Towards an understanding of the biological function of histone acetylation

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

1964 • 2,410 citations

Effects of sodium butyrate, a new pharmacological agent, on cells in culture

1981 • 808 citations

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

1987 • 609 citations

Transcriptionally active chromatin

1984 • 361 citations

Eukaryotic RNA polymerase II binds to nucleosome cores from transcribed genes

1983 • 224 citations

Histone hyperacetylation: its effects on nucleosome conformation and stability

1986 • 211 citations

Nonrandom utilization of acetylation sites in histones isolated from Tetrahymena. Evidence for functionally distinct H4 acetylation sites.

1986 • 142 citations

Deposition-related histone acetylation in micronuclei of conjugating Tetrahymena.

1985 • 137 citations

Acetylation of histones in nucleosomes

1982 • 108 citations

Hyperacetylation of histone H4 promotes chromatin decondensation prior to histone replacement by protamines during spermatogenesis in rainbow trout

1984 • 103 citations

Hyperacetylation of histone H4 correlates with the terminal, transcriptionally inactive stages of spermatogenesis in rainbow trout

1982 • 98 citations

Hyperacetylation of histone H4 in rat testis spermatids

1984 • 91 citations

Histone hyperacetylation has little effect on the higher order folding of chromatin

1983 • 83 citations

Hyperacetylation of core histones does not cause unfolding of nucleosomes. Neutron scatter data accords with disc shape of the nucleosome.

1986 • 75 citations

Histone H4 from cuttlefish testis is sequentially acetylated. Comparison with acetylation of calf thymus histone H4.

1987 • 70 citations

From macromolecules to biological assemblies

1983 • 63 citations

Altered nucleosomes of active nucleolar chromatin contain accessible histone H3 in its hyperacetylated forms.

1987 • 60 citations

Immunochemical detection of changes in chromatin subunits induced by histone H4 acetylation.

1982 • 49 citations

Postsynthetic acetylation of histones during the cell cycle: a general function for the displacement of histones during chromatin rearrangements

1987 • 48 citations

Histone synthesis during the cell cycle of Physarum polycephalum. Synthesis of different histone species is not under a common regulatory control.

1987 • 40 citations

Lack of correlation between histone H4 acetylation and transcription during the Physarum cell cycle

1983 • 37 citations

Interaction of tubulin with chromatin proteins. H1 and core histones.

1984 • 28 citations

Interaction with RNA polymerase of nucleosomal cores lacking one H2A.H2B dimer.

1987 • 27 citations

Biosynthesis and posttranslational acetylation of histones during spherulation ofPhysarum polycephalum

1986 • 23 citations

RNA polymerase activity and template activity of chromatin after butyrate induced hyperacetylation of histones inPhysarum

1984 • 19 citations

Interactions of the nuclear thyroid hormone receptor with core histones.

1984 • 18 citations

Depression of histone acetylation by alkylating antitumor agents in murine cells.

1984 • 9 citations

Evidence for attachment of interphase chromatin to the nuclear matrix via matrix-bound nucleosomes

1984 • 4 citations