Correlation of Bcl-2 Rearrangement With Clinical Characteristics and Outcome in Indolent Follicular Lymphoma

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Regression Models and Life-Tables

1992 • 27,454 citations

Regression Models and Life-Tables

1972 • 27,145 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group [see comments]

1994 • 6,495 citations

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

A generalized Wilcoxon test for comparing arbitrarily singly-censored samples

1965 • 3,333 citations

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1988 • 3,194 citations

Involvement of the bcl -2 Gene in Human Follicular Lymphoma

1985 • 1,797 citations

Cloning of the Chromosome Breakpoint of Neoplastic B Cells with the t(14;18) Chromosome Translocation

1984 • 1,761 citations

Molecular thanatopsis: a discourse on the BCL2 family and cell death

1996 • 1,412 citations

Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma.

1986 • 1,118 citations

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

1985 • 972 citations

Distinctive Chromosomal Abnormalities in Histologic Subtypes of Non-Hodgkin's Lymphoma

1982 • 642 citations

Detection of Minimal Residual Cells Carrying the t(14;18) by DNA Sequence Amplification

1987 • 426 citations

Lymphoma-associated translocation t(14;18) in blood B cells of normal individuals

1995 • 426 citations

Prognostic significance of bcl-2 protein expression in aggressive non- Hodgkin's lymphoma. Groupe d'Etude des Lymphomes de l'Adulte (GELA)

1996 • 424 citations

Prognostic significance of bcl-2 protein expression in aggressive non- Hodgkin's lymphoma. Groupe d'Etude des Lymphomes de l'Adulte (GELA)

1996 • 419 citations

p53 mutation is associated with progression in follicular lymphomas

1993 • 394 citations

Rearrangement of the bcl-6 Gene as a Prognostic Marker in Diffuse Large-Cell Lymphoma

1994 • 387 citations

Regulation of Lymphocyte Survival by the BCL-2 Gene Family

1995 • 380 citations

BCL2 translocation frequency rises with age in humans.

1994 • 372 citations

Detection of a second t(14;18) breakpoint cluster region in human follicular lymphomas.

1986 • 346 citations

Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma

1993 • 340 citations

Prognostic significance of BCL-2 expression and bcl-2 major breakpoint region rearrangement in diffuse large cell non-Hodgkin's lymphoma: a British National Lymphoma Investigation Study

1996 • 322 citations

bcl-2and Other Genomic Alterations in the Prognosis of Large-Cell Lymphoma

1989 • 309 citations

p16INK4a Gene Inactivation by Deletions, Mutations, and Hypermethylation Is Associated With Transformed and Aggressive Variants of Non-Hodgkin's Lymphomas

1998 • 300 citations

Expression of Bcl-2 and Bcl-2-Ig fusion transcripts in normal and neoplastic cells.

1987 • 297 citations

Fludarabine, mitoxantrone, and dexamethasone: an effective new regimen for indolent lymphoma.

1996 • 273 citations

Prognostic value of chromosomal abnormalities in follicular lymphoma

1994 • 263 citations

MYC rearrangements in histologically progressed follicular lymphomas

1992 • 240 citations

Comparison of Cytogenetic Analysis, Southern Analysis, and Polymerase Chain Reaction for the Detection of t(14; 18) in Follicular Lymphoma

1995 • 228 citations

Applicability of the International Index for aggressive lymphomas to patients with low-grade lymphoma.

1994 • 207 citations

BCL-2/JH rearrangements in circulating B cells of healthy blood donors and patients with nonmalignant diseases.

1996 • 181 citations

Cytogenetic Abnormalities Predict Clinical Outcome in Non-Hodgkin Lymphoma

1988 • 120 citations

Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma

1992 • 97 citations

Detection of occult lymphoma in the peripheral blood and bone marrow of patients with untreated early-stage and advanced-stage follicular lymphoma.

1993 • 74 citations

The management of follicular lymphoma

1991 • 68 citations

Sensitive and reproducible detection of occult disease in patients with follicular lymphoma by PCR amplification of t(14;18) both pre- and post-treatment.

1993 • 52 citations

Intensive conventional-dose chemotherapy for stage IV low-grade lymphoma: High remission rates and reversion to negative of peripheral blood bcl-2 rearrangement

1994 • 46 citations

Detection of bcl-2/JH rearrangement in follicular and diffuse lymphoma: concordant results of peripheral blood and bone marrow analysis at diagnosis

1993 • 42 citations

BCL2 gene activation and protein expression in follicular lymphoma: a report on 64 cases.

1993 • 38 citations

Cisplatin and carboplatin in combination for the treatment of stage IV ovarian carcinoma

1991 • 33 citations

Incidence and prognostic significance of t(14; 18) translocation in follicle center cell lymphoma of low and high grade

1995 • 32 citations

Molecular aspects of chromosomal translocation t(14;18).

1993 • 21 citations