Activation of NADPH oxidase by purine and pyrimidine nucleotides involves G proteins and is potentiated by chemotactic peptides

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

Is there a basis for distinguishing two types of P2-purinoceptor?

1985 • 1,353 citations

The O2−-forming NADPH oxidase of the phagocytes: nature, mechanisms of activation and function

1986 • 665 citations

Factors influencing platelet function: adhesion, release, and aggregation.

1970 • 635 citations

Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin

1984 • 418 citations

Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils.

1985 • 345 citations

Inhibition by islet-activating protein of a chemotactic peptide-induced early breakdown of inositol phospholipids and Ca2+ mobilization in guinea pig neutrophils.

1985 • 250 citations

P2-purinergic receptors are coupled to two signal transduction systems leading to inhibition of cAMP generation and to production of inositol trisphosphate in rat hepatocytes.

1987 • 213 citations

Cyclic Nucleotide-induced Maturation of Human Promyelocytic Leukemia Cells

1982 • 213 citations

Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein.

1987 • 188 citations

Intracellular Ca2+ mobilization activated by extracellular ATP in Ehrlich ascites tumor cells.

1985 • 159 citations

Role of a guanine nucleotide regulatory protein in the activation of phospholipase C by different chemoattractants.

1987 • 147 citations

Receptor-cytoskeleton interactions and membrane traffic may regulate chemoattractant-induced superoxide production in human granulocytes.

1986 • 144 citations

Adenosine triphosphate stimulates inositol phospholipid metabolism and prostacyclin formation in adrenal medullary endothelial cells by means of P2-purinergic receptors.

1987 • 141 citations

Purification and immunochemical characterization of the major pertussis‐toxin‐sensitive guanine‐nucleotide‐binding protein of bovine‐neutrophil membranes

1987 • 110 citations

Actions of extracellular UTP and ATP in perfused rat liver

1987 • 107 citations

The effect of six prostaglandins, prostacyclin and iloprost on generation of superoxide anions by human polymorphonuclear leukocytes stimulated by zymosan or formyl-methionyl-leucyl-phenylalanine

1987 • 106 citations

Evidence for a vasoconstriction-mediating receptor for UTP, distinct from the P2 purinoceptor, in rabbit ear artery

1987 • 105 citations

Fatty‐acid‐induced activation of NADPH oxidase in plasma membranes of human neutrophils depends on neutrophil cytosol and is potentiated by stable guanine nucleotides

1987 • 97 citations

ATP induces transient elevations of [Ca2+]i in human neutrophils and primes these cells for enhanced O2- generation.

1988 • 95 citations

Adenine-, guanine- and uridine-5'-phosphonucleotides in blood platelets and storage organelles of various species.

1971 • 93 citations

Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils

1986 • 92 citations

A pertussis toxin-sensitive GTP-binding protein in the human neutrophil regulates multiple receptors, calcium mobilization, and lectin-induced capping.

1985 • 83 citations

P_2Y‐purinoceptor regulation of surfactant secretion from rat isolated alveolar type II cells is associated with mobilization of intracellular calcium

1987 • 75 citations

Stimulus response coupling in the human neutrophil. Differential requirements for receptor occupancy in neutrophil responses to a chemoattractant.

1984 • 68 citations

The role of nucleoside‐diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides

1988 • 67 citations

Receptor-specific threshold effects of cyclic AMP are involved in the regulation of enzyme release and superoxide production from human neutrophils

1985 • 56 citations

Reversible activation of NADPH oxidase in membranes of HL-60 human leukemic cells

1987 • 56 citations

Mechanisms of Regulating the Respiratory Burst in Leukocytes

1984 • 49 citations

Studies with protein kinase C inhibitors presently available cannot elucidate the role of protein kinase C in the activation of NADPH oxidase

1988 • 43 citations

Mechanisms of the contractile effect induced by uridine 5-triphosphate in canine cerebral arteries.

1983 • 42 citations

Endothelium-Dependent Relaxation by Uridine Tri- and Diphosphate in Isolated Human Pial Vessels

1987 • 36 citations

Different sensitivities of the responses of human neutrophils stimulated with immune complex and C5a anaphylatoxin to pertussis toxin

1988 • 24 citations

Activation of the human neutrophil respiratory burst with zymosan-activated serum

1984 • 11 citations