Hereditary colon cancer syndromes: polyposis and nonpolyposis (Lynch syndromes I & II) variants

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

1980 • 8,270 citations

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications

1983 • 1,856 citations

Multiple cutaneous and subcutaneous lesions occurring simultaneously with hereditary polyposis and osteomatosis.

1953 • 703 citations

Rectal biopsy as an aid to cancer control in ulcerative colitis.

1967 • 580 citations

GENETICS OF HUMAN CANCER

1986 • 565 citations

HEREDITY WITH REFERENCE TO CARCINOMA

1913 • 501 citations

Retinoblastoma: Clues to Human Oncogenesis

1984 • 495 citations

Malignant tumors of the central nervous system associated with familial polyposis of the colon

1959 • 471 citations

Cancer: Principles and Practice of Oncology

1983 • 456 citations

Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). I. Clinical description of resource

1985 • 402 citations

Malignant Activation of a K- ras Oncogene in Lung Carcinoma But Not in Normal Tissue of the Same Patient

1984 • 395 citations

Cancer family “G” revisited: 1895-1970

1971 • 365 citations

Family studies in cancer of the colon and rectum

1976 • 327 citations

Carcinogenesis—A Comprehensive survey

1982 • 311 citations

Hereditary with reference to carcinoma as shown by the study of the cases examined in a pathological laboratory of the University of Michigan, 1895-1913

1913 • 295 citations

CANCER SURVEILLANCE IN ULCERATIVE COLITIS

1983 • 291 citations

Relationship of Polyps of the Colon to Colonic Cancer

1958 • 283 citations

Report of the committee on human gene mapping by recombinant DNA techniques

1984 • 274 citations

Familial Polyposis Coli

1978 • 273 citations

Monoclonal antibody detection of a circulating tumor-associated antigen. I. Presence of antigen in sera of patients with colorectal, gastric, and pancreatic carcinoma

1982 • 237 citations

Dominant Inheritance of Adenomatous Colonic Polyps and Colorectal Cancer

1985 • 231 citations

The Cancer Family Syndrome Rare Cutaneous Phenotypic Linkage of Torre's Syndrome

1981 • 229 citations

Association of Thyroid Carcinoma with Gardner's Syndrome in Siblings

1968 • 225 citations

Hypertrophy of the Retinal Pigment Epithelium Associated with Gardner's Syndrome

1980 • 202 citations

Pancreatic carcinoma and hereditary nonpolyposis colorectal cancer: A family study

1985 • 198 citations

Elevated expression of the human ras oncogene family in premalignant and malignant tumours of the colorectum

1984 • 195 citations

Tritiated thymidine (phi p, phi h) labeling distribution as a marker for hereditary predisposition to colon cancer.

1983 • 191 citations

Familial Polyposis Coli

1976 • 187 citations

Dietary factors in colon cancer: International relationships

1985 • 187 citations

Fecal Blood Levels in Health and Disease

1985 • 179 citations

The Epidemiology of Large-Bowel Cancer

1978 • 176 citations

Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). II. Biomarker studies

1985 • 165 citations

The occurrence of desmoids in patients with familial polyposis coli

1970 • 164 citations

Family Occurrences of Ulcerative Colitis, Regional Enteritis, and Ileocolitis

1963 • 160 citations

The occult osteomatous changes in the mandible in patients with familial polyposis coli

1975 • 158 citations

Familial juvenile polyposis coli; increased risk of colorectal cancer.

1984 • 156 citations

IMMUNOLOGICAL STUDIES IN ULCERATIVE COLITIS

1968 • 148 citations

Natural history of hereditary cancer of the breast and colon

1982 • 146 citations

Muir-Torre syndrome in several members of a family with a variant of the Cancer Family Syndrome

1985 • 144 citations

Familial Colonic Cancer Without Antecedent Polyposis

1984 • 138 citations

Upper gastrointestinal tract polyps in familial adenomatosis coli.

1983 • 132 citations

Acromegaly and Colon Cancer

1984 • 126 citations

Gastrointestinal Tract Cancer

1978 • 123 citations

Upper gastrointestinal polyps in Gardner's syndrome

1984 • 121 citations

Cancer Statistics, 1984

1984 • 120 citations

The association of familial polyposis of the colon with multiple sebaceous cysts

1954 • 119 citations

Association between hepatoblastoma and polyposis coli.

1983 • 117 citations

Generalized Juvenile Gastrointestinal Polyposis

1970 • 117 citations

Seventh-day Adventist vegetarians have a quiescent proliferative activity in colonic mucosa

1985 • 115 citations

Periampullary Malignancy in Gardnerʼs Syndrome

1977 • 113 citations

Traité des tumeurs

1866 • 111 citations

Multiple primary malignancies arising in the rectum, brain, and thyroid; report of a case.

1949 • 108 citations

Colon cancer genetics

1992 • 107 citations

Classification and risk assessment of individuals with familial polyposis, Gardner's syndrome, and familial non-polyposis colon cancer from [3H]thymidine labeling patterns in colonic epithelial cells.

1984 • 106 citations

Gardner's syndrome and periampullary malignancy

1967 • 106 citations

Progress report. Familial inflammatory bowel disease--heredity or environment?

1976 • 101 citations

Increased Risk of Colorectal Cancer After Cholecystectomy

1981 • 97 citations

Somatic Activation of ras ^K Gene in a Human Ovarian Carcinoma

1984 • 97 citations

Family History in an Oncology Clinic

1979 • 96 citations

The Glioma-Polyposis Syndrome

1969 • 96 citations

Genetics and Breast Cancer

1980 • 96 citations

The Epidemiology of Diet and Cancer

1984 • 95 citations

Familial polyposis coli associated with extracolonic abnormalities

1970 • 89 citations

Lesions associated with familial polyposis coli: Studies of lesions of the stomach, duodenum, bones, and teeth

1976 • 89 citations

Relationship of diet to serum lipids

1984 • 87 citations

Multiple Hamartoma Syndrome (Cowden's Disease)

1978 • 86 citations

Ulcerative Colitis

1950 • 86 citations

Ileal adenomas after colectomy in nine patients with adenomatous polyposis coli/Gardner's syndrome

1979 • 85 citations

The cancer family syndrome: a status report.

1981 • 83 citations

Experimental Intestinal Cancer Research with Special Reference to Human Pathology

1979 • 80 citations

Epidermoid cysts, polyposis coli and Gardner's syndrome

1975 • 78 citations

Oncogenes and proto-oncogenes: How do they differ?

1984 • 78 citations

Defective organization of actin in cultured skin fibroblasts from patients with inherited adenocarcinoma

1977 • 78 citations

Experimental adenomas and carcinomas of the large intestine behave as distinct entities: Most carcinomas arisede novo in flat mucosa

1981 • 76 citations

Gastric and duodenal polyps in familial polyposis coli.

1981 • 75 citations

Gastrointestinal tumors in acromegalic patients.

1985 • 74 citations

Polyposis of the stomach and small intestine in association with familial polyposis coli

1971 • 73 citations

Reduced Capacity for DNA Repair Synthesis in Patients With or Genetically Predisposed to Colorectal Cancer<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 71 citations

Immunological Studies in Ulcerative Colitis

1971 • 70 citations

GARDNER'S SYNDROME WITH ADRENAL CARCINOMA

1967 • 63 citations

Mandibular osteomas in familial polyposis coli

1984 • 63 citations

Gardner's stigmas in patients with familial adenomatosis coli

1982 • 63 citations

Turcot's syndrome evidence for autosomal dominant inheritance

1983 • 63 citations

Adrenal adenomas in a patient with Gardner's syndrome

1981 • 62 citations

Segregation analysis of hereditary nonpolyposis colorectal cancer

1986 • 62 citations

Multiple neoplasms in an adolescent child associated with IgA deficiency

1974 • 62 citations

Adrenal adenomas and adrenal carcinomas in association with hereditary adenomatosis of the colon and rectum

1985 • 62 citations

A Genetic Study of Ulcerative Colitis

1966 • 61 citations

Biliary involvement in familial adenomatosis coli

1983 • 59 citations

Heredity in ankylosing spondylitis; a study of fifty families.

1950 • 56 citations

Small bowel cancers, B-cell lymphatic leukemia, and six primary cancers with metastases and prolonged survival in the cancer family syndrome of lynch

1985 • 53 citations

The Surgeon, Genetics, and Cancer Control

1977 • 52 citations

Gastric Adenocarcinoma Complicating Gardner's Syndrome in a North American Woman

1985 • 51 citations

Increasedin vitro tetraploidy: Tissue specific within the heritable colorectal cancer syndromes with polyposis coli

1978 • 50 citations

Nondegradation of fecal cholesterol in subjects at high risk for cancer of the large intestine.

1981 • 50 citations

Hereditary nonpolyposis colorectal cancer in a Navajo Indian family

1985 • 48 citations

Involvement of the Stomach in Familial Polyposis of the Gastro-Intestinal Tract Report of a Family

1950 • 48 citations

Binding of <italic>Ulex europaeus</italic> Agglutinin-I in Polyposis Coli: Comparative Study With Solitary Adenoma in the Sigmoid Colon and Rectum<xref ref-type="fn" rid="FN2">2</xref>

1983 • 47 citations

Gardner's syndrome

1970 • 47 citations

Incidence of osteosclerotic areas in the mandible and maxilla

1960 • 47 citations

Cancer-associated genodermatoses

2003 • 44 citations

Familial polyposis coli associated with bile duct cancer

1981 • 44 citations

Heredity of Carcinoma in Man

1931 • 41 citations

Hereditary Colon Cancer: Polyposis and Nonpolyposis Variants

1985 • 38 citations

Familial polyposis of the colon and gastric carcinoma. Concurrent conditions in a 16-year-old boy.

1962 • 38 citations

Adenocarcinoma of the rectum arising in a hamartomatous polyp in a patient with Peutz-Jeghers syndrome

1983 • 38 citations

Surveillance/management of an obligate gene carrier: the cancer family syndrome.

1983 • 37 citations

Patterns of mucus secretion in the colonic epithelium in familial polyposis.

1980 • 37 citations

Cancer-Associated Genodermatoses

1983 • 37 citations

The frequent association of other body tumors with familial polyposis.

1959 • 37 citations

Early proliferative defects induced by six weekly injections of 1,2-dimethylhydrazine in epithelial cells of mouse distal colon

1978 • 34 citations

Papillary carcinoma of the thyroid and familial polyposis coli

1983 • 33 citations

Oncogenes: Implications for the Diagnosis and Treatment of Cancer

1984 • 33 citations

Heredity in Ankylosing Spondylitis

1957 • 33 citations

Juvenile polyposis of the colon with atypical adenomatous changes and carcinoma in Situ

1984 • 32 citations

Coexisting primary malignant lymphoma and adenocarcinoma of the large intestine in an IgA-deficient boy

1984 • 31 citations

Familial polyposis associated with a new type of soft-tissue lesion (skin pigmentation)

1967 • 31 citations

Genetic Predisposition to Cancer in Man: In Vitro Studies

1982 • 31 citations

Hl-a in cancer family “n”

1975 • 30 citations

Familial ulcerative colitis

1965 • 30 citations

Colorectal Cancer

1984 • 28 citations

Breast cancer and polyps of the colon: A case–control study

1984 • 28 citations

Familial polyposis coli: heterogeneous polyp expression in 2 kindreds.

1979 • 26 citations

Polyposis and carcinoma of the small bowel and familial colonic polyposis

1981 • 25 citations

Morphologic Transformation and Chromosomal Changes Induced by Chemical Carcinogens in Skin Fibroblasts From Patients With Familial Adenomatosis Coli<xref ref-type="fn" rid="fn2">2</xref>

1982 • 24 citations

Impaired B-cell differentiation and T-cell regulatory function in four patients with Bloom's syndrome

1982 • 23 citations

Early identification of individuals at increased risk for cancer of the large intestine. Part I: definition of high risk populations.

1981 • 23 citations

Hereditary Colorectal Cancer Review: Colonic Polyposis and Nonpolyposis Colonic Cancer (Lynch Syndrome I and II)

1984 • 23 citations

Increased sensitivity of fibroblasts of skin from patients with adenomatosis coli and Peutz-Jegher's syndrome to transformation by murine sarcoma virus.

1980 • 22 citations

Delay: A Deterrent to Cancer Detection

1968 • 21 citations

The Occurrence of Chronic Ulcerative Colitis in Twin Males

1950 • 20 citations

Familial heterogeneity of colon cancer risk

1986 • 20 citations

Hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II): A common genotype linked to oncogenes?

1985 • 19 citations

Heterogeneous Response to X-Ray and Ultraviolet Light Irradiations of Cultured Skin Fibroblasts in Two Families With Gardner's Syndrome<xref ref-type="fn" rid="fn2">2</xref>

1982 • 19 citations

Intestinal polyposis and brain tumor in a family

1979 • 19 citations

Clinical Notes

1962 • 18 citations

Tumor Promoter Induces Loss of Anchorage Dependence in Human Skin Fibroblasts from Individuals Genetically Predisposed to Cancer

1980 • 18 citations

A linkage study of HLA and inherited adenocarcinoma of the colon

1981 • 18 citations

A high incidence of mitotic chiasmata in endoreduplicated Bloom's syndrome cells

1981 • 18 citations

Heredity and Gastrointestinal Tract Cancer

1978 • 18 citations

Hepatocellular carcinoma associated with familial polyposis of the colon

1983 • 18 citations

Role of bile acids and neutral sterols in familial cancer syndromes of the colon

1983 • 17 citations

Mucoid Colonic Carcinoma as an Autosomal-Dominant Inherited Syndrome

1981 • 16 citations

Polyposis coli preceded by hepatocellular carcinoma: report of a case.

1981 • 16 citations

Suppressor cells in healthy relatives of patients with hereditary colon cancer

1980 • 15 citations

CHOLECYSTECTOMY AND COLON CANCER IN THE ELDERLY

1983 • 15 citations

The use of a tumor promoter for the detection of individuals with the gardner syndrome

1983 • 14 citations

Thyroid Carcinoma with Gardner's Syndrome

1968 • 14 citations

Delay factors in detection of cancer of the penis.

1969 • 14 citations

Phenotypic variation in hereditary adenomatosis

1982 • 14 citations

Colorectal cancer in a nuclear family

1985 • 13 citations

Familial Occurrence of Non‐specific Suppurative Coloproctitis

1936 • 13 citations

Carcinoma in situ of the colon

1970 • 13 citations

Immunogenetic studies of familial large bowel cancer.

1980 • 12 citations

New concepts of cancer.

1983 • 12 citations

Genetic implications in ulcerative colitis.

1971 • 12 citations

Colorectal Polyposis Syndromes

1984 • 12 citations

Breast carcinoma and delay in treatment.

1969 • 11 citations

Monozygotic twins with ulcerative colitis

1982 • 11 citations

Genetic and communicable effects on carcinoembryonic antigen expressivity in the cancer family syndrome.

1978 • 11 citations

Clinical Ecogenetics of Human Cancer

2015 • 10 citations

Effect of incubation temperature on the frequency of sister chromatid exchanges in Bloom's syndrome lymphocytes

1981 • 10 citations

The syndrome of congenital telangiectatic erythema and stunted growth

1971 • 8 citations

Differential response of familial polyposis fibroblasts to two bifunctional alkylating agents

1982 • 8 citations

Familial aggregation of neuroectodermal and gastrointestinal tumors

1983 • 8 citations

The effect of aphidicolin on the rate of DNA replication and unscheduled DNA synthesis of Bloom syndrome and normal fibroblasts

1982 • 7 citations

Is cancer of the colon familial in cotton-top tamarins?

1985 • 7 citations

Site-specific, simultaneous presentation of colonic carcinoma in identical twins

1983 • 6 citations

Adenomas and carcinomas of the large bowel. Distinct diseases possibly sharing common etiologic factors?

1982 • 6 citations

Attitudes and Delay in Cancer Detection

1968 • 5 citations

T Cells, Precocious Aging, and Familial Neoplasia

1978 • 5 citations

Familial multiple polyposis coli with multiple associated tumors

1983 • 5 citations

Aldred Scott Warthin 1866–1931

1931 • 5 citations

Preventive oncology

1975 • 4 citations

IBD in families, pregnancy, and childhood.

1983 • 4 citations

Familial colorectal cancer and hereditary brachydactyly.

1981 • 4 citations

The delay problem in cancer.

1972 • 3 citations

Embryonal carcinoma of the testis associated with familial adenomatosis coli

1985 • 2 citations

MEETINGS 1983

1983 • 2 citations

Delay: a problem in cancer control.

1970 • 1 citations

Intestinal cancer in Crohn's disease.

1984 • 1 citations