain

1986 • 23 citations

Differential effects of cholinergic antagonists on REM sleep components.

1990 • 23 citations

Chapter 42 Acetylcholine and acetylcholine receptor subtypes in REM sleep generation

1990 • 21 citations

Effects of auditory stimulation during rapid eye movement sleep in healthy volunteers and depressed patients

1991 • 20 citations

Quantitative autoradiographic localization of the M1 and M2 subtypes of muscarinic acetylcholine receptors in the monkey brain.

1989 • 19 citations

Development of tolerance after repeated administration of a selective muscarinic M1 antagonist biperiden in healthy human volunteers

1993 • 18 citations

Biperiden administration in normal sleep and after rapid eye movement sleep deprivation in healthy volunteers.

1991 • 17 citations

Short-term REM sleep deprivation increases acetylcholinesterase activity in the medulla of rats

1991 • 14 citations

Sleep and other behavioural responses induced by acetylcholinic stimulation of frontal and mesial cortex

1967 • 14 citations

Biperiden Administration During REM Sleep Deprivation Diminished the Frequency of REM Sleep Attempts

1992 • 13 citations

Effects of biperiden on sleep at baseline and after 72 h of REM sleep deprivation in the cat

1992 • 12 citations

Effects of Physostigmine Infusion on Healthy Volunteers Deprived of Rapid Eye Movement Sleep

1989 • 8 citations

Rapid eye movement (REM) sleep increases by auditory stimulation reverted with biperiden administration in normal volunteers.

1991 • 7 citations

Muscarinic receptor binding in forebrain and cerebellum during sleep-waking states in the rat.

1990 • 3 citations

Deleted Work

1955 • 0 citations