The relative effects of selective M1 muscarinic antagonists on rapid eye movement sleep

Sleep Cycle Oscillation: Reciprocal Discharge by Two Brainstem Neuronal Groups

1975 • 1,216 citations

Neuronal excitability modulation over the sleep cycle: a structural and mathematical model

1975 • 636 citations

Network modulation of a slow intrinsic oscillation of cat thalamocortical neurons implicated in sleep delta waves: cortically induced synchronization and brainstem cholinergic suppression

1991 • 479 citations

Localization of a family of muscarinic receptor mRNAs in rat brain

1988 • 472 citations

Direct autoradiographic determination of M1 and M2 muscarinic acetylcholine receptor distribution in the rat brain: Relation to cholinergic nuclei and projections

1986 • 326 citations

Evolving concepts of sleep cycle generation: From brain centers to neuronal populations

1986 • 321 citations

Autoradiographic localization of M1 and M2 muscarine receptors in the rat brain

1986 • 312 citations

Limbic cholinergic pathways involved in sleep and emotional behavior

1963 • 307 citations

Effect of specific M1, M2 muscarinic receptor agonists on REM sleep generation

1989 • 145 citations

Acetylcholine and the Regulation of REM Sleep: Basic Mechanisms and Clinical Implications for Affective Illness and Narcolepsy

1987 • 110 citations

Affinity and selectivity of biperiden enantiomers for muscarinic receptor subtypes

1988 • 81 citations

Muscarinic receptor subclassification and G-proteins: Significance for lithium action in affective disorders and for the treatment of the extrapyramidal side effects of neuroleptics

1989 • 80 citations

The effects of scopolamine on sleep and mood in depressed patients with a history of alcoholism and a normal comparison group

1991 • 73 citations

M2 muscarinic receptors mediate pressor responses to cholinergic agonists in the ventrolateral medullary pressor area

1988 • 72 citations

Muscarinic M1, M2 receptor binding. Relationship with functional efficacy

1988 • 62 citations

Expression of a cloned muscarinic receptor in A9 L cells.

1987 • 43 citations

Pharmacokinetics of trihexyphenidyl after short‐term and long‐term administration to dystonic patients

1985 • 35 citations

State‐dependent hypotonia in posterior cricoarytenoid muscles of the larynx caused by cholinoceptive reticular mechanisms

1989 • 34 citations

Rapid-eye movement sleep and muscarinic receptor binding in rats are augmented during withdrawal from chronic scopolamine treatment

1986 • 33 citations

Biperiden effects and plasma levels in volunteers

1984 • 33 citations

Dose dependent inhibition of REM sleep in normal volunteers by biperiden, a muscarinic antagonist

1991 • 32 citations

Effects of Fasting on Biperiden Pharmacokinetics in the Rat

1987 • 26 citations

Effect of fat tissue volume on the distribution kinetics of biperiden as a function of age in rats.

1990 • 24 citations

Differential effects of cholinergic antagonists on REM sleep components.

1990 • 23 citations

Cholinergic stimulation of drinking from the lateral hypothalamus: Indications for M2 muscarinic receptor mediation

1987 • 19 citations

Biperiden administration in normal sleep and after rapid eye movement sleep deprivation in healthy volunteers.

1991 • 17 citations

Involvement of M1-muscarinic receptors in the excitation of neocortical neurones by acetylcholine

1987 • 9 citations