Deficiency of plasma plasminogen activator inhibitor 1 results in hyperfibrinolytic bleeding

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Increased Plasma Levels of a Rapid Inhibitor of Tissue Plasminogen Activator in Young Survivors of Myocardial Infarction

1985 • 1,364 citations

Platelets and Thrombolytic Therapy

1990 • 485 citations

Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin).

1988 • 484 citations

Differential sensitivity of erythrocyte-rich and platelet-rich arterial thrombi to lysis with recombinant tissue-type plasminogen activator. A possible explanation for resistance to coronary thrombolysis.

1989 • 473 citations

Two different mechanisms in patients with venous thrombosis and defective fibrinolysis: low concentration of plasminogen activator or increased concentration of plasminogen activator inhibitor.

1985 • 341 citations

Fibrinolysis in pregnancy: a study of plasminogen activator inhibitors

1987 • 327 citations

Plasminogen activator inhibitor in the blood of patients with coronary artery disease.

1985 • 311 citations

Plasminogen activator inhibitor (PAI‐1) in plasma and platelets

1988 • 299 citations

Significance of Cross-Linking of α2-Plasmin Inhibitor to Fibrin in Inhibition of Fibrinolysis and in Hemostasis

1982 • 287 citations

Type 1 plasminogen activator inhibitor

1990 • 244 citations

Bleeding diathesis due to decreased functional activity of type 1 plasminogen activator inhibitor.

1989 • 208 citations

The role of the fibrinolytic system in deep vein thrombosis.

1985 • 201 citations

Congenital Deficiency of α2-Plasmin Inhibitor Associated with Severe Hemorrhagic Tendency *

1979 • 201 citations

Plasminogen activator inhibitor 1: development of a radioimmunoassay and observations on its plasma concentration during venous occlusion and after platelet aggregation

1987 • 195 citations

Regulation of PAI-1 gene expression

1991 • 184 citations

Daytime Fluctuations in Blood of Tissue-Type Plasminogen Activator (t-PA) and Its Fast-Acting Inhibitor (PAI-1)

1988 • 183 citations

Plasminogen activator inhibitor 1 (PAI) is bound to vitronectin in plasma

1988 • 178 citations

A lifelong bleeding disorder associated with a deficiency of plasminogen activator inhibitor type 1

1991 • 153 citations

Measurement of human tissue-type plasminogen activator by a two-site immunoradiometric assay.

1983 • 142 citations

Identification of and partial characterization of platelet vitronectin: evidence for complex formation with platelet-derived plasminogen activator inhibitor-1

1989 • 114 citations

Inhibition of clot lysis and decreased binding of tissue-type plasminogen activator as a consequence of clot retraction

1992 • 108 citations

Blood Platelet Plasminogen Activator Inhibitor: Two Different Pools of Endothelial Cell Type Plasminogen Activator Inhibitor in Human Blood

1986 • 103 citations

The interaction of plasminogen activator inhibitor 1 with plasminogen activators (tissue-type and urokinase-type) and fibrin: localization of interaction sites and physiologic relevance

1991 • 99 citations

A familial factor XIII subunit B deficiency

1990 • 75 citations

A new life-long hemorrhagic disorder due to excess plasminogen activator

1983 • 62 citations

Release of vascular plasminogen activator (v‐PA) after venous stasis: electrophoretic—zymographic analysis of free and complexed v‐PA

1985 • 56 citations

A Kinetic Model of the Circulatory Regulation of Tissue Plasminogen Activator

1991 • 47 citations

Preoperative Identification of Patients at High Risk of Deep Venous Thrombosis Despite Prophylaxis in Total Hip Replacement

1988 • 45 citations

The platelet and plasma pools of plasminogen activator inhibitor (PAI‐1) vary independently in disease

1990 • 44 citations

Fibrinogen Ledyard (A alpha Arg16----Cys): biochemical and physiologic characterization

1991 • 20 citations

Increased levels of tissue plasminogen activator with a low plasminogen activator inhibitor‐1 in a patient with postoperative bleeding

1991 • 14 citations

Open-Heart Surgery in a Patient with Heterozygous α2-Antiplasmin Deficiency

1990 • 9 citations