Promoter accessibility within the environment of the MHC is affected in class II-deficient combined immunodeficiency.

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1989 • 972 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

Sequences and Factors: A Guide to MHC Class-II Transcription

1992 • 540 citations

Regulation of Major Histocompatibility Complex Class-II Genes: X, Y and Other Letters of the Alphabet

1990 • 470 citations

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter

1990 • 440 citations

Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

1991 • 372 citations

Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors

1987 • 356 citations

Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X

1988 • 275 citations

Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains.

1991 • 269 citations

A yeast protein that influences the chromatin structure of UASG and functions as a powerful auxiliary gene activator.

1990 • 229 citations

A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes

1985 • 191 citations

Constitutive and metal-inducible protein:DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting.

1988 • 176 citations

In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome

1991 • 175 citations

Role of trans-activating proteins in the generation of active chromatin at the PHO5 promoter in S. cerevisiae.

1990 • 143 citations

Upstream DNA sequences required for tissue-specific expression of the HLA-DR alpha gene.

1987 • 126 citations

Class II-antigen-negative patient and mutant B-cell lines represent at least three, and probably four, distinct genetic defects defined by complementation analysis.

1991 • 125 citations

Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors.

1990 • 121 citations

A defect in the regulation of major histocompatibility complex class II gene expression in human HLA-DR negative lymphocytes from patients with combined immunodeficiency syndrome.

1985 • 86 citations

Congenital immunodeficiencies associated with absence of HLA class II antigens on lymphocytes result from distinct mutations in trans-acting factors

1989 • 82 citations

Sequence Elements Required for Activity of a Murine Major Histocompatibility Complex Class II Promoter Bind Common and Cell-Type-Specific Nuclear Factors

1990 • 68 citations

Two distinct genetic loci regulating class II gene expression are defective in human mutant and patient cell lines.

1988 • 46 citations

Inherited immunodeficiency with a defect in a major histocompatibility complex class II promoter-binding protein differs in the chromatin structure of the HLA-DRA gene.

1989 • 41 citations

Inherited Immunodeficiency with a Defect in a Major Histocompatibility Complex Class II Promoter-Binding Protein Differs in the Chromatin Structure of the HLA-DRA Gene

1989 • 13 citations