Hormonal control of pyruvate dehydrogenase activity in rat liver

Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase

1972 • 519 citations

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide

1976 • 399 citations

Regulation of adipose tissue pyruvate dehydrogenase by insulin and other hormones

1971 • 388 citations

α-KETO ACID DEHYDROGENASE COMPLEXES, XI. COMPARATIVE STUDIES OF REGULATORY PROPERTIES OF THE PYRUVATE DEHYDROGENASE COMPLEXES FROM KIDNEY, HEART, AND LIVER MITOCHONDRIA

1969 • 355 citations

On the role of calcium as second messenger in liver for the hormonally induced activation of glycogen phosphorylase

1977 • 309 citations

Role of calcium ions in the regulation of intramitochondrial metabolism. Effects of Na+, Mg2+ and ruthenium red on the Ca2+-stimulated oxidation of oxoglutarate and on pyruvate dehydrogenase activity in intact rat heart mitochondria

1980 • 292 citations

Studies on alpha-adrenergic activation of hepatic glucose output. Studies on role of calcium in alpha-adrenergic activation of phosphorylase.

1977 • 289 citations

Control of hepatic glycogenolysis.

1980 • 288 citations

Active and inactive forms of pyruvate dehydrogenase in rat heart and kidney: Effect of diabetes, fasting, and refeeding on pyruvate dehydrogenase interconversion

1971 • 231 citations

THE ENZYMATIC ACETYLATION OF AMINES

1953 • 209 citations

Hormonal and ionic control of the glycogenolytic cascade in rat liver

1977 • 198 citations

Role of calcium ions in the regulation of intramitochondrial metabolism. Properties of the Ca2+-sensitive dehydrogenases within intact uncoupled mitochondria from the white and brown adipose tissue of the rat

1980 • 157 citations

Stimulation by vasopressin of glycogen breakdown and gluconeogenesis in the perfused rat liver

1973 • 147 citations

Short-term regulation of liver metabolism

1982 • 142 citations

Phosphorylation state of cytosolic and mitochondrial adenine nucleotides and of pyruvate dehydrogenase in isolated rat liver cells

1976 • 133 citations

Evidence for mitochondrial localization of the hormone-responsive pool of Ca2+ in isolated hepatocytes.

1979 • 128 citations

The Interaction of Liver Phosphorylase a with Glucose and AMP

1974 • 114 citations

Purification of porcine liver pyruvate dehydrogenase complex and characterization of its catalytic and regulatory properties

1977 • 113 citations

Rapid stimulation by vasopressin, oxytocin and angiotensin II of glycogen degradation in hepatocyte suspensions

1978 • 111 citations

The mode of regulation of pyruvate dehydrogenase of lactating rat mammary gland. Effects of starvation and insulin

1978 • 77 citations

Glycogen phosphorylase, glucose output and vasoconstriction in the perfused rat liver. Concentration-dependence of actions of adrenaline, vasopressin and angiotensin II

1976 • 67 citations

Role of extracellular calcium in the action of vasopressin on hepatic glycogenolysis

1976 • 64 citations

Activation of pyruvate dehydrogenase in adipose tissue by insulin. Evidence for an effect of insulin on pyruvate dehydrogenase phosphate phosphatase

1975 • 62 citations

Metabolic actions of vasopressin, glucagon and adrenalin in the intact rat

1975 • 59 citations

Activation of pyruvate dehydrogenase in the perfused rat liver by vasopressin

1978 • 54 citations

Effect of dichloroacetate and glucagon on the incorporation of labeled substrates into glucose and on pyruvate dehydrogenase in hepatocytes from fed and starved rats

1977 • 44 citations

Mechanisms involved in alpha-adrenergic effects of catecholamines on liver metabolism.

1979 • 41 citations

The activation of Na+-dependent efflux of Ca2+ from liver mitochondria by glucagon and β-adrenergic agonists

1983 • 38 citations

Inhibition of fatty acid synthesis and stimulation of glycogen breakdown by vasopressin in the perfused mouse liver

1975 • 37 citations

Decreased flux through pyruvate dehydrogenase during calcium ion movements induced by vasopressin, α-adrenergic agonists and the ionophore A23187 in perfused rat liver

1983 • 37 citations

Influence of Extracellular Calcium Ions on Hormonal Stimulation of Glycogen Breakdown in Hepatocyte Suspensions

1977 • 13 citations