MYC rearrangements in histologically progressed follicular lymphomas

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1988 • 3,194 citations

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1986 • 1,232 citations

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around Jh on chromosome 14 and near a transcriptional unit on 18

1985 • 1,188 citations

The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation

1986 • 927 citations

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2

1990 • 910 citations

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

1991 • 876 citations

Molecular Analysis of the T(14;18) Chromosomal Translocation in Malignant Lymphomas

1987 • 701 citations

Multiple Recurrent Genomic Defects in Follicular Lymphoma

1987 • 535 citations

The Pathogenesis of Burkitt's Lymphoma

1990 • 477 citations

Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma

1986 • 332 citations

A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production

1986 • 331 citations

Frequent c-myc oncogene activation and infrequent presence of Epstein- Barr virus genome in AIDS-associated lymphoma

1988 • 260 citations

Activation of thec-mycOncogene in a Precursor-B-Cell Blast Crisis of Follicular Lymphoma, Presenting as Composite Lymphoma

1988 • 258 citations

Aggressive peripheral T-cell lymphomas containing Epstein-Barr viral DNA: a clinicopathologic and molecular analysis

1991 • 244 citations

Histologic progression in non-Hodgkin's lymphoma

1982 • 236 citations

Mutations in the First Exon Are Associated with Altered Transcription of c- myc in Burkitt Lymphoma

1987 • 228 citations

A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia.

1984 • 227 citations

Histologic conversion in the non-Hodgkin's lymphomas.

1983 • 225 citations

Frequent c-myc oncogene activation and infrequent presence of Epstein- Barr virus genome in AIDS-associated lymphoma

1988 • 224 citations

Aggressive peripheral T-cell lymphomas containing Epstein-Barr viral DNA: a clinicopathologic and molecular analysis

1991 • 221 citations

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching.

1986 • 220 citations

Cytogenetic analysis of 434 consecutively ascertained specimens of non- Hodgkin's lymphoma: clinical correlations

1991 • 217 citations

Spatial and temporal pattern of cellular myc oncogene expression in developing human placenta: Implications for embryonic cell proliferation

1984 • 206 citations

Clonal analysis of transplant-associated lymphoproliferations based on the structure of the genomic termini of the Epstein-Barr virus

1988 • 189 citations

Lymphoproliferative diseases in immunocompromised hosts: the role of Epstein-Barr virus.

1987 • 183 citations

Histological transformation of non-hodgkin's lymphoma.A prospective study

1979 • 177 citations

An autopsy study of histologic progression in non-Hodgkin's lymphomas 192 cases from the national cancer institute

1983 • 155 citations

Transcription and Promoter Usage of the myc Gene tn Normal Somatic and Spermatogenic Cells

1984 • 150 citations

Non-hodgkin's lymphoma.A study of the evolution of the disease based upon 92 autopsied cases

1979 • 142 citations

MYC rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas

1991 • 123 citations

Activation of MYC in a masked t(8;17) translocation results in an aggressive B-cell leukemia.

1989 • 122 citations

Evolution of B-cell malignancy: pre-B-cell leukemia resulting from MYC activation in a B-cell neoplasm with a rearranged BCL2 gene.

1988 • 121 citations

Sequential bcl-2 and c-myc oncogene rearrangements associated with the clinical transformation of non-Hodgkin's lymphoma.

1989 • 119 citations

Low-grade lymphomas. Expression of developmentally regulated B-cell antigens.

1984 • 116 citations

Clinical, morphologic, and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q32) or t(8;22)(q24;q11)

1990 • 113 citations

Single cell origin of bigenotypic and biphenotypic B cell proliferations in human follicular lymphomas.

1988 • 108 citations

The gene located at chromosome 18 band q21 is rearranged in uncultured diffuse lymphomas as well as follicular lymphomas

1987 • 105 citations

Intermediate- to high-grade histology of lymphomas carrying t(14;18) is associated with additional nonrandom chromosome changes

1987 • 98 citations

Histogenetic correlations between subcategories of small noncleaved cell lymphomas

1992 • 95 citations

Clonal analysis of transplant-associated lymphoproliferations based on the structure of the genomic termini of the Epstein-Barr virus

1988 • 93 citations

Follicular low‐grade non‐Hodgkin's lymphoma: Long‐term outcome with or without tumor progression

1989 • 88 citations

A chromosome 12 coding region is juxtaposed to the MYC protooncogene locus in a t(8; 12)(q24;q22) translocation in a case of B‐cell chronic lymphocytic leukemia

1991 • 87 citations

Common ALL with pre-B-cell features showing (8;14) and (14;18) chromosome translocations

1983 • 87 citations

Malignant lymphomas of follicular center cell origin in humans. V. incidence, clinical features, and prognostic implications of transformation of small cleaved cell nodular lymphoma

1984 • 86 citations

Cytogenetic analysis of 147 cases of non‐Hodgkin's lymphoma: non‐random chromosomal abnormalities and histological correlations

1990 • 83 citations

Correlation of Secondary Cytogenetic Abnormalities With Histologic Appearance in Non-Hodgkin's Lymphomas Bearing t(14;18)(q32;q21)

1988 • 77 citations

Terminal Deoxynucleotidyl Transferase in Non-Hodgkin's Lymphoma

1983 • 64 citations

Evidence of c-myc gene abnormalities in mediastinal large B-cell lymphoma of young adult age [see comments]

1991 • 58 citations

De novo acute B-cell leukemia with translocation t(14;18): an entity with a poor prognosis.

1991 • 55 citations

Clonal evolution of t(14;18) follicular lymphomas demonstrated by immunoglobulin genes and the 18q21 major breakpoint region.

1987 • 53 citations

Molecular cloning of a DNA fragment from human chromosome 14(14q11) involved in T-cell malignancies.

1985 • 48 citations

Sequence analysis of the MYC oncogene involved in the t(8;14)(q24;q11) chromosome translocation in a human leukemia T-cell line indicates that putative regulatory regions are not altered.

1988 • 45 citations

Acute Lymphoblastic Leukemia of Burkitt’s Type (L3 ALL) with 8;22 and 14; 18 Translocations and Absent Surface Immunoglobulins

1986 • 37 citations

Translocation (14; 18) and (8; 22) in three patients with acute leukemia/lymphoma following centrocytic/centroblastic non-Hodgkin's lymphoma

1991 • 37 citations

Clustered somatic mutations in and around first exon of non-rearranged c-myc in Burkitt lymphoma with t(8;22) translocation

1987 • 33 citations

Alterations in immunoglobulin genes reveal the origin and evolution of monotypic and bitypic B cell lymphomas.

1989 • 29 citations

Simultaneous presence of translocations t(14;18) and t(2;8) in a case of chronic lymphocytic leukemia

1986 • 22 citations

Cytogenetic analysis of 434 consecutively ascertained specimens of non- Hodgkin's lymphoma: clinical correlations

1991 • 16 citations

Molecular structure of double reciprocal translocations: significance in B-cell lymphomagenesis.

1991 • 15 citations

Somatic rearrangement of the c‐myc oncogene in primary human diffuse large‐cell lymphoma

1986 • 14 citations

Genomic rearrangement of the c-myc proto-oncogene in non-AIDS-related lymphoma in Japan.

1991 • 10 citations

Common ALL with pre-B-cell features showing (8;14) and (14;18) chromosome translocations

1983 • 9 citations

Immunological and molecular studies in a case of follicular lymphoma with an extra chromosome 12 and t(2;8) translocation.

1988 • 8 citations

MYC rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas

1991 • 7 citations

Involvement of theBCL2Gene in 131 Cases of Non-Hodgkin's B Lymphomas: Analysis of Correlations with Immunological Findings and Cell Cycle

1991 • 7 citations

Histogenetic correlations between subcategories of small noncleaved cell lymphomas

1992 • 5 citations