Receptor-specific threshold effects of cyclic AMP are involved in the regulation of enzyme release and superoxide production from human neutrophils

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

1968 • 2,659 citations

Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.

1983 • 938 citations

Mechanisms of Lysosomal Enzyme Release from Human Leukocytes II. EFFECTS OF cAMP AND cGMP, AUTONOMIC AGONISTS, AND AGENTS WHICH AFFECT MICROTUBULE FUNCTION

1974 • 567 citations

The role of cyclic AMP in the chemotactic responsiveness and spontaneous motility of rabbit peritoneal neutrophils. The inhibition of neutrophil movement and the elevation of cyclic AMP levels by catecholamines, prostaglandins, theophylline and cholera toxin.

1975 • 271 citations

Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms.

1983 • 225 citations

Role of cell surface contact in the kinetics of superoxide production by granulocytes.

1983 • 126 citations

The role of agonists that activate adenylate cyclase in the control of cAMP metabolism and enzyme release by human polymorphonuclear leukocytes.

1980 • 92 citations

Chemotactic Factor-Induced Generation of Superoxide Radicals by Human Neutrophils: Evidence for the Role of Sodium

1979 • 74 citations

Stimuli which provoke secretion of azurophil enzymes from human neutrophils induce increments in adenosine cyclic 3′-5′-monophosphate

1981 • 73 citations

Anti-inflammatory effects of prostaglandin E1: in vivo modulation of the formyl peptide chemotactic receptor on the rat neutrophil.

1983 • 68 citations

Isoproterenol inhibition of isolated human neutrophil function

1984 • 65 citations

Changes in protein phosphorylation in guinea pig polymorphonuclear leukocytes by treatment with membrane-perturbing agents which stimulate superoxide anion production

1984 • 50 citations

Chemotactic factors induced vimentin phosphorylation in rabbit peritoneal neutrophil.

1984 • 46 citations

Endogenous substrates for cyclic AMP-dependent and calcium-dependent protein phosphorylation in rabbit peritoneal neutrophils

1983 • 44 citations

The beta-adrenergic receptor in the human neutrophil plasma membrane: receptor-cyclase uncoupling is associated with amplified GTP activation.

1984 • 23 citations

Identification of receptor regulatory proteins, membrane glycoproteins, and functional characteristics of adenylate cyclase in vesicles derived from the human neutrophil

1984 • 21 citations

Phosphorylation of myosin light chain in intact pig leukocytes stimulated by phorbol 12-myristate 13-acetate

1984 • 17 citations

Morphological Changes in Human Polymorphonuclear Leukocytes Induced by C3a in the Presence and Absence of Cytochalasin B

1982 • 12 citations

Concanavalin-A-Induced Suppressor Cell Activity in Idiopathic Membranous Nephropathy

1982 • 6 citations