Purification of porcine liver pyruvate dehydrogenase complex and characterization of its catalytic and regulatory properties

Methods in Enzymology , Vol

1966 • 26,261 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Equilibrium Ultracentrifugation of Dilute Solutions^*

1964 • 3,399 citations

Hydrogen Ion Buffers for Biological Research^*

1966 • 2,690 citations

The dependence of contraction and relaxation of muscle fibres from the crab Maia squinado on the internal concentration of free calcium ions

1964 • 1,034 citations

Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase

1972 • 519 citations

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide

1976 • 399 citations

Regulation of adipose tissue pyruvate dehydrogenase by insulin and other hormones

1971 • 388 citations

Proteinase Inhibitors

1974 • 327 citations

Regulation of pyruvate dehydrogenase kinase and phosphatase by acetyl-CoA/CoA and NADH/NAD ratios

1975 • 303 citations

Regulation of mammalian pyruvate dehydrogenase

1975 • 299 citations

α-Keto acid dehydrogenase complexes

1972 • 282 citations

α-Keto acid dehydrogenase complexes

1972 • 278 citations

α-Keto acid dehydrogenase complexes

1972 • 244 citations

Regulation of heart muscle pyruvate dehydrogenase kinase

1974 • 227 citations

Active and Inactive Forms of Pyruvate Dehydrogenase in Rat Liver

1972 • 199 citations

Function of calcium ions in pyruvate dehydrogenase phosphatase activity

1972 • 157 citations

α-Keto Acid Dehydrogenase Complexes

1973 • 149 citations

Microsomal Oxidases. I. The Isolation and Dialkylarylamine Oxygenase Activity of Pork Liver Microsomes^*

1966 • 127 citations

Hormonal regulation of pyruvate dehydrogenase

1971 • 127 citations

Interconversion and Kinetic Properties of Pyruvate Dehydrogenase from Brain

1971 • 127 citations

Regulation of pyruvate dehydrogenase by fatty acid in isolated rat liver mitochondria.

1976 • 120 citations

Studies on the effects of coenzyme A-SH: acetyl coenzyme A, nicotinamide adenine dinucleotide: reduced nicotinamide adenine dinucleotide, and adenosine diphosphate: adenosine triphosphate ratios on the interconversion of active and inactive pyruvate dehydrogenase in isolated rat heart mitochondria.

1976 • 117 citations

Purification and Characterization of Pyruvate‐Dehydrogenase Phosphatase from Pig‐Heart Muscle

1972 • 110 citations

Kinetic and Regulatory Properties of Heart Muscle Pyruvate Dehydrogenase

1969 • 107 citations

Isoelectric fractionation of proteins on a microscale in polyacrylamide and agarose matrices.

1968 • 99 citations

Interconversion of Pyruvate Dehydrogenase in the Isolated Perfused Rat Liver

1973 • 94 citations

Function of the nonidentical subunits of mammalian pyruvate dehydrogenase

1972 • 93 citations

Protein Phosphorylation in Control Mechanisms

1973 • 87 citations

Activation of Pyruvate Dehydrogenase during Metabolism of Ammonium Ions in Hemoglobin‐Free Perfused Rat Liver

1975 • 85 citations

Regulation of pyruvate dehydrogenase in isolated rat liver mitochondria. Effects of octanoate, oxidation-reduction state, and adenosine triphosphate to adenosine diphosphate ratio.

1975 • 80 citations

Regulation of pyruvate dehydrogenase in isolated rat liver mitochondria. Effects of octanoate, oxidation-reduction state, and adenosine triphosphate to adenosine diphosphate ratio.

1975 • 75 citations

Monovalent cation requirement for ADP inhibition of pyruvate dehydrogenase kinase

1974 • 75 citations

Derivation of Rate Equations for Multisite Ping-Pong Mechanisms with Ping-Pong Reactions at One or More Sites

1973 • 69 citations

Relation of mitochondrial phospholipase A activity to mitochondrial swelling

1969 • 62 citations

Evidence for lipoic acid mediated NADH and acetyl-CoA stimulation of liver and kidney pyruvate dehydrogenase kinase

1976 • 46 citations

On the mechanism of irreversible pyruvate dehydrogenase inactivation in liver mitochondrial extracts

1975 • 37 citations

Studies on the apparent instability of bovine kidney α-ketoglutarate dehydrogenase complex

1974 • 33 citations